STRINGSTRING
AFP AFP ECE2 ECE2 TG TG PAPSS2 PAPSS2 HSD17B12 HSD17B12 LOC103251566 LOC103251566 SRD5A2 SRD5A2 SLC16A2 SLC16A2 DPP4 DPP4 DIO2 DIO2 AWAT2 AWAT2 REN REN CTSG CTSG PTPN11 PTPN11 ECE1 ECE1 AKR1D1 AKR1D1 ADAM10 ADAM10 CHST9 CHST9 LOC103260222 LOC103260222 GHRHR GHRHR SGPL1 SGPL1 SLC16A10 SLC16A10 RDH12 RDH12 HSD17B7 HSD17B7 CRABP1 CRABP1 LOC103267659 LOC103267659 DHRS3 DHRS3 SCPEP1 SCPEP1 CYP3A160 CYP3A160 DHRS9 DHRS9 RETSAT RETSAT HSD17B10 HSD17B10 LOC103276020 LOC103276020 CRHBP CRHBP SRD5A1 SRD5A1 ALDH1A3 ALDH1A3 CTSK CTSK RDH10 RDH10 ESR1 ESR1 MBOAT4 MBOAT4 CPQ CPQ CYP26B1 CYP26B1 DHRS2 DHRS2 ADH4 ADH4 PNPLA4 PNPLA4 DUOX1 DUOX1 PLA2G7 PLA2G7 LOC103256384 LOC103256384 CRYM CRYM CYP19A1 CYP19A1 ENPEP ENPEP CPA3 CPA3 ERO1A ERO1A FOXE1 FOXE1 BACE2 BACE2 BCO1 BCO1 LOC103252638 LOC103252638 MEP1A MEP1A TIPARP TIPARP SULT2A1 SULT2A1 HSD17B3 HSD17B3 MME MME ENSTSYP00000009240 ENSTSYP00000009240 SRD5A3 SRD5A3 CYP46A1 CYP46A1 CYP2C8 CYP2C8 TTR TTR GHR GHR PCSK6 PCSK6 PCSK5 PCSK5 ALDH1A1 ALDH1A1 HSD17B6 HSD17B6 HSD17B2 HSD17B2 SLC30A8 SLC30A8 RDH8 RDH8 DUOX2 DUOX2 HFE HFE LOC103251152 LOC103251152 LOC103272020 LOC103272020 LOC103262046 LOC103262046 CORIN CORIN CYP2C18 CYP2C18 BBS1 BBS1 RDH14 RDH14 CHST8 CHST8 DHRS11 DHRS11 CYP2D77 CYP2D77 RBP1 RBP1 SHH SHH SLC30A5 SLC30A5 CYP21A2 CYP21A2 SELENOM SELENOM EDNRB EDNRB RDH11 RDH11 LOC103273277 LOC103273277 LOC103252533 LOC103252533 LOC103272025 LOC103272025 CYP1D1 CYP1D1 SCNN1B SCNN1B PCSK2 PCSK2 CYP2W1 CYP2W1 LOC103262004 LOC103262004 CACNA1H CACNA1H ENSTSYP00000018010 ENSTSYP00000018010 CTSZ CTSZ TPO TPO SLC30A6 SLC30A6 DGAT1 DGAT1 ENSTSYP00000018650 ENSTSYP00000018650 HSD17B8 HSD17B8 STAT5B STAT5B CYP2D68 CYP2D68 ATP6AP2 ATP6AP2 DHRS12 DHRS12 CYP11B2 CYP11B2 FURIN FURIN SPP1 SPP1 SCG5 SCG5 HSD17B1 HSD17B1 CYP11A1 CYP11A1 PCSK7 PCSK7 ENSTSYP00000023135 ENSTSYP00000023135 PCSK1N PCSK1N SDR9C7 SDR9C7 PLB1 PLB1 ALDH8A1 ALDH8A1 DHCR7 DHCR7 DDO DDO DISP1 DISP1 LIPE LIPE RDH13 RDH13 LOC103272025-2 LOC103272025-2 FDX1 FDX1 RBP4 RBP4 CYP1A1 CYP1A1 ENSTSYP00000026904 ENSTSYP00000026904 LOC103274681 LOC103274681 AKR1B10 AKR1B10 IL4I1 IL4I1 ALDH1A2 ALDH1A2 SDR16C5 SDR16C5 LOC103272021 LOC103272021 ENSTSYP00000028986 ENSTSYP00000028986 CYP27C1 CYP27C1 LOC103252849 LOC103252849 CYP1A2 CYP1A2 LOC103258264 LOC103258264 RPE65 RPE65 IYD IYD CEL CEL CYP2S1 CYP2S1 TSPO TSPO AANAT AANAT LOC103251243 LOC103251243 WNT4 WNT4 CHST10 CHST10 IDE IDE MED1 MED1 DIO1 DIO1 DGAT2 DGAT2 ADH7 ADH7 PCSK1 PCSK1 RDH5 RDH5 STARD3 STARD3 AKR1B1 AKR1B1 DHRS13 DHRS13 KLK6 KLK6 LOC103261883 LOC103261883 HSD17B11 HSD17B11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFPAlpha-fetoprotein. (605 aa)
ECE2Endothelin-converting enzyme 2 isoform X2. (883 aa)
TGThyroglobulin. (2767 aa)
PAPSS2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (617 aa)
HSD17B12Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (273 aa)
LOC103251566Non-specific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (354 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase 2. (254 aa)
SLC16A2Monocarboxylate transporter 8. (535 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (733 aa)
DIO2Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (88 aa)
AWAT2acyl-CoA wax alcohol acyltransferase 2. (333 aa)
RENRenin; Belongs to the peptidase A1 family. (403 aa)
CTSGCathepsin G-like; Belongs to the peptidase S1 family. (256 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
ECE1Endothelin-converting enzyme 1 isoform X1. (770 aa)
AKR1D13-oxo-5-beta-steroid 4-dehydrogenase isoform X1. (326 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
CHST9Carbohydrate sulfotransferase. (402 aa)
LOC103260222Alcohol dehydrogenase 1C. (366 aa)
GHRHRGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (559 aa)
SLC16A10Monocarboxylate transporter 10. (241 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
HSD17B73-keto-steroid reductase isoform X1. (306 aa)
CRABP1Cellular retinoic acid-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
LOC103267659Retinol dehydrogenase 16-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (452 aa)
CYP3A160Cytochrome P450 3A5 isoform X1. (503 aa)
DHRS9Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (369 aa)
RETSATAll-trans-retinol 13,14-reductase. (302 aa)
