(22 nodes) Positive regulation of cardiac muscle hypertrophy network (Carlito syrichta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	PARP1	Poly [ADP-ribose] polymerase. (919 aa)
	ROCK1	Rho-associated protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1367 aa)
	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (533 aa)
	ENSTSYP00000014736	annotation not available (112 aa)
	TRPC3	LOW QUALITY PROTEIN: short transient receptor potential channel 3; Belongs to the transient receptor (TC 1.A.4) family. (903 aa)
	ADRA1A	alpha-1A adrenergic receptor isoform X1. (466 aa)
	PDE9A	Phosphodiesterase. (533 aa)
	EDN1	Endothelin-1. (202 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (642 aa)
	AKAP6	A-kinase anchor protein 6. (2242 aa)
	PRKCA	Protein kinase C. (614 aa)
	PARP2	Poly [ADP-ribose] polymerase. (568 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	CDK9	Cyclin-dependent kinase 9. (341 aa)
	MTPN	Myotrophin. (118 aa)
	IGF1	Insulin-like growth factor I isoform X1. (209 aa)
	PDE5A	Phosphodiesterase. (866 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (811 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	ENSTSYP00000021494	annotation not available (522 aa)
	MEF2A	Myocyte-specific enhancer factor 2A isoform X1. (498 aa)
	ROCK2	Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1376 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA1A	EDN1	ENSTSYP00000011047	ENSTSYP00000010445	alpha-1A adrenergic receptor isoform X1.	Endothelin-1.	0.841
CAMK2D	PDE5A	ENSTSYP00000015609	ENSTSYP00000027723	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4.	Phosphodiesterase.	0.601
CAMK2D	PDE9A	ENSTSYP00000015609	ENSTSYP00000010615	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4.	Phosphodiesterase.	0.616
CAMK2D	PPP3CA	ENSTSYP00000015609	ENSTSYP00000023821	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4.	Serine/threonine-protein phosphatase.	0.591
EDN1	ADRA1A	ENSTSYP00000010445	ENSTSYP00000011047	Endothelin-1.	alpha-1A adrenergic receptor isoform X1.	0.841
ENSTSYP00000014736	ENSTSYP00000021494	ENSTSYP00000014736	ENSTSYP00000021494	annotation not available	annotation not available	0.812
ENSTSYP00000014736	PARP2	ENSTSYP00000014736	ENSTSYP00000003629	annotation not available	Poly [ADP-ribose] polymerase.	0.812
ENSTSYP00000021494	ENSTSYP00000014736	ENSTSYP00000021494	ENSTSYP00000014736	annotation not available	annotation not available	0.812
ENSTSYP00000021494	PARP1	ENSTSYP00000021494	ENSTSYP00000003407	annotation not available	Poly [ADP-ribose] polymerase.	0.824
IGF1	ROCK1	ENSTSYP00000029486	ENSTSYP00000016368	Insulin-like growth factor I isoform X1.	Rho-associated protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.467
IGF1	ROCK2	ENSTSYP00000029486	ENSTSYP00000019013	Insulin-like growth factor I isoform X1.	Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.488
MTPN	PPP3CA	ENSTSYP00000032374	ENSTSYP00000023821	Myotrophin.	Serine/threonine-protein phosphatase.	0.434
PARP1	ENSTSYP00000021494	ENSTSYP00000003407	ENSTSYP00000021494	Poly [ADP-ribose] polymerase.	annotation not available	0.824
PARP1	PARP2	ENSTSYP00000003407	ENSTSYP00000003629	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.822
PARP2	ENSTSYP00000014736	ENSTSYP00000003629	ENSTSYP00000014736	Poly [ADP-ribose] polymerase.	annotation not available	0.812
PARP2	PARP1	ENSTSYP00000003629	ENSTSYP00000003407	Poly [ADP-ribose] polymerase.	Poly [ADP-ribose] polymerase.	0.822
PDE5A	CAMK2D	ENSTSYP00000027723	ENSTSYP00000015609	Phosphodiesterase.	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4.	0.601
PDE5A	PDE9A	ENSTSYP00000027723	ENSTSYP00000010615	Phosphodiesterase.	Phosphodiesterase.	0.734
PDE5A	ROCK2	ENSTSYP00000027723	ENSTSYP00000019013	Phosphodiesterase.	Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.406
PDE9A	CAMK2D	ENSTSYP00000010615	ENSTSYP00000015609	Phosphodiesterase.	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4.	0.616