(34 nodes) Negative regulation of smoothened signaling pathway network (Carlito syrichta)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	ENSTSYP00000014192	annotation not available (88 aa)
	GPR161	G-protein coupled receptor 161 isoform X1; Belongs to the G-protein coupled receptor 1 family. (549 aa)
	IFT172	Intraflagellar transport protein 172 homolog. (1749 aa)
	IFT122	Intraflagellar transport protein 122 homolog isoform X2. (1262 aa)
	VCP	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa)
	KCTD21	BTB/POZ domain-containing protein KCTD21. (260 aa)
	GLI3	LOW QUALITY PROTEIN: transcriptional activator GLI3. (1533 aa)
	GLIS2	Zinc finger protein GLIS2. (524 aa)
	RFX4	Transcription factor RFX4 isoform X1. (745 aa)
	ENPP1	Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (925 aa)
	HHIP	Hedgehog-interacting protein. (700 aa)
	SERPINE2	Glia-derived nexin; Belongs to the serpin family. (408 aa)
	CUNH16orf52	Uncharacterized protein C16orf52 homolog. (89 aa)
	PTCH1	Protein patched homolog 1. (1318 aa)
	GPC3	Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (490 aa)
	RB1	Retinoblastoma-associated protein. (929 aa)
	CD3E	T-cell surface glycoprotein CD3 epsilon chain. (178 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (398 aa)
	KCTD6	BTB/POZ domain-containing protein KCTD6 isoform X1. (237 aa)
	ENSTSYP00000034326	annotation not available (235 aa)
	ENSTSYP00000028505	annotation not available (242 aa)
	LOC103267945	Receptor of activated protein C kinase 1-like. (223 aa)
	GPR37L1	Prosaposin receptor GPR37L1 isoform X1. (481 aa)
	MEGF8	Multiple epidermal growth factor-like domains protein 8. (2836 aa)
	GLI1	LOW QUALITY PROTEIN: zinc finger protein GLI1. (1105 aa)
	LOC103256196	LOW QUALITY PROTEIN: receptor of activated protein C kinase 1-like. (305 aa)
	PTCH2	Protein patched homolog 2. (1207 aa)
	SUFU	Suppressor of fused homolog. (511 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform X1. (589 aa)
	HERC4	Probable E3 ubiquitin-protein ligase HERC4 isoform X1. (1057 aa)
	MGRN1	E3 ubiquitin-protein ligase MGRN1 isoform X1. (579 aa)
	ENSTSYP00000018559	annotation not available (259 aa)
	ULK3	Serine/threonine-protein kinase ULK3. (472 aa)
	ENSTSYP00000017154	annotation not available (93 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	GLI1	ENSTSYP00000022052	ENSTSYP00000025118	F-box/WD repeat-containing protein 1A isoform X1.	LOW QUALITY PROTEIN: zinc finger protein GLI1.	0.956
BTRC	GLI3	ENSTSYP00000022052	ENSTSYP00000008660	F-box/WD repeat-containing protein 1A isoform X1.	LOW QUALITY PROTEIN: transcriptional activator GLI3.	0.958
BTRC	SUFU	ENSTSYP00000022052	ENSTSYP00000022397	F-box/WD repeat-containing protein 1A isoform X1.	Suppressor of fused homolog.	0.504
BTRC	VCP	ENSTSYP00000022052	ENSTSYP00000008855	F-box/WD repeat-containing protein 1A isoform X1.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.697
CUNH16orf52	MEGF8	ENSTSYP00000002120	ENSTSYP00000027575	Uncharacterized protein C16orf52 homolog.	Multiple epidermal growth factor-like domains protein 8.	0.572
ENSTSYP00000028505	GLI1	ENSTSYP00000028505	ENSTSYP00000025118	annotation not available	LOW QUALITY PROTEIN: zinc finger protein GLI1.	0.878
ENSTSYP00000028505	GLI3	ENSTSYP00000028505	ENSTSYP00000008660	annotation not available	LOW QUALITY PROTEIN: transcriptional activator GLI3.	0.879
ENSTSYP00000028505	GPR161	ENSTSYP00000028505	ENSTSYP00000013943	annotation not available	G-protein coupled receptor 161 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.857
ENSTSYP00000028505	IFT122	ENSTSYP00000028505	ENSTSYP00000010231	annotation not available	Intraflagellar transport protein 122 homolog isoform X2.	0.447
ENSTSYP00000028505	SUFU	ENSTSYP00000028505	ENSTSYP00000022397	annotation not available	Suppressor of fused homolog.	0.826
ENSTSYP00000028505	ULK3	ENSTSYP00000028505	ENSTSYP00000018317	annotation not available	Serine/threonine-protein kinase ULK3.	0.443
GLI1	BTRC	ENSTSYP00000025118	ENSTSYP00000022052	LOW QUALITY PROTEIN: zinc finger protein GLI1.	F-box/WD repeat-containing protein 1A isoform X1.	0.956
GLI1	ENSTSYP00000028505	ENSTSYP00000025118	ENSTSYP00000028505	LOW QUALITY PROTEIN: zinc finger protein GLI1.	annotation not available	0.878
GLI1	GLI3	ENSTSYP00000025118	ENSTSYP00000008660	LOW QUALITY PROTEIN: zinc finger protein GLI1.	LOW QUALITY PROTEIN: transcriptional activator GLI3.	0.829
GLI1	GPR161	ENSTSYP00000025118	ENSTSYP00000013943	LOW QUALITY PROTEIN: zinc finger protein GLI1.	G-protein coupled receptor 161 isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.484
GLI1	HHIP	ENSTSYP00000025118	ENSTSYP00000005510	LOW QUALITY PROTEIN: zinc finger protein GLI1.	Hedgehog-interacting protein.	0.574
GLI1	IFT122	ENSTSYP00000025118	ENSTSYP00000010231	LOW QUALITY PROTEIN: zinc finger protein GLI1.	Intraflagellar transport protein 122 homolog isoform X2.	0.702
GLI1	IFT172	ENSTSYP00000025118	ENSTSYP00000011887	LOW QUALITY PROTEIN: zinc finger protein GLI1.	Intraflagellar transport protein 172 homolog.	0.642
GLI1	PRKACB	ENSTSYP00000025118	ENSTSYP00000000346	LOW QUALITY PROTEIN: zinc finger protein GLI1.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.878
GLI1	PTCH1	ENSTSYP00000025118	ENSTSYP00000003102	LOW QUALITY PROTEIN: zinc finger protein GLI1.	Protein patched homolog 1.	0.809