STRINGSTRING
TWF2 TWF2 LOC103249303 LOC103249303 MAP1B MAP1B SMAD7 SMAD7 ENSTSYP00000022391 ENSTSYP00000022391 ZNF639 ZNF639 BDNF BDNF POU4F2 POU4F2 ENSTSYP00000021494 ENSTSYP00000021494 RASAL1 RASAL1 DBN1 DBN1 DDX49 DDX49 CDKN2AIP CDKN2AIP EXTL3 EXTL3 GOLGA4 GOLGA4 USP47 USP47 H1-5 H1-5 PSMD10 PSMD10 LOC103267547 LOC103267547 FXN FXN CSNK2A1 CSNK2A1 MAP2K5 MAP2K5 LOC103252177 LOC103252177 SEMA4D SEMA4D BRAT1 BRAT1 DNPH1 DNPH1 YAP1 YAP1 MACF1 MACF1 CPNE5 CPNE5 ENSTSYP00000016333 ENSTSYP00000016333 ADNP ADNP HDGFL2 HDGFL2 SYT2 SYT2 CDH4 CDH4 ENSTSYP00000015550 ENSTSYP00000015550 AVP AVP SRF SRF HYAL1 HYAL1 ENSTSYP00000014648 ENSTSYP00000014648 LOC103249499 LOC103249499 INO80 INO80 ERBB2 ERBB2 SLC23A2 SLC23A2 WNT3 WNT3 LOC103257309 LOC103257309 IL9 IL9 RPTOR RPTOR SUPV3L1 SUPV3L1 MTOR MTOR RPS6KA3 RPS6KA3 RIMS1 RIMS1 MFSD2A MFSD2A NCBP1 NCBP1 ARMC12 ARMC12 IGFBP1 IGFBP1 HBEGF HBEGF EDN1 EDN1 ACSL4 ACSL4 LPAR3 LPAR3 NTN1 NTN1 SMURF1 SMURF1 S100A8 S100A8 LOC103275506 LOC103275506 ITSN2 ITSN2 ADNP2 ADNP2 ADAM17 ADAM17 NOL12 NOL12 DSCAM DSCAM FN1 FN1 SLC25A33 SLC25A33 PRKN PRKN KLHL22 KLHL22 F2 F2 TRIM32 TRIM32 EGFR EGFR PLAA PLAA CPNE9 CPNE9 RUFY3 RUFY3 AKAP6 AKAP6 N6AMT1 N6AMT1 PARP2 PARP2 RNF157 RNF157 FGFR1OP FGFR1OP ADAM10 ADAM10 SYT3 SYT3 TRPC5 TRPC5 EXOSC9 EXOSC9 FAM122A FAM122A SLC44A4 SLC44A4 MMP14 MMP14 NRP1 NRP1 TEAD1 TEAD1 TRPV2 TRPV2 SPHK1 SPHK1 DERL2 DERL2 EFNA5 EFNA5 CYFIP1 CYFIP1 LOC103255951 LOC103255951 RICTOR RICTOR MUL1 MUL1 SLC9A1 SLC9A1 CACNG7 CACNG7 BMPR2 BMPR2 SFN SFN LIMK1 LIMK1 ENSTSYP00000025346 ENSTSYP00000025346 CXCL16 CXCL16 WNT3A WNT3A SFRP2 SFRP2 CDKL5 CDKL5 CIB1 CIB1 SEMA5A SEMA5A NGF NGF HPN HPN MEGF8 MEGF8 NRG1 NRG1 ENSTSYP00000028373 ENSTSYP00000028373 CYBA CYBA EXOSC4 EXOSC4 ENSTSYP00000028642 ENSTSYP00000028642 ENSTSYP00000028711 ENSTSYP00000028711 IGF1 IGF1 LOC103269764 LOC103269764 LOC103270643 LOC103270643 LOC103253551 LOC103253551 MLST8 MLST8 S100A9 S100A9 ANAPC2 ANAPC2 SDCBP SDCBP EXOSC2 EXOSC2 BCL11A BCL11A AKT1 AKT1 SYT4 SYT4 DBNL DBNL RPS6KA1 RPS6KA1 TGFB2 TGFB2 EIF4G1 EIF4G1 SEMA7A SEMA7A ZFYVE27 ZFYVE27 ENSTSYP00000032262 ENSTSYP00000032262 MTPN MTPN TAF9B TAF9B ENSTSYP00000033175 ENSTSYP00000033175 CRK CRK AVPR1A AVPR1A L1CAM L1CAM ENSTSYP00000034462 ENSTSYP00000034462 RND2 RND2 SHTN1 SHTN1 PTK2B PTK2B TGFBR1 TGFBR1 KDM2B KDM2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TWF2Twinfilin-2 isoform X3. (349 aa)
LOC103249303Synaptotagmin-17. (366 aa)
MAP1BMicrotubule-associated protein 1B isoform X1. (2382 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (211 aa)
ENSTSYP00000022391annotation not available (250 aa)
ZNF639LOW QUALITY PROTEIN: zinc finger protein 639. (370 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (328 aa)
POU4F2POU domain protein. (396 aa)
ENSTSYP00000021494annotation not available (522 aa)
RASAL1rasGAP-activating-like protein 1. (689 aa)
DBN1Drebrin. (436 aa)
DDX49Probable ATP-dependent RNA helicase DDX49 isoform X1; Belongs to the DEAD box helicase family. (477 aa)
CDKN2AIPCDKN2A-interacting protein isoform X1. (583 aa)
EXTL3Exostosin-like 3; Belongs to the glycosyltransferase 47 family. (919 aa)
GOLGA4Golgin subfamily A member 4 isoform X3. (2233 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1375 aa)
H1-5Histone H1.5. (224 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC103267547LOW QUALITY PROTEIN: zinc finger protein 639-like. (471 aa)
