56 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KIF16B	Kinesin-like protein KIF16B isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1391 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (474 aa)
	RASSF2	Ras association domain-containing protein 2. (326 aa)
	AREG	Amphiregulin isoform X1. (270 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	BRAF	Serine/threonine-protein kinase B-raf. (760 aa)
	PIGR	Polymeric immunoglobulin receptor. (764 aa)
	ADAM17	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (824 aa)
	EFEMP1	EGF-containing fibulin-like extracellular matrix protein 1. (492 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1280 aa)
	GAB1	GRB2-associated-binding protein 1 isoform X1. (700 aa)
	NRG3	Pro-neuregulin-3, membrane-bound isoform isoform X2. (344 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1. (554 aa)
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	PLCE1	Phosphoinositide phospholipase C. (2303 aa)
	EREG	Proepiregulin. (167 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (116 aa)
	GAREM1	GRB2-associated and regulator of MAPK protein 1. (788 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	SOCS5	Suppressor of cytokine signaling 5 isoform X1. (515 aa)
	MVP	Major vault protein isoform X1. (895 aa)
	SOS1	Son of sevenless homolog 1 isoform X2. (441 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
	ABL1	Tyrosine-protein kinase. (1148 aa)
	BTC	Probetacellulin. (178 aa)
	REPS2	ralBP1-associated Eps domain-containing protein 2. (641 aa)
	PTK2B	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	FAM83A	Protein FAM83A. (257 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
	STUB1	E3 ubiquitin-protein ligase CHIP isoform X1. (299 aa)
	AKT1	Non-specific serine/threonine protein kinase. (393 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
	EPGN	Epigen isoform X1. (153 aa)
	PTPRR	Receptor-type tyrosine-protein phosphatase R. (355 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (898 aa)
	FAM83B	Protein FAM83B. (1011 aa)
	IQGAP1	Ras GTPase-activating-like protein IQGAP1. (1657 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
	ENSTSYP00000027585	annotation not available (82 aa)
	PTK2	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
	LOC103275563	Receptor tyrosine-protein kinase erbB-3. (169 aa)
	ENSTSYP00000023371	annotation not available (665 aa)
	TGFA	Transforming growth factor alpha. (164 aa)
	VIL1	Villin-1. (828 aa)
	GRB7	Growth factor receptor-bound protein 7 isoform X1. (531 aa)
	PTK6	Tyrosine-protein kinase. (450 aa)
	MYOC	Myocilin. (492 aa)
	SLC30A10	Zinc transporter 10. (485 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	CAMLG	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (297 aa)
	BCAR1	Breast cancer anti-estrogen resistance protein 1. (871 aa)
	DGKD	Diacylglycerol kinase. (1170 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (209 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	BCAR1	ENSTSYP00000001682	ENSTSYP00000011198	Tyrosine-protein kinase.	Breast cancer anti-estrogen resistance protein 1.	0.586
ABL1	CBL	ENSTSYP00000001682	ENSTSYP00000030023	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL.	0.989
ABL1	EGFR	ENSTSYP00000001682	ENSTSYP00000005737	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.853
ABL1	ERBB2	ENSTSYP00000001682	ENSTSYP00000014181	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.648
ABL1	ERBB4	ENSTSYP00000001682	ENSTSYP00000006840	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.598
ABL1	GRB2	ENSTSYP00000001682	ENSTSYP00000033033	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2 isoform X1.	0.989
ABL1	GRB7	ENSTSYP00000001682	ENSTSYP00000017041	Tyrosine-protein kinase.	Growth factor receptor-bound protein 7 isoform X1.	0.405
ABL1	LOC103275563	ENSTSYP00000001682	ENSTSYP00000024668	Tyrosine-protein kinase.	Receptor tyrosine-protein kinase erbB-3.	0.554
ABL1	MAPK1	ENSTSYP00000001682	ENSTSYP00000032180	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.726
ABL1	PDPK1	ENSTSYP00000001682	ENSTSYP00000006179	Tyrosine-protein kinase.	3-phosphoinositide-dependent protein kinase 1.	0.552
ABL1	PIK3CA	ENSTSYP00000001682	ENSTSYP00000003884	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.582
ABL1	PLCG1	ENSTSYP00000001682	ENSTSYP00000003818	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.493
ABL1	PTK2	ENSTSYP00000001682	ENSTSYP00000025302	Tyrosine-protein kinase.	Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.556
ABL1	PTK2B	ENSTSYP00000001682	ENSTSYP00000034695	Tyrosine-protein kinase.	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.553
ABL1	PTK6	ENSTSYP00000001682	ENSTSYP00000016516	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.667
ABL1	PTPN11	ENSTSYP00000001682	ENSTSYP00000002539	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type 11.	0.437
ABL1	SHC1	ENSTSYP00000001682	ENSTSYP00000010452	Tyrosine-protein kinase.	SHC-transforming protein 1 isoform X1.	0.949
ABL1	SOS1	ENSTSYP00000001682	ENSTSYP00000003276	Tyrosine-protein kinase.	Son of sevenless homolog 1 isoform X2.	0.440
ABL1	SRC	ENSTSYP00000001682	ENSTSYP00000033233	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.543
ABL1	STUB1	ENSTSYP00000001682	ENSTSYP00000031838	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CHIP isoform X1.	0.671