node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACR | EDNRA | ENSTSYP00000032523 | ENSTSYP00000030870 | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. | Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.415 |
ADGRV1 | ENSTSYP00000030232 | ENSTSYP00000009926 | ENSTSYP00000030232 | G-protein coupled receptor 98; Belongs to the G-protein coupled receptor 2 family. | annotation not available | 0.933 |
ADORA2B | DRD2 | ENSTSYP00000005583 | ENSTSYP00000026813 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.798 |
ADORA2B | DRD3 | ENSTSYP00000005583 | ENSTSYP00000003137 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. | 0.635 |
ADORA2B | HRH3 | ENSTSYP00000005583 | ENSTSYP00000022952 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Histamine H3 receptor; Belongs to the G-protein coupled receptor 1 family. | 0.669 |
ADORA2B | LHCGR | ENSTSYP00000005583 | ENSTSYP00000007704 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.553 |
ADORA2B | LOC103253630 | ENSTSYP00000005583 | ENSTSYP00000016220 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Corticotropin-releasing factor receptor 1. | 0.433 |
ADORA2B | LOC103255823 | ENSTSYP00000005583 | ENSTSYP00000000108 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. | 0.961 |
ADORA2B | TSHR | ENSTSYP00000005583 | ENSTSYP00000016848 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. | 0.683 |
AKAP5 | CACNA1C | ENSTSYP00000003449 | ENSTSYP00000014796 | A-kinase anchor protein 5. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.477 |
AVPR2 | CACNA1C | ENSTSYP00000016384 | ENSTSYP00000014796 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.554 |
AVPR2 | CACNA1D | ENSTSYP00000016384 | ENSTSYP00000029265 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.554 |
AVPR2 | DRD2 | ENSTSYP00000016384 | ENSTSYP00000026813 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.406 |
AVPR2 | EDNRA | ENSTSYP00000016384 | ENSTSYP00000030870 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. | 0.489 |
AVPR2 | LOC103255823 | ENSTSYP00000016384 | ENSTSYP00000000108 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Guanine nucleotide-binding protein G(S) subunit alpha isoform X2. | 0.990 |
CACNA1C | AKAP5 | ENSTSYP00000014796 | ENSTSYP00000003449 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | A-kinase anchor protein 5. | 0.477 |
CACNA1C | AVPR2 | ENSTSYP00000014796 | ENSTSYP00000016384 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.554 |
CACNA1C | CACNA1D | ENSTSYP00000014796 | ENSTSYP00000029265 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | 0.986 |
CACNA1C | ORAI1 | ENSTSYP00000014796 | ENSTSYP00000024006 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | Calcium release-activated calcium channel protein 1 isoform X2. | 0.479 |
CACNA1C | STIM1 | ENSTSYP00000014796 | ENSTSYP00000025414 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. | Stromal interaction molecule 1 isoform X1. | 0.576 |