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HOXB5 HOXB5 EDF1 EDF1 GSTM3 GSTM3 BMPR2 BMPR2 CLIC4 CLIC4 AFDN AFDN TJP3 TJP3 VEZF1 VEZF1 MARVELD2 MARVELD2 PECAM1 PECAM1 CLDN1 CLDN1 PPP1R16B PPP1R16B HEG1 HEG1 STC1 STC1 RAP2C RAP2C EDNRB EDNRB FASN FASN COL18A1 COL18A1 HOXA13 HOXA13 ENSTSYP00000013878 ENSTSYP00000013878 TIE1 TIE1 TNMD TNMD SMAD4 SMAD4 ARHGEF26 ARHGEF26 CCM2 CCM2 MYD88 MYD88 ENSTSYP00000006680 ENSTSYP00000006680 ROBO4 ROBO4 RAPGEF3 RAPGEF3 COL22A1 COL22A1 DLL1 DLL1 TJP1 TJP1 PDPN PDPN FSTL1 FSTL1 COL15A1 COL15A1 KDR KDR PDE4D PDE4D JAG1 JAG1 F11R F11R PROX1 PROX1 NRP1 NRP1 ACVRL1 ACVRL1 MET MET HPSE HPSE RAP1B RAP1B RDX RDX EDNRA EDNRA DMD DMD PDE2A PDE2A RAP1A RAP1A ICAM1 ICAM1 NRG1 NRG1 ACVR2B ACVR2B HEY1 HEY1 RAPGEF2 RAPGEF2 ACVR1 ACVR1 NOTCH4 NOTCH4 RAPGEF1 RAPGEF1 ENSTSYP00000033676 ENSTSYP00000033676 ENSTSYP00000033667 ENSTSYP00000033667 BARX1 BARX1 NOTCH1 NOTCH1 EZR EZR MSN MSN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXB5Homeobox protein Hox-B5. (269 aa)
EDF1Endothelial differentiation-related factor 1. (134 aa)
GSTM3Glutathione S-transferase. (224 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (229 aa)
AFDNAfadin isoform X4. (1799 aa)
TJP3Tight junction protein 3. (703 aa)
VEZF1Vascular endothelial zinc finger 1 isoform X2. (517 aa)
MARVELD2MARVEL domain-containing protein 2. (559 aa)
PECAM1Platelet endothelial cell adhesion molecule. (737 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
PPP1R16BLOW QUALITY PROTEIN: protein phosphatase 1 regulatory inhibitor subunit 16B-like. (476 aa)
HEG1Protein HEG homolog 1. (138 aa)
STC1Stanniocalcin-1. (247 aa)
RAP2CRas-related protein Rap-2c. (183 aa)
EDNRBEndothelin B receptor; Belongs to the G-protein coupled receptor 1 family. (283 aa)
FASNFatty acid synthase isoform X1. (2508 aa)
COL18A1Collagen alpha-1(XVIII) chain isoform X2. (1512 aa)
HOXA13Homeobox protein Hox-A13. (209 aa)
ENSTSYP00000013878annotation not available (169 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
TNMDTenomodulin. (317 aa)
SMAD4Mothers against decapentaplegic homolog. (551 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (868 aa)
CCM2Cerebral cavernous malformations 2 protein. (465 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (321 aa)
ENSTSYP00000006680annotation not available (255 aa)
ROBO4Roundabout homolog 4. (1006 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform X2. (924 aa)
COL22A1Collagen alpha-1(XXII) chain. (1091 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
TJP1Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1765 aa)
PDPNPodoplanin. (198 aa)
FSTL1Follistatin-related protein 1. (308 aa)
COL15A1Collagen alpha-1(XV) chain. (1328 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PDE4DPhosphodiesterase. (657 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
F11RJunctional adhesion molecule A. (298 aa)
PROX1Prospero homeobox protein 1. (737 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (927 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
METHepatocyte growth factor receptor isoform X1. (1415 aa)
HPSEHeparanase. (499 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
RDXRadixin isoform X1. (604 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
DMDDystrophin isoform X2. (648 aa)
PDE2APhosphodiesterase. (935 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
ICAM1Intercellular adhesion molecule 1. (281 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2. (304 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1659 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
NOTCH4Neurogenic locus notch homolog protein 4. (1999 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1-like. (739 aa)
ENSTSYP00000033676annotation not available (300 aa)
ENSTSYP00000033667annotation not available (142 aa)
BARX1Homeobox protein BarH-like 1. (100 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
EZREzrin isoform X3. (598 aa)
MSNMoesin. (578 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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