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PRKD1 PRKD1 TNIK TNIK PIM2 PIM2 WNK2 WNK2 ACVR1B ACVR1B LOC110596679 LOC110596679 TEK TEK FES FES ENSTSYP00000020188 ENSTSYP00000020188 MAP4K1 MAP4K1 DDR1 DDR1 ENSTSYP00000020597 ENSTSYP00000020597 FAM20C FAM20C LTK LTK HIPK4 HIPK4 TRPM7 TRPM7 ENSTSYP00000021212 ENSTSYP00000021212 STK25 STK25 STK26 STK26 MAPK15 MAPK15 STK16 STK16 ERN1 ERN1 LCK LCK UHMK1 UHMK1 FGFR1 FGFR1 MAP3K13 MAP3K13 CAMKK2 CAMKK2 CSK CSK INSR INSR CAD CAD MARK3 MARK3 INSRR INSRR MAP3K3 MAP3K3 HCK HCK MAP3K10 MAP3K10 DAPK3 DAPK3 ENSTSYP00000024509 ENSTSYP00000024509 GRK1 GRK1 PTK2 PTK2 FGFR3 FGFR3 TRIM28 TRIM28 EPHB4 EPHB4 MAP3K11 MAP3K11 CHEK2 CHEK2 MAPKAPK5 MAPKAPK5 MARK2 MARK2 NTRK1 NTRK1 ATP13A2 ATP13A2 STK11 STK11 PIM3 PIM3 CDKL5 CDKL5 CLK4 CLK4 DAPK2 DAPK2 MYLK2 MYLK2 ULK1 ULK1 CAMK2B CAMK2B MAPK3 MAPK3 LOC103259644 LOC103259644 NEK6 NEK6 PASK PASK PDGFRB PDGFRB HTATIP2 HTATIP2 MKNK1 MKNK1 AKT1 AKT1 IRAK1 IRAK1 MAPKAPK2 MAPKAPK2 AURKA AURKA STK4 STK4 ENSTSYP00000032200 ENSTSYP00000032200 LOC103267910 LOC103267910 LOC103276437 LOC103276437 ULK3 ULK3 SMG1 SMG1 SRC SRC DYRK1B DYRK1B DYRK1A DYRK1A MUSK MUSK SRMS SRMS STK24 STK24 PTK2B PTK2B CSF1R CSF1R TAOK2 TAOK2 PIM1 PIM1 EPHA4 EPHA4 SYK SYK EPHB3 EPHB3 CDK5 CDK5 CLK3 CLK3 PEAK1 PEAK1 AATK AATK PTK6 PTK6 MINK1 MINK1 NTRK2 NTRK2 MAP3K12 MAP3K12 EPHA8 EPHA8 CAMK2D CAMK2D GSK3B GSK3B TAOK1 TAOK1 FGR FGR MEX3B MEX3B LOC103264991 LOC103264991 LOC103262133 LOC103262133 ERBB2 ERBB2 LOC103249947 LOC103249947 FYN FYN PRKD2 PRKD2 ENSTSYP00000013721 ENSTSYP00000013721 DAPK1 DAPK1 GRK7 GRK7 EEF2K EEF2K VRK1 VRK1 RIPK3 RIPK3 EIF2S1 EIF2S1 CAMK2A CAMK2A EIF2AK2 EIF2AK2 TAOK3 TAOK3 LOC103250516 LOC103250516 PRKG2 PRKG2 PIKFYVE PIKFYVE MTOR MTOR AURKB AURKB ZAP70 ZAP70 PAK2 PAK2 SIK2 SIK2 TXK TXK FLT3 FLT3 RIPK1 RIPK1 BMX BMX ROS1 ROS1 JAK2 JAK2 FGFR2 FGFR2 ENSTSYP00000009186 ENSTSYP00000009186 CDK12 CDK12 ALK ALK ATM ATM CLK2 CLK2 FER FER EIF2AK4 EIF2AK4 BTK BTK ATG101 ATG101 NLK NLK CAMK4 CAMK4 CLK1 CLK1 ERBB4 ERBB4 TNK1 TNK1 LOC103260774 LOC103260774 NEK2 NEK2 LOC103271953 LOC103271953 PDPK1 PDPK1 EIF2AK3 EIF2AK3 EGFR EGFR STK10 STK10 WNK3 WNK3 STK33 STK33 GRK5 GRK5 MAP3K9 MAP3K9 PAK1 PAK1 EPHA1 EPHA1 PDGFRA PDGFRA KIT KIT LMTK2 LMTK2 KDR KDR DDR2 DDR2 ENSTSYP00000003286 ENSTSYP00000003286 ULK2 ULK2 MELK MELK RB1CC1 RB1CC1 ATR ATR STK17B STK17B TRIM24 TRIM24 IGF1R IGF1R PINK1 PINK1 MAPKAPK3 MAPKAPK3 LRRK2 LRRK2 RIOK2 RIOK2 ABL1 ABL1 VRK2 VRK2 IRAK3 IRAK3 TSSK4 TSSK4 PTPRC PTPRC EPHB1 EPHB1 MAK MAK OXSR1 OXSR1 LYN LYN MAP3K21 MAP3K21 STK39 STK39
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
TNIKTRAF2 and NCK-interacting protein kinase. (1293 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
WNK2Serine/threonine-protein kinase WNK2. (2142 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (509 aa)
LOC110596679myosin-IIIa-like. (101 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ENSTSYP00000020188annotation not available (70 aa)
MAP4K1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (852 aa)
DDR1Epithelial discoidin domain-containing receptor 1 isoform X1. (913 aa)
ENSTSYP00000020597annotation not available (72 aa)
FAM20CExtracellular serine/threonine protein kinase FAM20C. (488 aa)
LTKTyrosine-protein kinase receptor. (780 aa)
HIPK4Homeodomain-interacting protein kinase 4. (612 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7 isoform X2. (1864 aa)
ENSTSYP00000021212annotation not available (41 aa)
STK25Serine/threonine-protein kinase 25 isoform X1. (426 aa)
STK26Serine/threonine-protein kinase 26 isoform X1. (433 aa)
MAPK15Mitogen-activated protein kinase. (277 aa)
STK16Serine/threonine-protein kinase 16 isoform X2. (305 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (949 aa)
LCKTyrosine-protein kinase. (524 aa)
UHMK1Serine/threonine-protein kinase Kist isoform X1. (460 aa)
FGFR1Fibroblast growth factor receptor. (832 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (540 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (587 aa)
CSKTyrosine-protein kinase. (450 aa)
INSRTyrosine-protein kinase receptor. (1356 aa)
CADCAD protein. (2211 aa)
MARK3Non-specific serine/threonine protein kinase. (752 aa)
INSRRTyrosine-protein kinase receptor. (1284 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (528 aa)
