STRINGSTRING
IL6R IL6R BMP6 BMP6 GIP GIP SMAD2 SMAD2 NR5A2 NR5A2 DLL1 DLL1 EIF2AK3 EIF2AK3 PDPK1 PDPK1 RFX3 RFX3 DNAAF1 DNAAF1 ISL1 ISL1 LOC103265753 LOC103265753 ENSTSYP00000007785 ENSTSYP00000007785 CTNNB1 CTNNB1 NEUROD1 NEUROD1 CCDC39 CCDC39 CDK6 CDK6 PROX1 PROX1 CCDC40 CCDC40 BMP5 BMP5 ZIC3 ZIC3 CDH2 CDH2 MEIS2 MEIS2 NKX2-2 NKX2-2 SHH SHH ENSTSYP00000015007 ENSTSYP00000015007 SIDT2 SIDT2 WFS1 WFS1 ENSTSYP00000020650 ENSTSYP00000020650 GDF11 GDF11 MEN1 MEN1 FGF10 FGF10 PAX6 PAX6 ENSTSYP00000022499 ENSTSYP00000022499 WNT5A WNT5A IGF2 IGF2 ENSTSYP00000025908 ENSTSYP00000025908 BMP4 BMP4 IHH IHH BAK1 BAK1 TCF7L2 TCF7L2 ACVR2B ACVR2B ALDH1A2 ALDH1A2 MSLN MSLN HNF4A HNF4A GIPR GIPR HNF1B HNF1B LOC103256667 LOC103256667 SELENOT SELENOT SMO SMO CELA1 CELA1 PAX4 PAX4 ILDR2 ILDR2 PCSK1 PCSK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6RInterleukin-6 receptor subunit alpha. (465 aa)
BMP6Bone morphogenetic protein 6. (513 aa)
GIPGastric inhibitory polypeptide. (150 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (387 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1117 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (554 aa)
RFX3Transcription factor RFX3. (776 aa)
DNAAF1Dynein assembly factor 1, axonemal. (295 aa)
ISL1Insulin gene enhancer protein ISL-1 isoform X1. (353 aa)
LOC103265753DNA-binding protein RFX6-like. (479 aa)
ENSTSYP00000007785annotation not available (217 aa)
CTNNB1Catenin beta-1 isoform X1. (783 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
CCDC39Coiled-coil domain-containing protein 39. (942 aa)
CDK6Cyclin-dependent kinase 6. (264 aa)
PROX1Prospero homeobox protein 1. (737 aa)
CCDC40Coiled-coil domain-containing protein 40. (560 aa)
BMP5Bone morphogenetic protein 5 isoform X1. (454 aa)
ZIC3LOW QUALITY PROTEIN: zinc finger protein ZIC 3. (467 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
MEIS2Homeobox protein Meis2 isoform X1. (477 aa)
NKX2-2Homeobox protein Nkx-2.2. (273 aa)
SHHSonic hedgehog signaling molecule. (368 aa)
ENSTSYP00000015007annotation not available (536 aa)
SIDT2SID1 transmembrane family member 2 isoform X2. (843 aa)
WFS1Wolframin. (436 aa)
ENSTSYP00000020650annotation not available (103 aa)
GDF11Growth/differentiation factor 11. (258 aa)
MEN1Menin. (615 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PAX6Paired box protein Pax-6. (436 aa)
ENSTSYP00000022499annotation not available (124 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
IGF2Insulin like growth factor 2. (147 aa)
ENSTSYP00000025908annotation not available (92 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (409 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (397 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (565 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
MSLNMesothelin. (626 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (474 aa)
GIPRGastric inhibitory polypeptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (443 aa)
HNF1BHepatocyte nuclear factor 1-beta isoform X1. (557 aa)
LOC103256667Hepatocyte nuclear factor 1-alpha isoform X2. (227 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (199 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
CELA1Chymotrypsin-like elastase family member 1; Belongs to the peptidase S1 family. (256 aa)
PAX4Paired box protein Pax-4. (350 aa)
ILDR2Immunoglobulin-like domain-containing receptor 2. (455 aa)
PCSK1Neuroendocrine convertase 1 isoform X1; Belongs to the peptidase S8 family. (753 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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