(42 nodes) Adherens junction organization network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDH22	Cadherin-22; Cadherins are calcium-dependent cell adhesion proteins. (842 aa)
	VCL	Vinculin. (1122 aa)
	CDH19	Cadherin-19 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
	PLEKHA7	Pleckstrin homology domain-containing family A member 7 isoform X2. (1238 aa)
	CDHR3	Cadherin-related family member 3. (879 aa)
	INAVA	Uncharacterized protein C1orf106 homolog isoform X1. (668 aa)
	TJP1	Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1765 aa)
	CDH9	Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
	CDH8	Cadherin-8 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
	DLG5	Disks large homolog 5; Belongs to the MAGUK family. (1921 aa)
	TBCD	Tubulin-specific chaperone D. (935 aa)
	FERMT2	Fermitin family homolog 2. (664 aa)
	CDH6	Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins. (790 aa)
	CDH12	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins. (631 aa)
	FER	Tyrosine-protein kinase. (647 aa)
	CDH5	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (786 aa)
	CTNNB1	Catenin beta-1 isoform X1. (783 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	CDH10	Cadherin-10 isoform X2; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
	CDH18	Cadherin-18 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (714 aa)
	DSP	Desmoplakin isoform X1. (2849 aa)
	NUMBL	Numb-like protein. (598 aa)
	EPHA4	Ephrin type-A receptor 4 isoform X2. (949 aa)
	HIPK1	Homeodomain-interacting protein kinase 1 isoform X1. (1210 aa)
	PLEC	Plectin isoform X1. (4687 aa)
	PIP5K1C	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (698 aa)
	CDH20	Cadherin-20; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
	CDH1	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (443 aa)
	CDH11	Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
	KIFC3	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (831 aa)
	CAMSAP3	Calmodulin-regulated spectrin-associated protein 3. (1245 aa)
	SMAD7	Mothers against decapentaplegic homolog 7 isoform X1. (211 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	JAM3	LOW QUALITY PROTEIN: junctional adhesion molecule C. (310 aa)
	NUMB	Protein numb homolog. (650 aa)
	CDH24	Cadherin-24; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
	RAMP2	Receptor activity-modifying protein 2. (100 aa)
	LOC103268676	Cadherin-1-like. (413 aa)
	CDH7	Cadherin-7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
	MTSS1	Metastasis suppressor protein 1. (709 aa)
	SRC	Tyrosine-protein kinase. (542 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	CDH1	ENSTSYP00000002825	ENSTSYP00000020849	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	0.705
ADAM10	CDH10	ENSTSYP00000002825	ENSTSYP00000012020	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-10 isoform X2; Cadherins are calcium-dependent cell adhesion proteins.	0.433
ADAM10	CDH11	ENSTSYP00000002825	ENSTSYP00000021708	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.	0.424
ADAM10	CDH5	ENSTSYP00000002825	ENSTSYP00000008797	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	0.607
ADAM10	CDH6	ENSTSYP00000002825	ENSTSYP00000007772	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-6; Cadherins are calcium-dependent cell adhesion proteins.	0.433
ADAM10	CDH7	ENSTSYP00000002825	ENSTSYP00000030413	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-7; Cadherins are calcium-dependent cell adhesion proteins.	0.424
ADAM10	CDH8	ENSTSYP00000002825	ENSTSYP00000006300	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-8 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.	0.424
ADAM10	CDH9	ENSTSYP00000002825	ENSTSYP00000005518	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-9; Cadherins are calcium-dependent cell adhesion proteins.	0.407
ADAM10	EPHA4	ENSTSYP00000002825	ENSTSYP00000017651	Disintegrin and metalloproteinase domain-containing protein 10.	Ephrin type-A receptor 4 isoform X2.	0.517
ADAM10	LOC103268676	ENSTSYP00000002825	ENSTSYP00000030284	Disintegrin and metalloproteinase domain-containing protein 10.	Cadherin-1-like.	0.703
ADAM10	SRC	ENSTSYP00000002825	ENSTSYP00000033233	Disintegrin and metalloproteinase domain-containing protein 10.	Tyrosine-protein kinase.	0.442
CAMSAP3	DSP	ENSTSYP00000022653	ENSTSYP00000014816	Calmodulin-regulated spectrin-associated protein 3.	Desmoplakin isoform X1.	0.450
CAMSAP3	KIFC3	ENSTSYP00000022653	ENSTSYP00000021822	Calmodulin-regulated spectrin-associated protein 3.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.581
CAMSAP3	PLEC	ENSTSYP00000022653	ENSTSYP00000020012	Calmodulin-regulated spectrin-associated protein 3.	Plectin isoform X1.	0.450
CAMSAP3	PLEKHA7	ENSTSYP00000022653	ENSTSYP00000003328	Calmodulin-regulated spectrin-associated protein 3.	Pleckstrin homology domain-containing family A member 7 isoform X2.	0.657
CDH1	ADAM10	ENSTSYP00000020849	ENSTSYP00000002825	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Disintegrin and metalloproteinase domain-containing protein 10.	0.705
CDH1	CDH11	ENSTSYP00000020849	ENSTSYP00000021708	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.	0.588
CDH1	CDH12	ENSTSYP00000020849	ENSTSYP00000008633	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin-12; Cadherins are calcium-dependent cell adhesion proteins.	0.532
CDH1	CDH5	ENSTSYP00000020849	ENSTSYP00000008797	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins.	0.762
CDH1	CDH7	ENSTSYP00000020849	ENSTSYP00000030413	Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin-7; Cadherins are calcium-dependent cell adhesion proteins.	0.541