4 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	CDK5	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERBB2	NRG1	ENSTSYP00000014181	ENSTSYP00000027811	Receptor protein-tyrosine kinase.	Pro-neuregulin-1, membrane-bound isoform isoform X3.	0.991
ERBB2	PIK3R1	ENSTSYP00000014181	ENSTSYP00000020998	Receptor protein-tyrosine kinase.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.984
NRG1	ERBB2	ENSTSYP00000027811	ENSTSYP00000014181	Pro-neuregulin-1, membrane-bound isoform isoform X3.	Receptor protein-tyrosine kinase.	0.991
NRG1	PIK3R1	ENSTSYP00000027811	ENSTSYP00000020998	Pro-neuregulin-1, membrane-bound isoform isoform X3.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.621
PIK3R1	ERBB2	ENSTSYP00000020998	ENSTSYP00000014181	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	Receptor protein-tyrosine kinase.	0.984
PIK3R1	NRG1	ENSTSYP00000020998	ENSTSYP00000027811	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	Pro-neuregulin-1, membrane-bound isoform isoform X3.	0.621