HCKTyrosine-protein kinase. (546 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (891 aa)
DAPK3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (280 aa)
ENSTSYP00000024509annotation not available (352 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (465 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
FGFR3Fibroblast growth factor receptor. (745 aa)
TRIM28Transcription intermediary factor 1-beta isoform X1. (835 aa)
EPHB4Ephrin type-B receptor 4 isoform X1. (987 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (745 aa)
CHEK2Serine/threonine-protein kinase Chk2 isoform X1. (582 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform X1. (487 aa)
MARK2Non-specific serine/threonine protein kinase. (758 aa)
NTRK1High affinity nerve growth factor receptor. (721 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1149 aa)
STK11Serine/threonine-protein kinase STK11. (364 aa)
PIM3Serine/threonine-protein kinase pim-3. (209 aa)
CDKL5Cyclin-dependent kinase-like 5. (960 aa)
CLK4Dual specificity protein kinase CLK4 isoform X1; Belongs to the protein kinase superfamily. (480 aa)
DAPK2Death-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (488 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (559 aa)
ULK1Serine/threonine-protein kinase ULK1. (1051 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (666 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
LOC103259644AP2-associated protein kinase 1-like. (120 aa)
NEK6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (318 aa)
PASKLOW QUALITY PROTEIN: PAS domain-containing serine/threonine-protein kinase. (423 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
HTATIP2Oxidoreductase HTATIP2 isoform X1. (276 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (445 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (618 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (400 aa)
AURKAAurora kinase A isoform X2; Belongs to the protein kinase superfamily. (401 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
ENSTSYP00000032200annotation not available (371 aa)
LOC103267910Fibroblast growth factor receptor 2-like. (208 aa)
LOC103276437Vascular endothelial growth factor receptor 3-like. (295 aa)
ULK3Serine/threonine-protein kinase ULK3. (472 aa)
SMG1Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family. (3611 aa)
SRCTyrosine-protein kinase. (542 aa)
DYRK1BDual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1. (629 aa)
DYRK1ADual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1. (763 aa)
MUSKReceptor protein-tyrosine kinase. (741 aa)
SRMSTyrosine-protein kinase. (424 aa)
STK24Serine/threonine-protein kinase 24. (441 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (965 aa)
TAOK2Serine/threonine-protein kinase TAO2 isoform X1. (1236 aa)
PIM1Serine/threonine-protein kinase pim-1. (169 aa)
EPHA4Ephrin type-A receptor 4 isoform X2. (949 aa)
SYKTyrosine-protein kinase. (634 aa)
EPHB3Ephrin type-B receptor 3. (1049 aa)
CDK5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
CLK3Dual specificity protein kinase CLK3 isoform X1; Belongs to the protein kinase superfamily. (626 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1751 aa)
AATKSerine/threonine-protein kinase LMTK1. (1072 aa)
PTK6Tyrosine-protein kinase. (450 aa)
MINK1Misshapen-like kinase 1. (1325 aa)
NTRK2BDNF/NT-3 growth factors receptor isoform X1. (553 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
EPHA8Ephrin type-A receptor 8. (998 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (533 aa)
GSK3BGlycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (403 aa)
TAOK1Serine/threonine-protein kinase TAO1 isoform X1. (1001 aa)
FGRTyrosine-protein kinase. (526 aa)
MEX3BRNA-binding protein MEX3B. (525 aa)
LOC103264991Vascular endothelial growth factor receptor 1 isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (431 aa)
LOC103262133myosin-IIIa-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (492 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
LOC103249947Tyrosine-protein kinase receptor. (662 aa)
FYNTyrosine-protein kinase. (537 aa)
PRKD2Serine/threonine-protein kinase D2. (853 aa)
ENSTSYP00000013721annotation not available (344 aa)
DAPK1Death-associated protein kinase 1 isoform X2. (1430 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (550 aa)
EEF2KEukaryotic elongation factor 2 kinase. (724 aa)
