STRINGSTRING
FGF16 FGF16 GPC1 GPC1 MET MET BTC BTC FGFRL1 FGFRL1 VEGFC VEGFC IGF1R IGF1R PIR PIR KDR KDR KIT KIT ANOS1 ANOS1 PDGFRA PDGFRA NRG4 NRG4 EREG EREG KLB KLB ANGPTL2 ANGPTL2 LOC103271953 LOC103271953 LOC103271002 LOC103271002 NRG3 NRG3 ERBB4 ERBB4 VEGFD VEGFD EGF EGF LCTL LCTL AREG AREG FGFR2 FGFR2 ANGPT1 ANGPT1 PDGFRL PDGFRL PDGFC PDGFC FLT3 FLT3 HBEGF HBEGF ANGPT2 ANGPT2 PDGFD PDGFD ANGPTL7 ANGPTL7 HGF HGF TIE1 TIE1 FGF5 FGF5 ERBB2 ERBB2 FGF6 FGF6 LOC103264991 LOC103264991 FGF11 FGF11 FGF3 FGF3 NTRK2 NTRK2 FGF7 FGF7 FRS2 FRS2 LOC103276437 LOC103276437 FGF1 FGF1 VEGFA VEGFA LOC103267910 LOC103267910 DOK2 DOK2 TEK TEK FGF20 FGF20 FGF20-2 FGF20-2 FGF17 FGF17 FGF10 FGF10 TGFA TGFA FGF9 FGF9 FGFR1 FGFR1 KITLG KITLG FGF21 FGF21 NRP2 NRP2 LOC103275563 LOC103275563 FGFR3 FGFR3 IL34 IL34 KL KL FGF18 FGF18 CSF1 CSF1 VEGFB VEGFB NRG1 NRG1 ANGPT4 ANGPT4 S100A13 S100A13 IGF1 IGF1 PDGFB PDGFB EPGN EPGN PGF PGF ENSTSYP00000033115 ENSTSYP00000033115 PDGFA PDGFA NRG2 NRG2 FLT3LG FLT3LG CSF1R CSF1R
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
GPC1Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
METHepatocyte growth factor receptor isoform X1. (1415 aa)
BTCProbetacellulin. (178 aa)
FGFRL1Fibroblast growth factor receptor-like 1. (506 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (407 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
PIRPirin; Belongs to the pirin family. (291 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
KITMast/stem cell growth factor receptor Kit; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (953 aa)
ANOS1Anosmin-1. (595 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
EREGProepiregulin. (167 aa)
KLBBeta-klotho. (835 aa)
ANGPTL2Angiopoietin-related protein 2. (493 aa)
LOC103271953Vascular endothelial growth factor receptor 1-like. (713 aa)
LOC103271002Receptor tyrosine-protein kinase erbB-3. (580 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X2. (344 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (351 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
LCTLLactase-like protein; Belongs to the glycosyl hydrolase 1 family. (566 aa)
AREGAmphiregulin isoform X1. (270 aa)
FGFR2Fibroblast growth factor receptor 2 isoform X1. (615 aa)
ANGPT1Angiopoietin-1 isoform X1. (498 aa)
PDGFRLPlatelet-derived growth factor receptor-like protein. (375 aa)
PDGFCPlatelet-derived growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (345 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (980 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
ANGPT2Angiopoietin-2 isoform X1. (495 aa)
PDGFDPlatelet-derived growth factor D. (370 aa)
ANGPTL7Angiopoietin-related protein 7. (344 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC103264991Vascular endothelial growth factor receptor 1 isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (431 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
NTRK2BDNF/NT-3 growth factors receptor isoform X1. (553 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
LOC103276437Vascular endothelial growth factor receptor 3-like. (295 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
VEGFAVascular endothelial growth factor A isoform X2; Belongs to the PDGF/VEGF growth factor family. (186 aa)
LOC103267910Fibroblast growth factor receptor 2-like. (208 aa)
DOK2Docking protein 2 isoform X1. (410 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
FGF20-2Fibroblast growth factor 20. (75 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TGFATransforming growth factor alpha. (164 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (146 aa)
FGFR1Fibroblast growth factor receptor. (832 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (928 aa)
LOC103275563Receptor tyrosine-protein kinase erbB-3. (169 aa)
FGFR3Fibroblast growth factor receptor. (745 aa)
IL34Interleukin-34 isoform X1. (240 aa)
KLKlotho; Belongs to the glycosyl hydrolase 1 family. (972 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (184 aa)
CSF1Macrophage colony-stimulating factor 1. (244 aa)
VEGFBVascular endothelial growth factor B. (181 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
ANGPT4Angiopoietin-4. (488 aa)
S100A13Protein S100-A13; Belongs to the S-100 family. (98 aa)
IGF1Insulin-like growth factor I isoform X1. (209 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (229 aa)
EPGNEpigen isoform X1. (153 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
ENSTSYP00000033115annotation not available (96 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (202 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform. (243 aa)
FLT3LGFms-related tyrosine kinase 3 ligand. (237 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (965 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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