28 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STAP1	Signal-transducing adaptor protein 1. (292 aa)
	EFNA5	ephrin-A5; Belongs to the ephrin family. (228 aa)
	BTC	Probetacellulin. (178 aa)
	ERCC6	DNA excision repair protein ERCC-6. (1481 aa)
	DGKQ	Diacylglycerol kinase. (941 aa)
	AFAP1L2	Actin filament-associated protein 1-like 2. (820 aa)
	EREG	Proepiregulin. (167 aa)
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	ABI1	Abl interactor 1 isoform X1. (498 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1280 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	ALK	Tyrosine-protein kinase receptor. (1397 aa)
	AREG	Amphiregulin isoform X1. (270 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (209 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	ENSTSYP00000014591	annotation not available (71 aa)
	ENSTSYP00000015664	annotation not available (68 aa)
	GAS6	Growth arrest-specific protein 6. (440 aa)
	ALKAL1	ALK and LTK ligand 1. (129 aa)
	LTK	Tyrosine-protein kinase receptor. (780 aa)
	TGFA	Transforming growth factor alpha. (164 aa)
	GRM5	Metabotropic glutamate receptor 5. (867 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
	GHRL	Appetite-regulating hormone. (117 aa)
	ANGPT4	Angiopoietin-4. (488 aa)
	ALKAL2	ALK and LTK ligand 2. (162 aa)
	EPGN	Epigen isoform X1. (153 aa)
	ENSTSYP00000033980	annotation not available (70 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI1	EGFR	ENSTSYP00000006063	ENSTSYP00000005737	Abl interactor 1 isoform X1.	Receptor protein-tyrosine kinase.	0.400
ABI1	PAK2	ENSTSYP00000006063	ENSTSYP00000010843	Abl interactor 1 isoform X1.	Non-specific serine/threonine protein kinase.	0.660
ALK	ALKAL1	ENSTSYP00000008993	ENSTSYP00000020553	Tyrosine-protein kinase receptor.	ALK and LTK ligand 1.	0.869
ALK	ALKAL2	ENSTSYP00000008993	ENSTSYP00000028948	Tyrosine-protein kinase receptor.	ALK and LTK ligand 2.	0.889
ALK	AREG	ENSTSYP00000008993	ENSTSYP00000009215	Tyrosine-protein kinase receptor.	Amphiregulin isoform X1.	0.659
ALK	EFNA5	ENSTSYP00000008993	ENSTSYP00000000220	Tyrosine-protein kinase receptor.	ephrin-A5; Belongs to the ephrin family.	0.542
ALK	EGF	ENSTSYP00000008993	ENSTSYP00000008584	Tyrosine-protein kinase receptor.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.421
ALK	EGFR	ENSTSYP00000008993	ENSTSYP00000005737	Tyrosine-protein kinase receptor.	Receptor protein-tyrosine kinase.	0.650
ALK	ERBB4	ENSTSYP00000008993	ENSTSYP00000006840	Tyrosine-protein kinase receptor.	Receptor protein-tyrosine kinase.	0.641
ALK	GRM5	ENSTSYP00000008993	ENSTSYP00000022186	Tyrosine-protein kinase receptor.	Metabotropic glutamate receptor 5.	0.481
ALK	NRG1	ENSTSYP00000008993	ENSTSYP00000027811	Tyrosine-protein kinase receptor.	Pro-neuregulin-1, membrane-bound isoform isoform X3.	0.421
ALK	PAK2	ENSTSYP00000008993	ENSTSYP00000010843	Tyrosine-protein kinase receptor.	Non-specific serine/threonine protein kinase.	0.413
ALK	TGFA	ENSTSYP00000008993	ENSTSYP00000021904	Tyrosine-protein kinase receptor.	Transforming growth factor alpha.	0.654
ALKAL1	ALK	ENSTSYP00000020553	ENSTSYP00000008993	ALK and LTK ligand 1.	Tyrosine-protein kinase receptor.	0.869
ALKAL1	LTK	ENSTSYP00000020553	ENSTSYP00000020982	ALK and LTK ligand 1.	Tyrosine-protein kinase receptor.	0.959
ALKAL2	ALK	ENSTSYP00000028948	ENSTSYP00000008993	ALK and LTK ligand 2.	Tyrosine-protein kinase receptor.	0.889
ALKAL2	LTK	ENSTSYP00000028948	ENSTSYP00000020982	ALK and LTK ligand 2.	Tyrosine-protein kinase receptor.	0.889
ANGPT4	EGFR	ENSTSYP00000028636	ENSTSYP00000005737	Angiopoietin-4.	Receptor protein-tyrosine kinase.	0.811
ANGPT4	ERBB4	ENSTSYP00000028636	ENSTSYP00000006840	Angiopoietin-4.	Receptor protein-tyrosine kinase.	0.825
AREG	ALK	ENSTSYP00000009215	ENSTSYP00000008993	Amphiregulin isoform X1.	Tyrosine-protein kinase receptor.	0.659