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COL3A1 COL3A1 ZMIZ1 ZMIZ1 NOTCH3 NOTCH3 DLL4 DLL4 APOB APOB ARID2 ARID2 ADAMTS9 ADAMTS9 CHD7 CHD7 JAG1 JAG1 PROX1 PROX1 NRP1 NRP1 SEC24B SEC24B MYLK MYLK ACVRL1 ACVRL1 PRDM1 PRDM1 EDN1 EDN1 ANGPTL3 ANGPTL3 ADGRF5 ADGRF5 TGFBR1 TGFBR1 STRA6 STRA6 ENSTSYP00000033721 ENSTSYP00000033721 NOTCH1 NOTCH1 TBX1 TBX1 EYA1 EYA1 TGFB2 TGFB2 EDNRA EDNRA TFAP2B TFAP2B LOC103250817 LOC103250817 PDGFRB PDGFRB HOXA1 HOXA1 NF1 NF1 LDLR LDLR HEY1 HEY1 BMP4 BMP4 WNT11 WNT11 TBX2 TBX2 BMPR2 BMPR2 ENG ENG PRRX1 PRRX1 SMAD7 SMAD7 FOXH1 FOXH1 EFEMP2 EFEMP2 BMPR1A BMPR1A LRP1 LRP1 NPRL3 NPRL3 SRF SRF HPGD HPGD FKBP10 FKBP10 HOXA13 HOXA13 PKD2 PKD2 MYOCD MYOCD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL3A1Collagen alpha-1(III) chain. (1466 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (973 aa)
NOTCH3Neurogenic locus notch homolog protein 3. (2169 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
APOBApolipoprotein B-100. (4537 aa)
ARID2AT-rich interactive domain-containing protein 2. (1738 aa)
ADAMTS9A disintegrin and metalloproteinase with thrombospondin motifs 9. (1932 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X1. (3018 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
PROX1Prospero homeobox protein 1. (737 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (927 aa)
SEC24BProtein transport protein Sec24B isoform X1. (1260 aa)
MYLKMyosin light chain kinase, smooth muscle isoform X1. (1917 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
PRDM1PR domain zinc finger protein 1. (825 aa)
EDN1Endothelin-1. (202 aa)
ANGPTL3Angiopoietin-related protein 3. (460 aa)
ADGRF5Adhesion G protein-coupled receptor F5 isoform X1; Belongs to the G-protein coupled receptor 2 family. (1345 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (487 aa)
STRA6Stimulated by retinoic acid gene 6 protein homolog isoform X2. (689 aa)
ENSTSYP00000033721annotation not available (206 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
TBX1T-box transcription factor TBX1. (288 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EDNRAEndothelin-1 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
TFAP2BTranscription factor AP-2-beta isoform X2. (460 aa)
LOC103250817Cartilage oligomeric matrix protein. (202 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
HOXA1Homeobox protein Hox-A1 isoform X1. (335 aa)
NF1Neurofibromin isoform X2. (2839 aa)
LDLRLow-density lipoprotein receptor. (668 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2. (304 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (409 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
TBX2T-box transcription factor TBX2. (458 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
ENGEndoglin. (578 aa)
PRRX1Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (211 aa)
FOXH1Forkhead box protein H1. (368 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2. (443 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4519 aa)
NPRL3GATOR complex protein NPRL3 isoform X2. (378 aa)
SRFSerum response factor isoform X1. (456 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)]. (234 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
HOXA13Homeobox protein Hox-A13. (209 aa)
PKD2Polycystin-2. (386 aa)
MYOCDMyocardin isoform X1. (792 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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