HSD17B103-hydroxyacyl-CoA dehydrogenase type-2 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
LOC103276020UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (393 aa)
CRHBPCorticotropin-releasing factor-binding protein. (245 aa)
SRD5A13-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (254 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
CTSKCathepsin K isoform X1; Belongs to the peptidase C1 family. (329 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
MBOAT4Ghrelin O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (435 aa)
CPQCarboxypeptidase Q. (441 aa)
CYP26B1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (444 aa)
DHRS2Dehydrogenase/reductase SDR family member 2, mitochondrial isoform X2. (280 aa)
ADH4LOW QUALITY PROTEIN: alcohol dehydrogenase 4. (375 aa)
PNPLA4Patatin-like phospholipase domain-containing protein 4. (253 aa)
DUOX1Dual oxidase 1. (1526 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (444 aa)
LOC103256384Protein YIPF. (257 aa)
CRYMKetimine reductase mu-crystallin. (314 aa)
CYP19A1Aromatase; Belongs to the cytochrome P450 family. (503 aa)
ENPEPAminopeptidase. (956 aa)
CPA3Mast cell carboxypeptidase A. (417 aa)
ERO1AERO1-like protein alpha. (452 aa)
FOXE1Forkhead box protein E1. (262 aa)
BACE2Beta-secretase 2; Belongs to the peptidase A1 family. (481 aa)
BCO1LOW QUALITY PROTEIN: beta,beta-carotene 15,15'-dioxygenase. (551 aa)
LOC103252638Aldo-keto reductase family 1 member C3 homolog. (321 aa)
MEP1AMeprin A subunit. (749 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
SULT2A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa)
HSD17B3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
MMENeprilysin. (750 aa)
ENSTSYP00000009240annotation not available (338 aa)
SRD5A3Polyprenol reductase. (243 aa)
CYP46A1Cholesterol 24-hydroxylase; Belongs to the cytochrome P450 family. (460 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8. (463 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (165 aa)
GHRGrowth hormone receptor. (614 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (969 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1824 aa)
ALDH1A1Retinal dehydrogenase 1; Belongs to the aldehyde dehydrogenase family. (501 aa)
HSD17B617-beta-hydroxysteroid dehydrogenase type 6-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
SLC30A8Zinc transporter 8. (362 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
DUOX2Dual oxidase 2. (1516 aa)
HFELOW QUALITY PROTEIN: hereditary hemochromatosis protein; Belongs to the MHC class I family. (345 aa)
LOC103251152Dehydrogenase/reductase SDR family member 7 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (350 aa)
LOC103272020Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
LOC103262046Peroxisomal multifunctional enzyme type 2. (528 aa)
CORINAtrial natriuretic peptide-converting enzyme isoform X1. (1042 aa)
CYP2C18Cytochrome P450 2C18-like isoform X1; Belongs to the cytochrome P450 family. (490 aa)
BBS1Bardet-Biedl syndrome 1 protein isoform X1. (540 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (340 aa)
CHST8Carbohydrate sulfotransferase. (352 aa)
DHRS11Dehydrogenase/reductase SDR family member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa)
CYP2D77Cytochrome P450 2D17-like; Belongs to the cytochrome P450 family. (501 aa)
RBP1LOW QUALITY PROTEIN: retinol-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (213 aa)
SHHSonic hedgehog signaling molecule. (368 aa)
SLC30A5Zinc transporter 5. (764 aa)
CYP21A2Steroid 21-hydroxylase isoform X1; Belongs to the cytochrome P450 family. (496 aa)
SELENOMSelenoprotein M. (134 aa)
EDNRBEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (283 aa)
RDH11Retinol dehydrogenase 11 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
LOC103273277Cytochrome P450 2J5-like. (282 aa)
LOC103252533Retinol dehydrogenase 16 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
LOC103272025UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (393 aa)
CYP1D1Cytochrome P450 1A1-like; Belongs to the cytochrome P450 family. (514 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (648 aa)
PCSK2Neuroendocrine convertase 2. (431 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1. (334 aa)
