(55 nodes) Phagocytic vesicle membrane network (Carlito syrichta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	VAMP8	Vesicle-associated membrane protein 8. (100 aa)
	LAMP1	Lysosome-associated membrane glycoprotein 1. (411 aa)
	ATP6V0A4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
	STX4	Syntaxin-4 isoform X4; Belongs to the syntaxin family. (298 aa)
	RAB5A	Ras-related protein Rab-5A isoform X1. (215 aa)
	ATP6V0A2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (817 aa)
	RAB9B	Ras-related protein Rab-9B. (201 aa)
	RAB31	Ras-related protein Rab-31. (195 aa)
	RAB11FIP1	Rab11 family-interacting protein 1 isoform X2. (647 aa)
	CYBB	Cytochrome b-245 heavy chain isoform X1. (570 aa)
	RAB32	Ras-related protein Rab-32. (198 aa)
	RAB7A	Ras-related protein Rab-7a isoform X1. (214 aa)
	APPL2	DCC-interacting protein 13-beta isoform X1. (668 aa)
	OCRL	Inositol polyphosphate 5-phosphatase OCRL-1. (901 aa)
	INPP5B	Type II inositol 1,4,5-trisphosphate 5-phosphatase. (911 aa)
	RAB8A	RAB8A, member RAS oncogene family. (191 aa)
	DMBT1	Deleted in malignant brain tumors 1 protein. (1855 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
	TAPBP	Tapasin. (464 aa)
	RILP	Rab-interacting lysosomal protein. (377 aa)
	DNM2	Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa)
	CYBA	Cytochrome b-245 light chain. (176 aa)
	ENSTSYP00000027281	annotation not available (67 aa)
	RAB22A	Ras-related protein Rab-22A. (194 aa)
	ENSTSYP00000027127	annotation not available (486 aa)
	LOC103258166	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (153 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	RAB10	Ras-related protein Rab-10. (200 aa)
	RAB39A	Ras-related protein Rab-39A. (217 aa)
	ENSTSYP00000025139	annotation not available (467 aa)
	LAMP2	Lysosome-associated membrane glycoprotein 2 isoform X1. (412 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (900 aa)
	ATP7A	Copper-transporting ATPase 1 isoform X1. (1501 aa)
	TMEM55A	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
	VAMP7	Vesicle-associated membrane protein 7 isoform X1; Belongs to the synaptobrevin family. (220 aa)
	SYT7	Synaptotagmin 7. (659 aa)
	RAB23	Ras-related protein Rab-23. (237 aa)
	HVCN1	Voltage-gated hydrogen channel 1. (259 aa)
	ATP6V0B	V-type proton ATPase 21 kDa proteolipid subunit isoform X1; Belongs to the V-ATPase proteolipid subunit family. (236 aa)
	RAB7B	Ras-related protein Rab-7b. (199 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	ENSTSYP00000018766	annotation not available (467 aa)
	RAB8B	Ras-related protein Rab-8B. (192 aa)
	LOC103270920	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (137 aa)
	ENSTSYP00000015736	annotation not available (467 aa)
	RAB43	Ras-related protein Rab-43. (153 aa)
	RAB20	Ras-related protein Rab-20. (180 aa)
	LOC103276998	HLA class I histocompatibility antigen, B-37 alpha chain-like; Belongs to the MHC class I family. (349 aa)
	SLC11A1	Natural resistance-associated macrophage protein 1 isoform X1. (522 aa)
	RAB34	Ras-related protein Rab-34 isoform X1. (275 aa)
	ANXA3	Annexin. (323 aa)
	RAB38	Ras-related protein Rab-38. (211 aa)
	PIKFYVE	1-phosphatidylinositol 3-phosphate 5-kinase. (2099 aa)
	MCOLN1	Mucolipin-1 isoform X1. (569 aa)
	PIP4P1	Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA3	STX4	ENSTSYP00000012564	ENSTSYP00000006164	Annexin.	Syntaxin-4 isoform X4; Belongs to the syntaxin family.	0.524
APPL2	INPP5B	ENSTSYP00000003138	ENSTSYP00000005147	DCC-interacting protein 13-beta isoform X1.	Type II inositol 1,4,5-trisphosphate 5-phosphatase.	0.514
APPL2	OCRL	ENSTSYP00000003138	ENSTSYP00000004622	DCC-interacting protein 13-beta isoform X1.	Inositol polyphosphate 5-phosphatase OCRL-1.	0.514
APPL2	RAB10	ENSTSYP00000003138	ENSTSYP00000026472	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-10.	0.432
APPL2	RAB20	ENSTSYP00000003138	ENSTSYP00000015537	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-20.	0.941
APPL2	RAB22A	ENSTSYP00000003138	ENSTSYP00000027220	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-22A.	0.941
APPL2	RAB31	ENSTSYP00000003138	ENSTSYP00000000621	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-31.	0.941
APPL2	RAB39A	ENSTSYP00000003138	ENSTSYP00000025820	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-39A.	0.442
APPL2	RAB5A	ENSTSYP00000003138	ENSTSYP00000006938	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-5A isoform X1.	0.941
APPL2	RAB7A	ENSTSYP00000003138	ENSTSYP00000002138	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-7a isoform X1.	0.432
APPL2	RAB8A	ENSTSYP00000003138	ENSTSYP00000034642	DCC-interacting protein 13-beta isoform X1.	RAB8A, member RAS oncogene family.	0.432
APPL2	RAB8B	ENSTSYP00000003138	ENSTSYP00000017713	DCC-interacting protein 13-beta isoform X1.	Ras-related protein Rab-8B.	0.432
ATP6V0A2	ATP6V0A4	ENSTSYP00000007455	ENSTSYP00000005544	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.929
ATP6V0A2	ATP6V0B	ENSTSYP00000007455	ENSTSYP00000019604	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase 21 kDa proteolipid subunit isoform X1; Belongs to the V-ATPase proteolipid subunit family.	0.998
ATP6V0A2	ATP6V0C	ENSTSYP00000007455	ENSTSYP00000027001	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.992
ATP6V0A2	LOC103258166	ENSTSYP00000007455	ENSTSYP00000027054	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.992
ATP6V0A2	LOC103270920	ENSTSYP00000007455	ENSTSYP00000016034	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.992
ATP6V0A2	PIKFYVE	ENSTSYP00000007455	ENSTSYP00000011587	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	1-phosphatidylinositol 3-phosphate 5-kinase.	0.515
ATP6V0A2	RAB20	ENSTSYP00000007455	ENSTSYP00000015537	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Ras-related protein Rab-20.	0.489
ATP6V0A2	RAB22A	ENSTSYP00000007455	ENSTSYP00000027220	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Ras-related protein Rab-22A.	0.489