STRINGSTRING
SDC1 SDC1 TRPC1 TRPC1 SLC6A1 SLC6A1 SYT12 SYT12 ACER1 ACER1 NEDD4 NEDD4 ITPR3 ITPR3 LOC103253123 LOC103253123 ITPKB ITPKB SMPD1 SMPD1 CPNE1 CPNE1 ENSTSYP00000026316 ENSTSYP00000026316 ALOX15 ALOX15 LOC103261438 LOC103261438 MNAT1 MNAT1 SYT8 SYT8 KCNMB2 KCNMB2 STIM1 STIM1 ENSTSYP00000025403 ENSTSYP00000025403 ITPKA ITPKA ECT2 ECT2 SYT2 SYT2 DPEP1 DPEP1 CPNE5 CPNE5 ALOX5AP ALOX5AP PDCD6 PDCD6 ITPKC ITPKC TTN TTN DMTN DMTN KCNMB4 KCNMB4 SYT5 SYT5 JUNB JUNB NLGN1 NLGN1 CPNE7 CPNE7 MEF2A MEF2A LOC103254788 LOC103254788 P2RX5 P2RX5 SYT6 SYT6 SYT13 SYT13 SLC25A23 SLC25A23 PRKAA1 PRKAA1 NRXN1 NRXN1 RASAL1 RASAL1 RYR2 RYR2 ENSTSYP00000021856 ENSTSYP00000021856 LOC103263091 LOC103263091 SYT7 SYT7 CAPN3 CAPN3 CLIC4 CLIC4 NCSTN NCSTN PPP3CA PPP3CA LOC103255950 LOC103255950 S100A16 S100A16 MTTP MTTP ADGRV1 ADGRV1 FOS FOS IQGAP1 IQGAP1 GIPR GIPR SYT11 SYT11 ADCY8 ADCY8 KCNB1 KCNB1 PRKAA2 PRKAA2 MCOLN1 MCOLN1 ANXA11 ANXA11 TRPC3 TRPC3 HPCA HPCA LOC103260368 LOC103260368 POLR2J POLR2J CARF CARF GPLD1 GPLD1 BRAF BRAF AHCYL1 AHCYL1 SYT9 SYT9 CPNE3 CPNE3 CACNG2 CACNG2 CPNE6 CPNE6 CPNE9 CPNE9 CRHBP CRHBP LOC103251431 LOC103251431 LOC103250483 LOC103250483 HOMER1 HOMER1 ASPH ASPH FGB FGB CASR CASR SYT3 SYT3 THBS1 THBS1 HPCAL1 HPCAL1 TSHB TSHB LOC103262499 LOC103262499 P2RX7 P2RX7 LGMN LGMN PENK PENK TRPM2 TRPM2 CPNE4 CPNE4 HNRNPD HNRNPD CPNE2 CPNE2 ADAM9 ADAM9 FGA FGA CHP2 CHP2 ENSTSYP00000034769 ENSTSYP00000034769 PTK2B PTK2B CPNE8 CPNE8 ENTPD6 ENTPD6 LOC103250736 LOC103250736 RASGRP2 RASGRP2 KCNMB3 KCNMB3 FGG FGG KCNMB1 KCNMB1 EEF2K EEF2K PKD2 PKD2 SLC25A12 SLC25A12 LOC103258177 LOC103258177 ADD1 ADD1 SLC25A24 SLC25A24 SUCNR1 SUCNR1 PLCG2 PLCG2 CAMK2D CAMK2D FOSB FOSB LOC103268605 LOC103268605 LOC103257967 LOC103257967 PEF1 PEF1 GUCA1A GUCA1A PCSK1 PCSK1 TNNT2 TNNT2 CAV1 CAV1 MEF2C MEF2C SYT4 SYT4 WNT5A WNT5A ENSTSYP00000030232 ENSTSYP00000030232 LOC103253551 LOC103253551 ALG2 ALG2 RYR3 RYR3 AQP3 AQP3 SCN5A SCN5A SLC25A13 SLC25A13
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (394 aa)
TRPC1Short transient receptor potential channel 1-like. (647 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
SYT12Synaptotagmin-12 isoform X1. (421 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (236 aa)
NEDD4E3 ubiquitin-protein ligase NEDD4 isoform X1. (1321 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2677 aa)
LOC103253123Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (327 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (819 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (618 aa)
CPNE1Copine-1 isoform X4. (538 aa)
ENSTSYP00000026316annotation not available (161 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
LOC103261438Calmodulin-like; Belongs to the calmodulin family. (130 aa)
MNAT1CDK-activating kinase assembly factor MAT1. (169 aa)
SYT8LOW QUALITY PROTEIN: synaptotagmin-8. (362 aa)
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
STIM1Stromal interaction molecule 1 isoform X1. (792 aa)
ENSTSYP00000025403annotation not available (567 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (298 aa)
ECT2Protein ECT2 isoform X2. (919 aa)
SYT2Synaptotagmin-2 isoform X1. (419 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
CPNE5Copine-5 isoform X2. (593 aa)
ALOX5APArachidonate 5-lipoxygenase-activating protein. (161 aa)
PDCD6LOW QUALITY PROTEIN: programmed cell death protein 6. (121 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (677 aa)
TTNTitin isoform X2. (5602 aa)
DMTNDematin. (395 aa)
KCNMB4Calcium-activated potassium channel subunit beta-4. (210 aa)
SYT5Synaptotagmin-5. (320 aa)
JUNBTranscription factor jun-B isoform X1. (347 aa)
NLGN1Neuroligin-1. (616 aa)
CPNE7Copine-7. (483 aa)
MEF2AMyocyte-specific enhancer factor 2A isoform X1. (498 aa)
LOC103254788Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (355 aa)
SYT6Synaptotagmin-6 isoform X1. (508 aa)
SYT13Synaptotagmin-13. (417 aa)
SLC25A23Calcium-binding mitochondrial carrier protein SCaMC-3 isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (468 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
NRXN1Neurexin-1 isoform X5. (1229 aa)
RASAL1rasGAP-activating-like protein 1. (689 aa)
RYR2Ryanodine receptor 2. (1006 aa)
ENSTSYP00000021856annotation not available (88 aa)
LOC103263091Adenylate cyclase type 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (293 aa)
SYT7Synaptotagmin 7. (659 aa)
CAPN3Calpain-3 isoform X1; Belongs to the peptidase C2 family. (821 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (229 aa)
NCSTNNicastrin isoform X1. (708 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