FXNFrataxin, mitochondrial. (135 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
MAP2K5Dual specificity mitogen-activated protein kinase kinase 5 isoform X1; Belongs to the protein kinase superfamily. (448 aa)
LOC103252177Histone H3; Belongs to the histone H3 family. (136 aa)
SEMA4Dsemaphorin-4D; Belongs to the semaphorin family. (733 aa)
BRAT1BRCA1-associated ATM activator 1. (715 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (207 aa)
YAP1Transcriptional coactivator YAP1 isoform X1. (326 aa)
MACF1Microtubule-actin cross-linking factor 1. (7492 aa)
CPNE5Copine-5 isoform X2. (593 aa)
ENSTSYP00000016333annotation not available (150 aa)
ADNPActivity-dependent neuroprotector homeobox protein. (1101 aa)
HDGFL2Hepatoma-derived growth factor-related protein 2. (548 aa)
SYT2Synaptotagmin-2 isoform X1. (419 aa)
CDH4Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (840 aa)
ENSTSYP00000015550annotation not available (171 aa)
AVPVasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (107 aa)
SRFSerum response factor isoform X1. (456 aa)
HYAL1Hyaluronidase. (435 aa)
ENSTSYP00000014648annotation not available (200 aa)
LOC103249499Drebrin-like. (162 aa)
INO80DNA helicase INO80. (1559 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
SLC23A2Solute carrier family 23 member 2. (650 aa)
WNT3Wnt family member 3. (239 aa)
LOC103257309Regulating synaptic membrane exocytosis protein 2. (461 aa)
IL9Interleukin-9. (144 aa)
RPTORRegulatory-associated protein of mTOR. (1012 aa)
SUPV3L1ATP-dependent RNA helicase SUPV3L1, mitochondrial. (788 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (729 aa)
RIMS1Regulating synaptic membrane exocytosis protein 1 isoform X17. (1191 aa)
MFSD2ASodium-dependent lysophosphatidylcholine symporter 1 isoform X1. (530 aa)
NCBP1Nuclear cap-binding protein subunit 1. (423 aa)
ARMC12Armadillo repeat-containing protein 12 isoform X1. (366 aa)
IGFBP1Insulin-like growth factor-binding protein 1. (247 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
EDN1Endothelin-1. (202 aa)
ACSL4long-chain-fatty-acid--CoA ligase 4 isoform X1. (711 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
NTN1Netrin-1. (597 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
LOC103275506Putative oncomodulin-2 isoform X1; Belongs to the parvalbumin family. (109 aa)
ITSN2Intersectin-2 isoform X1. (1662 aa)
ADNP2ADNP homeobox protein 2 isoform X2. (1125 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (824 aa)
NOL12Nucleolar protein 12. (214 aa)
DSCAMDown syndrome cell adhesion molecule. (1832 aa)
FN1Fibronectin isoform X2. (2450 aa)
SLC25A33Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
PRKNRBR-type E3 ubiquitin transferase. (220 aa)
KLHL22Kelch-like protein 22. (636 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
PLAAPhospholipase A-2-activating protein. (795 aa)
CPNE9Copine-9 isoform X1. (546 aa)
RUFY3Protein RUFY3 isoform X2. (588 aa)
AKAP6A-kinase anchor protein 6. (2242 aa)
N6AMT1hemK methyltransferase family member 2 isoform X1. (214 aa)
PARP2Poly [ADP-ribose] polymerase. (568 aa)
RNF157RING finger protein 157 isoform X2. (660 aa)
FGFR1OPFGFR1 oncogene partner. (365 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
SYT3Synaptotagmin-3. (588 aa)
TRPC5Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (632 aa)
