(13 nodes) Nitric-oxide synthase binding network (Carlito syrichta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	SCN5A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2018 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	DNM2	Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (715 aa)
	DMD	Dystrophin isoform X2. (648 aa)
	ENSTSYP00000027281	annotation not available (67 aa)
	ENSTSYP00000026316	annotation not available (161 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1140 aa)
	SNTA1	Alpha-1-syntrophin. (485 aa)
	CD74	HLA class II histocompatibility antigen gamma chain. (166 aa)
	DNM3	Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (790 aa)
	NOS1AP	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like. (448 aa)
	SLC6A4	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP2B4	SCN5A	ENSTSYP00000019145	ENSTSYP00000010476	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.525
ATP2B4	SNTA1	ENSTSYP00000019145	ENSTSYP00000016337	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Alpha-1-syntrophin.	0.552
CAV1	CAV3	ENSTSYP00000032202	ENSTSYP00000033760	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.866
CAV1	DNM2	ENSTSYP00000032202	ENSTSYP00000029307	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.702
CAV1	DNM3	ENSTSYP00000032202	ENSTSYP00000009742	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.652
CAV1	ENSTSYP00000027281	ENSTSYP00000032202	ENSTSYP00000027281	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	annotation not available	0.702
CAV3	CAV1	ENSTSYP00000033760	ENSTSYP00000032202	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.866
CAV3	DMD	ENSTSYP00000033760	ENSTSYP00000029053	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dystrophin isoform X2.	0.680
CAV3	DNM2	ENSTSYP00000033760	ENSTSYP00000029307	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.616
CAV3	DNM3	ENSTSYP00000033760	ENSTSYP00000009742	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.569
CAV3	ENSTSYP00000026316	ENSTSYP00000033760	ENSTSYP00000026316	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	annotation not available	0.867
CAV3	ENSTSYP00000027281	ENSTSYP00000033760	ENSTSYP00000027281	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	annotation not available	0.616
CAV3	SCN5A	ENSTSYP00000033760	ENSTSYP00000010476	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.648
CAV3	SNTA1	ENSTSYP00000033760	ENSTSYP00000016337	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Alpha-1-syntrophin.	0.578
CD74	DNM2	ENSTSYP00000014551	ENSTSYP00000029307	HLA class II histocompatibility antigen gamma chain.	Dynamin-2 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.500
CD74	DNM3	ENSTSYP00000014551	ENSTSYP00000009742	HLA class II histocompatibility antigen gamma chain.	Dynamin-3 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.638
CD74	ENSTSYP00000027281	ENSTSYP00000014551	ENSTSYP00000027281	HLA class II histocompatibility antigen gamma chain.	annotation not available	0.500
DMD	CAV3	ENSTSYP00000029053	ENSTSYP00000033760	Dystrophin isoform X2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.680
DMD	NOS1AP	ENSTSYP00000029053	ENSTSYP00000008595	Dystrophin isoform X2.	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like.	0.583
DMD	SNTA1	ENSTSYP00000029053	ENSTSYP00000016337	Dystrophin isoform X2.	Alpha-1-syntrophin.	0.963