LOC103255950Calmodulin-like; Belongs to the calmodulin family. (131 aa)
S100A16Protein S100; Belongs to the S-100 family. (103 aa)
MTTPMicrosomal triglyceride transfer protein large subunit. (920 aa)
ADGRV1G-protein coupled receptor 98; Belongs to the G-protein coupled receptor 2 family. (5952 aa)
FOSProto-oncogene c-Fos. (379 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
GIPRGastric inhibitory polypeptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (443 aa)
SYT11Synaptotagmin-11 isoform X1. (431 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (931 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
PRKAA2Non-specific serine/threonine protein kinase. (529 aa)
MCOLN1Mucolipin-1 isoform X1. (569 aa)
ANXA11Annexin. (508 aa)
TRPC3LOW QUALITY PROTEIN: short transient receptor potential channel 3; Belongs to the transient receptor (TC 1.A.4) family. (903 aa)
HPCANeuron-specific calcium-binding protein hippocalcin. (193 aa)
LOC103260368Ryanodine receptor 3-like. (317 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (380 aa)
CARFCalcium-responsive transcription factor. (446 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
BRAFSerine/threonine-protein kinase B-raf. (760 aa)
AHCYL1Adenosylhomocysteinase. (524 aa)
SYT9Synaptotagmin-9. (491 aa)
CPNE3Copine-3. (533 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit. (316 aa)
CPNE6Copine-6 isoform X2. (607 aa)
CPNE9Copine-9 isoform X1. (546 aa)
CRHBPCorticotropin-releasing factor-binding protein. (245 aa)
LOC103251431Calcium-responsive transcription factor-like isoform X1. (295 aa)
LOC103250483calmodulin-A-like isoform X1; Belongs to the calmodulin family. (150 aa)
HOMER1Homer protein homolog 1. (366 aa)
ASPHAspartyl/asparaginyl beta-hydroxylase isoform X1. (679 aa)
FGBFibrinogen beta chain isoform X1. (492 aa)
CASRLOW QUALITY PROTEIN: extracellular calcium-sensing receptor. (1015 aa)
SYT3Synaptotagmin-3. (588 aa)
THBS1Thrombospondin-1. (1178 aa)
HPCAL1Hippocalcin-like protein 1. (193 aa)
TSHBThyroid stimulating hormone beta subunit. (139 aa)
LOC103262499Synaptotagmin-15-like. (419 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
LGMNLegumain. (433 aa)
PENKproenkephalin-A. (267 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2 isoform X1. (1573 aa)
CPNE4Copine-4. (574 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0. (202 aa)
CPNE2Copine-2. (548 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9. (795 aa)
FGAFibrinogen alpha chain. (872 aa)
CHP2Calcineurin B homologous protein 2. (196 aa)
ENSTSYP00000034769annotation not available (133 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
CPNE8Copine-8. (564 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6 isoform X1; Belongs to the GDA1/CD39 NTPase family. (477 aa)
LOC103250736Ras GTPase-activating protein 4-like. (410 aa)
RASGRP2RAS guanyl-releasing protein 2. (493 aa)
KCNMB3Calcium-activated potassium channel subunit beta-3. (273 aa)
FGGFibrinogen gamma chain isoform X1. (461 aa)
KCNMB1Calcium-activated potassium channel subunit beta-1. (191 aa)
EEF2KEukaryotic elongation factor 2 kinase. (724 aa)
PKD2Polycystin-2. (386 aa)
SLC25A12Calcium-binding mitochondrial carrier protein Aralar1 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (676 aa)
LOC103258177Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)
ADD1Alpha-adducin isoform X2. (764 aa)
SLC25A24Calcium-binding mitochondrial carrier protein SCaMC-1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (447 aa)
SUCNR1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (322 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (533 aa)
FOSBProtein fosB. (191 aa)
LOC103268605Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
LOC103257967Calmodulin-like; Belongs to the calmodulin family. (147 aa)
PEF1Peflin. (274 aa)
GUCA1AGuanylyl cyclase-activating protein 1. (164 aa)
PCSK1Neuroendocrine convertase 1 isoform X1; Belongs to the peptidase S8 family. (753 aa)
TNNT2Troponin T, cardiac muscle isoform X3. (301 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
SYT4Synaptotagmin-4 isoform X1. (425 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ENSTSYP00000030232annotation not available (333 aa)
LOC103253551Synaptotagmin-17-like. (168 aa)
ALG2Alpha-1,3/1,6-mannosyltransferase ALG2. (418 aa)
RYR3Ryanodine receptor 3 isoform X1. (2916 aa)
AQP3Aquaporin-3 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2018 aa)
SLC25A13Calcium-binding mitochondrial carrier protein Aralar2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (729 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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