EXOSC9Exosome complex component RRP45 isoform X2. (440 aa)
FAM122AProtein FAM122A. (332 aa)
SLC44A4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (708 aa)
MMP14Matrix metalloproteinase-14 isoform X1. (582 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (927 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X2. (426 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2 isoform X2; Belongs to the transient receptor (TC 1.A.4) family. (765 aa)
SPHK1Sphingosine kinase 1. (438 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
EFNA5ephrin-A5; Belongs to the ephrin family. (228 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
LOC103255951Regulatory-associated protein of mTOR-like. (199 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1699 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (811 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
LIMK1LIM domain kinase 1 isoform X1. (663 aa)
ENSTSYP00000025346annotation not available (194 aa)
CXCL16C-X-C motif chemokine 16. (253 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SFRP2Secreted frizzled-related protein 2. (301 aa)
CDKL5Cyclin-dependent kinase-like 5. (960 aa)
CIB1Calcium and integrin-binding protein 1 isoform X3. (191 aa)
SEMA5Asemaphorin-5A. (335 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (268 aa)
HPNSerine protease hepsin; Belongs to the peptidase S1 family. (417 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2836 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
ENSTSYP00000028373annotation not available (134 aa)
CYBACytochrome b-245 light chain. (176 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
ENSTSYP00000028642annotation not available (113 aa)
ENSTSYP00000028711annotation not available (200 aa)
IGF1Insulin-like growth factor I isoform X1. (209 aa)
LOC103269764Stromal cell-derived factor 1-like; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
LOC103270643LOW QUALITY PROTEIN: disrupted in schizophrenia 1 protein-like. (344 aa)
LOC103253551Synaptotagmin-17-like. (168 aa)
MLST8Target of rapamycin complex subunit LST8 isoform X2. (326 aa)
S100A9Protein S100; Belongs to the S-100 family. (133 aa)
ANAPC2Anaphase-promoting complex subunit 2. (577 aa)
SDCBPSyntenin-1 isoform X2. (302 aa)
EXOSC2Exosome complex component RRP4 isoform X1. (293 aa)
BCL11ALOW QUALITY PROTEIN: B-cell lymphoma/leukemia 11A-like. (834 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
SYT4Synaptotagmin-4 isoform X1. (425 aa)
DBNLDrebrin-like protein isoform X2. (430 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X5. (1608 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (666 aa)
ZFYVE27Protrudin isoform X3. (404 aa)
ENSTSYP00000032262annotation not available (99 aa)
MTPNMyotrophin. (118 aa)
TAF9BTranscription initiation factor TFIID subunit 9B isoform X1. (251 aa)
ENSTSYP00000033175annotation not available (136 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (418 aa)
L1CAMNeural cell adhesion molecule L1. (1257 aa)
ENSTSYP00000034462annotation not available (95 aa)
RND2Rho-related GTP-binding protein RhoN. (227 aa)
SHTN1Shootin-1 isoform X1. (631 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (487 aa)
KDM2BLysine-specific demethylase 2B isoform X1. (1331 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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