VRK1Serine/threonine-protein kinase VRK1 isoform X5; Belongs to the protein kinase superfamily. (395 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily. (510 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase isoform X2. (532 aa)
TAOK3Serine/threonine-protein kinase TAO3 isoform X2. (898 aa)
LOC103250516Discoidin domain-containing receptor 2-like. (168 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase. (2099 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
AURKBAurora kinase B isoform X2; Belongs to the protein kinase superfamily. (345 aa)
ZAP70Tyrosine-protein kinase ZAP-70. (556 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
SIK2Serine/threonine-protein kinase SIK2. (793 aa)
TXKTyrosine-protein kinase. (524 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (980 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
BMXTyrosine-protein kinase. (653 aa)
ROS1LOW QUALITY PROTEIN: proto-oncogene tyrosine-protein kinase ROS. (1545 aa)
JAK2Tyrosine-protein kinase. (1131 aa)
FGFR2Fibroblast growth factor receptor 2 isoform X1. (615 aa)
ENSTSYP00000009186annotation not available (302 aa)
CDK12Cyclin-dependent kinase 12 isoform X2. (1481 aa)
ALKTyrosine-protein kinase receptor. (1397 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
CLK2Dual specificity protein kinase CLK2 isoform X1; Belongs to the protein kinase superfamily. (500 aa)
FERTyrosine-protein kinase. (647 aa)
EIF2AK4eIF-2-alpha kinase GCN2. (1621 aa)
BTKTyrosine-protein kinase. (659 aa)
ATG101Autophagy-related protein 101. (218 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (529 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV. (295 aa)
CLK1Dual specificity protein kinase CLK1. (512 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1 isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (667 aa)
LOC103260774AP2-associated protein kinase 1. (399 aa)
NEK2Serine/threonine-protein kinase Nek2. (445 aa)
LOC103271953Vascular endothelial growth factor receptor 1-like. (713 aa)
PDPK13-phosphoinositide-dependent protein kinase 1. (554 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3. (1117 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
STK10Serine/threonine-protein kinase 10. (901 aa)
WNK3Serine/threonine-protein kinase WNK3 isoform X1. (1793 aa)
STK33Serine/threonine-protein kinase 33; Belongs to the protein kinase superfamily. (436 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (580 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1095 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
EPHA1Ephrin type-A receptor 1. (961 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
KITMast/stem cell growth factor receptor Kit; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (953 aa)
LMTK2Serine/threonine-protein kinase LMTK2 isoform X2. (1501 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
DDR2Discoidin domain-containing receptor 2. (618 aa)
ENSTSYP00000003286annotation not available (388 aa)
ULK2Serine/threonine-protein kinase ULK2. (1040 aa)
MELKNon-specific serine/threonine protein kinase. (650 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1593 aa)
ATRSerine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2644 aa)
STK17BSerine/threonine-protein kinase 17B; Belongs to the protein kinase superfamily. (372 aa)
TRIM24Transcription intermediary factor 1-alpha. (1042 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (510 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (383 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2. (2527 aa)
RIOK2Serine/threonine-protein kinase RIO2. (552 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
VRK2Serine/threonine-protein kinase VRK2. (509 aa)
IRAK3Interleukin-1 receptor-associated kinase 3. (549 aa)
TSSK4Testis-specific serine/threonine-protein kinase 4 isoform X1. (338 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C. (601 aa)
EPHB1Ephrin type-B receptor 1. (964 aa)
MAKSerine/threonine-protein kinase MAK. (648 aa)
OXSR1Serine/threonine-protein kinase OSR1 isoform X2. (527 aa)
LYNTyrosine-protein kinase. (512 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase 21. (760 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase. (397 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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