(44 nodes) Axon extension network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ULK1	Serine/threonine-protein kinase ULK1. (1051 aa)
	SLC9A6	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (710 aa)
	EDN2	Endothelin-2. (178 aa)
	SEMA5B	semaphorin-5B. (1112 aa)
	EDN1	Endothelin-1. (202 aa)
	DCLK1	Serine/threonine-protein kinase DCLK1 isoform X2. (740 aa)
	LAMB2	Laminin subunit beta-2. (1798 aa)
	ALCAM	CD166 antigen isoform X1. (583 aa)
	RYK	Tyrosine-protein kinase RYK isoform X2. (529 aa)
	LOC103267212	semaphorin-5A-like; Belongs to the semaphorin family. (482 aa)
	VCL	Vinculin. (1122 aa)
	ULK2	Serine/threonine-protein kinase ULK2. (1040 aa)
	RAPH1	Ras-associated and pleckstrin homology domains-containing protein 1 isoform X1. (1113 aa)
	SLIT3	Slit homolog 3 protein. (1491 aa)
	SRF	Serum response factor isoform X1. (456 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (927 aa)
	AUTS2	Autism susceptibility gene 2 protein isoform X1. (1258 aa)
	SEMA3F	semaphorin-3F isoform X1; Belongs to the semaphorin family. (785 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	SEMA3A	semaphorin-3A; Belongs to the semaphorin family. (772 aa)
	SEMA7A	semaphorin-7A; Belongs to the semaphorin family. (666 aa)
	SSNA1	Sjoegren syndrome nuclear autoantigen 1. (119 aa)
	EDNRA	Endothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	TNR	LOW QUALITY PROTEIN: tenascin-R. (1359 aa)
	SPG11	Spatacsin isoform X1. (2441 aa)
	PLXNA3	plexin-A3. (1871 aa)
	LOC103255307	Necdin. (278 aa)
	CUNH9orf72	Guanine nucleotide exchange C9orf72 homolog. (481 aa)
	SLIT2	Slit homolog 2 protein isoform X1. (1542 aa)
	CDH4	Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (840 aa)
	CDK5	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
	DCX	Neuronal migration protein doublecortin isoform X2. (365 aa)
	SLIT1	LOW QUALITY PROTEIN: slit homolog 1 protein-like. (1014 aa)
	LHX2	LIM homeobox 2. (369 aa)
	LOC103250886	Segment polarity protein dishevelled homolog DVL-1-like. (373 aa)
	POU4F2	POU domain protein. (396 aa)
	MAP1B	Microtubule-associated protein 1B isoform X1. (2382 aa)
	CYFIP1	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (928 aa)
	LIMK1	LIM domain kinase 1 isoform X1. (663 aa)
	POU4F3	POU domain protein. (338 aa)
	EDN3	Endothelin-3 isoform X1. (214 aa)
	SEMA5A	semaphorin-5A. (335 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AUTS2	CDK5	ENSTSYP00000000862	ENSTSYP00000016921	Autism susceptibility gene 2 protein isoform X1.	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	0.489
CDH4	VCL	ENSTSYP00000015757	ENSTSYP00000000122	Cadherin-4 isoform X1; Cadherins are calcium-dependent cell adhesion proteins.	Vinculin.	0.666
CDK5	AUTS2	ENSTSYP00000016921	ENSTSYP00000000862	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	Autism susceptibility gene 2 protein isoform X1.	0.489
CDK5	LIMK1	ENSTSYP00000016921	ENSTSYP00000025223	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	LIM domain kinase 1 isoform X1.	0.459
CDK5	LOC103267212	ENSTSYP00000016921	ENSTSYP00000003140	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-5A-like; Belongs to the semaphorin family.	0.536
CDK5	MAP1B	ENSTSYP00000016921	ENSTSYP00000022923	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	Microtubule-associated protein 1B isoform X1.	0.446
CDK5	NRP1	ENSTSYP00000016921	ENSTSYP00000001617	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	Neuropilin; Belongs to the neuropilin family.	0.743
CDK5	PLXNA3	ENSTSYP00000016921	ENSTSYP00000015029	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	plexin-A3.	0.569
CDK5	SEMA3A	ENSTSYP00000016921	ENSTSYP00000032281	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-3A; Belongs to the semaphorin family.	0.712
CDK5	SEMA3F	ENSTSYP00000016921	ENSTSYP00000034418	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-3F isoform X1; Belongs to the semaphorin family.	0.464
CDK5	SEMA5A	ENSTSYP00000016921	ENSTSYP00000026947	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-5A.	0.536
CDK5	SEMA5B	ENSTSYP00000016921	ENSTSYP00000011407	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-5B.	0.536
CDK5	SEMA7A	ENSTSYP00000016921	ENSTSYP00000031792	Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-7A; Belongs to the semaphorin family.	0.464
CUNH9orf72	ULK1	ENSTSYP00000027750	ENSTSYP00000027619	Guanine nucleotide exchange C9orf72 homolog.	Serine/threonine-protein kinase ULK1.	0.969
CUNH9orf72	ULK2	ENSTSYP00000027750	ENSTSYP00000002953	Guanine nucleotide exchange C9orf72 homolog.	Serine/threonine-protein kinase ULK2.	0.938
CYFIP1	LIMK1	ENSTSYP00000023813	ENSTSYP00000025223	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	LIM domain kinase 1 isoform X1.	0.519
CYFIP1	MAP1B	ENSTSYP00000023813	ENSTSYP00000022923	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Microtubule-associated protein 1B isoform X1.	0.477
DCLK1	DCX	ENSTSYP00000009034	ENSTSYP00000017121	Serine/threonine-protein kinase DCLK1 isoform X2.	Neuronal migration protein doublecortin isoform X2.	0.901
DCX	DCLK1	ENSTSYP00000017121	ENSTSYP00000009034	Neuronal migration protein doublecortin isoform X2.	Serine/threonine-protein kinase DCLK1 isoform X2.	0.901
EDN1	EDN2	ENSTSYP00000010445	ENSTSYP00000011612	Endothelin-1.	Endothelin-2.	0.857