STRINGSTRING
MED31 MED31 MORC3 MORC3 TP53INP1 TP53INP1 PAWR PAWR TRIM32 TRIM32 DACH1 DACH1 NUPR1 NUPR1 C1QL4 C1QL4 NF1 NF1 NLRC3 NLRC3 MED25 MED25 B4GALT7 B4GALT7 EMD EMD FBXO4 FBXO4 PARP10 PARP10 TP53 TP53 ENSTSYP00000026316 ENSTSYP00000026316 CDC73 CDC73 DAB2IP DAB2IP MYC MYC LZTS2 LZTS2 CAV1 CAV1 BAX BAX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
MORC3MORC family CW-type zinc finger protein 3 isoform X1. (940 aa)
TP53INP1Tumor protein p53-inducible nuclear protein 1 isoform X1. (240 aa)
PAWRPRKC apoptosis WT1 regulator protein. (224 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
DACH1LOW QUALITY PROTEIN: dachshund homolog 1. (693 aa)
NUPR1Nuclear protein 1. (99 aa)
C1QL4Complement C1q-like protein 4. (238 aa)
NF1Neurofibromin isoform X2. (2839 aa)
NLRC3NLR family CARD domain-containing protein 3. (1065 aa)
MED25Mediator of RNA polymerase II transcription subunit 25. (724 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (331 aa)
EMDEmerin. (221 aa)
FBXO4F-box only protein 4 isoform X1. (387 aa)
PARP10Poly [ADP-ribose] polymerase. (1018 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
ENSTSYP00000026316annotation not available (161 aa)
CDC73Parafibromin. (531 aa)
DAB2IPDisabled homolog 2-interacting protein. (1088 aa)
MYCMyc proto-oncogene protein. (376 aa)
LZTS2LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 2. (447 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BAXApoptosis regulator BAX isoform X1. (192 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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