LOC103262004Non-specific lipid-transfer protein isoform X1. (143 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1H. (2290 aa)
ENSTSYP00000018010annotation not available (209 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (302 aa)
TPOThyroid peroxidase isoform X1. (873 aa)
SLC30A6Zinc transporter 6 isoform X1. (461 aa)
DGAT1O-acyltransferase. (481 aa)
ENSTSYP00000018650annotation not available (366 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8. (259 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
CYP2D68Cytochrome P450 2D17-like isoform X1; Belongs to the cytochrome P450 family. (504 aa)
ATP6AP2Renin receptor isoform X1. (301 aa)
DHRS12Dehydrogenase/reductase SDR family member 12. (282 aa)
CYP11B2Cytochrome P450 11B2, mitochondrial; Belongs to the cytochrome P450 family. (500 aa)
FURINFurin; Belongs to the peptidase S8 family. (794 aa)
SPP1Osteopontin isoform X1. (314 aa)
SCG5Neuroendocrine protein 7B2 isoform X2. (211 aa)
HSD17B1Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (286 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
PCSK7Proprotein convertase subtilisin/kexin type 7. (786 aa)
ENSTSYP00000023135annotation not available (201 aa)
PCSK1NproSAAS. (196 aa)
SDR9C7Short-chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
PLB1Phospholipase B1, membrane-associated. (1075 aa)
ALDH8A1Aldehyde dehydrogenase family 8 member A1 isoform X1; Belongs to the aldehyde dehydrogenase family. (487 aa)
DHCR77-dehydrocholesterol reductase. (475 aa)
DDOD-aspartate oxidase. (369 aa)
DISP1Protein dispatched homolog 1. (1521 aa)
LIPEHormone-sensitive lipase. (1056 aa)
RDH13Retinol dehydrogenase 13 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (263 aa)
LOC103272025-2UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
FDX1Adrenodoxin, mitochondrial. (186 aa)
RBP4Retinol-binding protein 4. (155 aa)
CYP1A1Cytochrome P450 1A1 isoform X1; Belongs to the cytochrome P450 family. (516 aa)
ENSTSYP00000026904annotation not available (448 aa)
LOC103274681Peroxisomal multifunctional enzyme type 2-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (603 aa)
AKR1B10Aldo-keto reductase family 1 member B10 isoform X1. (316 aa)
IL4I1L-amino-acid oxidase. (486 aa)
ALDH1A2Retinal dehydrogenase 2 isoform X1; Belongs to the aldehyde dehydrogenase family. (518 aa)
SDR16C5Epidermal retinol dehydrogenase 2 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
LOC103272021Sulfotransferase; Belongs to the sulfotransferase 1 family. (295 aa)
ENSTSYP00000028986annotation not available (137 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1. (276 aa)
LOC103252849UDP-glucuronosyltransferase 2B17-like isoform X1. (530 aa)
CYP1A2Cytochrome P450 1A2; Belongs to the cytochrome P450 family. (516 aa)
LOC103258264UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (393 aa)
RPE65Retinoid isomerohydrolase. (533 aa)
IYDIodotyrosine deiodinase 1 isoform X1. (289 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (659 aa)
CYP2S1Cytochrome P450 2S1; Belongs to the cytochrome P450 family. (465 aa)
TSPOTranslocator protein. (169 aa)
AANATSerotonin N-acetyltransferase. (246 aa)
LOC103251243Dehydrogenase/reductase SDR family member 7-like isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (352 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CHST10Carbohydrate sulfotransferase. (356 aa)
IDEInsulin-degrading enzyme isoform X1; Belongs to the peptidase M16 family. (1023 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
DIO1Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (249 aa)
DGAT2Diacylglycerol O-acyltransferase 2 isoform X1. (388 aa)
ADH7Alcohol dehydrogenase class 4 mu/sigma chain. (405 aa)
PCSK1Neuroendocrine convertase 1 isoform X1; Belongs to the peptidase S8 family. (753 aa)
RDH511-cis retinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
STARD3stAR-related lipid transfer protein 3 isoform X1. (446 aa)
AKR1B1Aldose reductase isoform X1. (316 aa)
DHRS13Dehydrogenase/reductase SDR family member 13. (327 aa)
KLK6Kallikrein-6 isoform X3; Belongs to the peptidase S1 family. (245 aa)
LOC103261883Aldo-keto reductase family 1 member C3-like. (240 aa)
HSD17B11Estradiol 17-beta-dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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