(13 nodes) Nerve growth factor signaling pathway network (Carlito syrichta)

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Your Input:
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (264 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1-like. (739 aa)
	KIDINS220	Kinase D-interacting substrate of 220 kDa isoform X1. (1772 aa)
	RAP1A	Ras-related protein Rap-1A. (184 aa)
	LOC103266825	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like. (367 aa)
	NGF	Beta-nerve growth factor; Belongs to the NGF-beta family. (268 aa)
	NTRK1	High affinity nerve growth factor receptor. (721 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2 isoform X1. (1659 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (328 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	MAGI2	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (767 aa)
	ENSTSYP00000013878	annotation not available (169 aa)
	SORT1	Sortilin. (831 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	NGF	ENSTSYP00000021524	ENSTSYP00000027110	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Beta-nerve growth factor; Belongs to the NGF-beta family.	0.951
BDNF	NTF3	ENSTSYP00000021524	ENSTSYP00000008127	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.	0.931
BDNF	NTRK1	ENSTSYP00000021524	ENSTSYP00000026521	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	High affinity nerve growth factor receptor.	0.959
BDNF	SORT1	ENSTSYP00000021524	ENSTSYP00000001853	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.	Sortilin.	0.901
ENSTSYP00000013878	KIDINS220	ENSTSYP00000013878	ENSTSYP00000029969	annotation not available	Kinase D-interacting substrate of 220 kDa isoform X1.	0.716
ENSTSYP00000013878	NTRK1	ENSTSYP00000013878	ENSTSYP00000026521	annotation not available	High affinity nerve growth factor receptor.	0.582
ENSTSYP00000013878	RAPGEF1	ENSTSYP00000013878	ENSTSYP00000034003	annotation not available	Rap guanine nucleotide exchange factor 1-like.	0.921
ENSTSYP00000013878	RAPGEF2	ENSTSYP00000013878	ENSTSYP00000026507	annotation not available	Rap guanine nucleotide exchange factor 2 isoform X1.	0.961
KIDINS220	ENSTSYP00000013878	ENSTSYP00000029969	ENSTSYP00000013878	Kinase D-interacting substrate of 220 kDa isoform X1.	annotation not available	0.716
KIDINS220	LOC103266825	ENSTSYP00000029969	ENSTSYP00000028649	Kinase D-interacting substrate of 220 kDa isoform X1.	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like.	0.866
KIDINS220	MAGI2	ENSTSYP00000029969	ENSTSYP00000018542	Kinase D-interacting substrate of 220 kDa isoform X1.	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2.	0.919
KIDINS220	NGF	ENSTSYP00000029969	ENSTSYP00000027110	Kinase D-interacting substrate of 220 kDa isoform X1.	Beta-nerve growth factor; Belongs to the NGF-beta family.	0.637
KIDINS220	NTRK1	ENSTSYP00000029969	ENSTSYP00000026521	Kinase D-interacting substrate of 220 kDa isoform X1.	High affinity nerve growth factor receptor.	0.931
KIDINS220	RAP1A	ENSTSYP00000029969	ENSTSYP00000028813	Kinase D-interacting substrate of 220 kDa isoform X1.	Ras-related protein Rap-1A.	0.716
LOC103266825	KIDINS220	ENSTSYP00000028649	ENSTSYP00000029969	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like.	Kinase D-interacting substrate of 220 kDa isoform X1.	0.866
LOC103266825	RAPGEF1	ENSTSYP00000028649	ENSTSYP00000034003	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like.	Rap guanine nucleotide exchange factor 1-like.	0.406
LOC103266825	RAPGEF2	ENSTSYP00000028649	ENSTSYP00000026507	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2-like.	Rap guanine nucleotide exchange factor 2 isoform X1.	0.905
MAGI2	KIDINS220	ENSTSYP00000018542	ENSTSYP00000029969	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2.	Kinase D-interacting substrate of 220 kDa isoform X1.	0.919
MAGI2	RAPGEF1	ENSTSYP00000018542	ENSTSYP00000034003	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2.	Rap guanine nucleotide exchange factor 1-like.	0.406
MAGI2	RAPGEF2	ENSTSYP00000018542	ENSTSYP00000026507	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2.	Rap guanine nucleotide exchange factor 2 isoform X1.	0.928