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| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (404 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase B isoform X1. (677 aa) |
| | PNPLA8 | Calcium-independent phospholipase A2-gamma isoform X2. (781 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase isoform X1. (303 aa) |
| | ACSM6 | Acyl-coenzyme A synthetase ACSM6, mitochondrial. (309 aa) |
| | DAGLB | Sn1-specific diacylglycerol lipase beta. (672 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase. (199 aa) |
| | ACSM2B | Acyl-coenzyme A synthetase ACSM2B, mitochondrial. (577 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase isoform X1. (665 aa) |
| | ABHD3 | Phospholipase ABHD3. (409 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X1. (343 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S-type. (663 aa) |
| | LIPC | Hepatic triacylglycerol lipase. (499 aa) |
| | ENSTSYP00000033658 | annotation not available (79 aa) |
| | LOC103255277 | thromboxane-A synthase-like. (114 aa) |
| | LOC103252213 | Breast cancer type 1 susceptibility protein-like. (97 aa) |
| | ASAH2 | Neutral ceramidase. (768 aa) |
| | LOC103269085 | Glutathione S-transferase. (218 aa) |
| | OLAH | S-acyl fatty acid synthase thioesterase, medium chain. (312 aa) |
| | ACACA | acetyl-CoA carboxylase 1. (2383 aa) |
| | LIPG | Endothelial lipase-like. (347 aa) |
| | LOC103269084 | Glutathione S-transferase. (203 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (180 aa) |
| | LOC103256667 | Hepatocyte nuclear factor 1-alpha isoform X2. (227 aa) |
| | CBR4 | Carbonyl reductase family member 4. (214 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R-type. (700 aa) |
| | ENSTSYP00000028789 | annotation not available (176 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | TMEM196 | Transmembrane protein 196. (182 aa) |
| | PCCB | propionyl-CoA carboxylase subunit beta. (477 aa) |
| | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2 isoform X1. (272 aa) |
| | SCD | acyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (352 aa) |
| | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform X3. (510 aa) |
| | LOC103255116 | Arachidonate 12-lipoxygenase, epidermal-type-like. (629 aa) |
| | LOC103253950-2 | Fatty acid desaturase 1 isoform X1. (360 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase 2-like, mitochondrial. (605 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) |
| | THNSL2 | Threonine synthase-like 2. (484 aa) |
| | PTGES2 | Prostaglandin E synthase 2. (187 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (663 aa) |
| | FADS3 | Fatty acid desaturase 3 isoform X1. (401 aa) |
| | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1 isoform X1. (270 aa) |
| | GSTP1 | LOW QUALITY PROTEIN: glutathione S-transferase P; Belongs to the GST superfamily. (184 aa) |
| | QKI | Protein quaking isoform X2. (277 aa) |
| | ENSTSYP00000024721 | annotation not available (128 aa) |
| | RPP14-2 | Ribonuclease P protein subunit p14 isoform X1. (152 aa) |
| | LOC103269077 | Glutathione S-transferase Mu 2 isoform X1. (238 aa) |
| | ABCD1 | ATP-binding cassette sub-family D member 1. (745 aa) |
| | PLA2G1B | Phospholipase A(2). (147 aa) |
| | LOC103258048 | Fatty acid desaturase 2-like protein FADS2P1. (482 aa) |
| | PTGIS | Prostacyclin synthase. (496 aa) |
| | PTGS1 | Prostaglandin G/H synthase 1 isoform X1. (629 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (279 aa) |
| | TECR | Very-long-chain enoyl-CoA reductase isoform X2. (308 aa) |
| | ENSTSYP00000019705 | annotation not available (218 aa) |
| | MGLL | Monoglyceride lipase isoform X1. (313 aa) |
| | ENSTSYP00000018856 | annotation not available (161 aa) |
| | HSD17B8 | Estradiol 17-beta-dehydrogenase 8. (259 aa) |
| | ACOT7 | Cytosolic acyl coenzyme A thioester hydrolase. (348 aa) |
| | PLP1 | Myelin proteolipid protein isoform X1. (277 aa) |
| | LIPH | Lipase member H isoform X1. (441 aa) |
| | MIF | Macrophage migration inhibitory factor. (115 aa) |
| | DECR2 | Peroxisomal 2,4-dienoyl-CoA reductase. (294 aa) |
| | DEGS1 | Sphingolipid delta(4)-desaturase DES1. (323 aa) |
| | FASN | Fatty acid synthase isoform X1. (2508 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain. (166 aa) |
| | PTGES | Prostaglandin E synthase. (156 aa) |
| | ABCD3 | ATP-binding cassette sub-family D member 3. (640 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | ACACB | LOW QUALITY PROTEIN: acetyl-CoA carboxylase 2. (2433 aa) |
| | TBXAS1 | thromboxane-A synthase; Belongs to the cytochrome P450 family. (383 aa) |
| | ACSM4 | Acyl-coenzyme A synthetase ACSM4, mitochondrial. (579 aa) |
| | MECR | Enoyl-[acyl-carrier-protein] reductase, mitochondrial. (373 aa) |
| | EDN2 | Endothelin-2. (178 aa) |
| | ARMC7 | Armadillo repeat-containing protein 7 isoform X1. (198 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (604 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein. (260 aa) |
| | ACSM3 | Acyl-coenzyme A synthetase ACSM3, mitochondrial. (586 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (529 aa) |
| | EDN1 | Endothelin-1. (202 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3. (489 aa) |
| | HSDL1 | Inactive hydroxysteroid dehydrogenase-like protein 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | ENSTSYP00000010229 | annotation not available (257 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1150 aa) |
| | CYP2C8 | Cytochrome P450 family 2 subfamily C member 8. (463 aa) |
| | ACSF3 | acyl-CoA synthetase family member 3, mitochondrial. (569 aa) |
| | PTGES3 | Prostaglandin E synthase 3 isoform X3. (160 aa) |
| | TECRL | trans-2,3-enoyl-CoA reductase-like. (363 aa) |
| | ALOXE3 | Hydroperoxide isomerase ALOXE3. (820 aa) |
| | ENSTSYP00000007785 | annotation not available (217 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | LOC103272478 | LOW QUALITY PROTEIN: acyl-coenzyme A synthetase ACSM1, mitochondrial-like. (567 aa) |
| | ACSBG2 | long-chain-fatty-acid--CoA ligase ACSBG2 isoform X1. (667 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | LOC103263427 | Glutathione S-transferase. (189 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein. (314 aa) |
| | LOC103263247 | Arachidonate 12-lipoxygenase, 12S-type-like. (669 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (296 aa) |
| | FADS6 | Fatty acid desaturase 6. (330 aa) |
| | MCAT | malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X1. (386 aa) |
| | XBP1 | LOW QUALITY PROTEIN: X-box-binding protein 1. (376 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Belongs to the sterol desaturase family. (318 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (313 aa) |
| | HSD17B12 | Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (273 aa) |
| | HACD2 | 3-hydroxyacyl-CoA dehydratase 2. (160 aa) |
| | ACSM5 | Acyl-coenzyme A synthetase ACSM5, mitochondrial. (579 aa) |
