14 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL18	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	CSF1	Macrophage colony-stimulating factor 1. (244 aa)
	MSR1	Macrophage scavenger receptor types I and II isoform X1. (451 aa)
	CD36	Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
	AGTR1	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (387 aa)
	CSF2	Granulocyte-macrophage colony-stimulating factor. (144 aa)
	APOB	Apolipoprotein B-100. (4537 aa)
	AGT	Angiotensinogen; Belongs to the serpin family. (487 aa)
	ALOX15B	Arachidonate 15-lipoxygenase B isoform X1. (677 aa)
	NFKB1	Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	PLA2G2A	Phospholipase A(2). (144 aa)
	PLA2G3	Group 3 secretory phospholipase A2. (506 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	AGTR1	ENSTSYP00000004691	ENSTSYP00000012592	Angiotensinogen; Belongs to the serpin family.	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.	0.998
AGTR1	AGT	ENSTSYP00000012592	ENSTSYP00000004691	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.	Angiotensinogen; Belongs to the serpin family.	0.998
AGTR1	APOB	ENSTSYP00000012592	ENSTSYP00000007628	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.	Apolipoprotein B-100.	0.662
ALOX15B	PLA2G2A	ENSTSYP00000004545	ENSTSYP00000001396	Arachidonate 15-lipoxygenase B isoform X1.	Phospholipase A(2).	0.867
ALOX15B	PLA2G3	ENSTSYP00000004545	ENSTSYP00000001274	Arachidonate 15-lipoxygenase B isoform X1.	Group 3 secretory phospholipase A2.	0.866
APOB	AGTR1	ENSTSYP00000007628	ENSTSYP00000012592	Apolipoprotein B-100.	Type-1 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.	0.662
APOB	CD36	ENSTSYP00000007628	ENSTSYP00000016880	Apolipoprotein B-100.	Platelet glycoprotein 4; Belongs to the CD36 family.	0.897
APOB	MSR1	ENSTSYP00000007628	ENSTSYP00000024409	Apolipoprotein B-100.	Macrophage scavenger receptor types I and II isoform X1.	0.522
APOB	PLA2G5	ENSTSYP00000007628	ENSTSYP00000002864	Apolipoprotein B-100.	Phospholipase A(2).	0.572
CD36	APOB	ENSTSYP00000016880	ENSTSYP00000007628	Platelet glycoprotein 4; Belongs to the CD36 family.	Apolipoprotein B-100.	0.897
CD36	MSR1	ENSTSYP00000016880	ENSTSYP00000024409	Platelet glycoprotein 4; Belongs to the CD36 family.	Macrophage scavenger receptor types I and II isoform X1.	0.519
CD36	NFKB1	ENSTSYP00000016880	ENSTSYP00000004442	Platelet glycoprotein 4; Belongs to the CD36 family.	Nuclear factor NF-kappa-B p105 subunit isoform X1.	0.471
CSF1	CSF2	ENSTSYP00000027365	ENSTSYP00000007992	Macrophage colony-stimulating factor 1.	Granulocyte-macrophage colony-stimulating factor.	0.578
CSF2	CSF1	ENSTSYP00000007992	ENSTSYP00000027365	Granulocyte-macrophage colony-stimulating factor.	Macrophage colony-stimulating factor 1.	0.578
CSF2	IL18	ENSTSYP00000007992	ENSTSYP00000034922	Granulocyte-macrophage colony-stimulating factor.	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	0.525
CSF2	MSR1	ENSTSYP00000007992	ENSTSYP00000024409	Granulocyte-macrophage colony-stimulating factor.	Macrophage scavenger receptor types I and II isoform X1.	0.615
IL18	CSF2	ENSTSYP00000034922	ENSTSYP00000007992	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Granulocyte-macrophage colony-stimulating factor.	0.525
IL18	NFKB1	ENSTSYP00000034922	ENSTSYP00000004442	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.	Nuclear factor NF-kappa-B p105 subunit isoform X1.	0.853
MAPK9	NFKB1	ENSTSYP00000031000	ENSTSYP00000004442	Mitogen-activated protein kinase.	Nuclear factor NF-kappa-B p105 subunit isoform X1.	0.861
MSR1	APOB	ENSTSYP00000024409	ENSTSYP00000007628	Macrophage scavenger receptor types I and II isoform X1.	Apolipoprotein B-100.	0.522