STRINGSTRING
OSBPL8 OSBPL8 HCLS1 HCLS1 IAPP IAPP HBEGF HBEGF ANGPT1 ANGPT1 CASS4 CASS4 CCL19 CCL19 EGF EGF MFHAS1 MFHAS1 ENSTSYP00000007785 ENSTSYP00000007785 FERMT2 FERMT2 THPO THPO RET RET CALCR CALCR CCL21 CCL21 RTN4 RTN4 EGFR EGFR CHI3L1 CHI3L1 C1QBP C1QBP NTS NTS CX3CR1 CX3CR1 PIK3CA PIK3CA PTPRJ PTPRJ TNFAIP8L3 TNFAIP8L3 THBS1 THBS1 IGF1R IGF1R LOC103265522 LOC103265522 GFRAL GFRAL HPSE HPSE XBP1 XBP1 IL18 IL18 LOC103250673 LOC103250673 F3 F3 F10 F10 MEIS3 MEIS3 CD28 CD28 MYOC MYOC ENSTSYP00000015305 ENSTSYP00000015305 C1QTNF6 C1QTNF6 PARK7 PARK7 MC1R MC1R MTDH MTDH GAS6 GAS6 RAMP3 RAMP3 CX3CL1 CX3CL1 AXL AXL LIN28A LIN28A PINK1 PINK1 TEK TEK ENSTSYP00000020437 ENSTSYP00000020437 OSM OSM NRXN1 NRXN1 RASD2 RASD2 BAG4 BAG4 MYDGF MYDGF FGFR1 FGFR1 PIK3CG PIK3CG INSR INSR ENG ENG RICTOR RICTOR CCR7 CCR7 IGF2 IGF2 PTK2 PTK2 TNFSF11 TNFSF11 P2RX4 P2RX4 CSF3 CSF3 C1QTNF12 C1QTNF12 GATA3 GATA3 PHB PHB SEMA5A SEMA5A TNF TNF TCF7L2 TCF7L2 NRG1 NRG1 MST1R MST1R PIK3R5 PIK3R5 ITGB1BP1 ITGB1BP1 STOX1 STOX1 PIK3CD PIK3CD ADAM8 ADAM8 TGFB1 TGFB1 LOC103256667 LOC103256667 C1QTNF1 C1QTNF1 SRC SRC PDGFA PDGFA HIP1 HIP1 MAZ MAZ PIK3CB PIK3CB IGFBP5 IGFBP5 SPRY2 SPRY2 TGFBR1 TGFBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (889 aa)
HCLS1Hematopoietic lineage cell-specific protein. (469 aa)
IAPPIslet amyloid polypeptide. (89 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
ANGPT1Angiopoietin-1 isoform X1. (498 aa)
CASS4Cas scaffolding protein family member 4. (783 aa)
CCL19C-C motif chemokine 19. (102 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
MFHAS1Malignant fibrous histiocytoma-amplified sequence 1. (1047 aa)
ENSTSYP00000007785annotation not available (217 aa)
FERMT2Fermitin family homolog 2. (664 aa)
THPOThrombopoietin isoform X1. (359 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1092 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (492 aa)
CCL21C-C motif chemokine 21. (131 aa)
RTN4Reticulon. (1102 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
CHI3L1Chitinase-3-like protein 1; Belongs to the glycosyl hydrolase 18 family. (383 aa)
C1QBPLOW QUALITY PROTEIN: complement component 1 Q subcomponent-binding protein, mitochondrial. (279 aa)
NTSNeurotensin/neuromedin N. (170 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (377 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta. (1260 aa)
TNFAIP8L3TNF alpha induced protein 8 like 3. (204 aa)
THBS1Thrombospondin-1. (1178 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
LOC103265522N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase. (402 aa)
GFRALGDNF family receptor alpha-like. (394 aa)
HPSEHeparanase. (499 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (376 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa)
LOC103250673HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (278 aa)
F3Tissue factor. (294 aa)
F10Coagulation factor X isoform X1. (492 aa)
MEIS3Homeobox protein Meis3. (350 aa)
CD28T-cell-specific surface glycoprotein CD28 isoform X2. (221 aa)
MYOCMyocilin. (492 aa)
ENSTSYP00000015305annotation not available (177 aa)
C1QTNF6Complement C1q tumor necrosis factor-related protein 6. (266 aa)
PARK7Protein DJ-1. (189 aa)
MC1RMelanocortin 1 receptor. (357 aa)
MTDHProtein LYRIC isoform X3. (579 aa)
GAS6Growth arrest-specific protein 6. (440 aa)
RAMP3Receptor activity-modifying protein 3 isoform X2. (147 aa)
CX3CL1Fractalkine isoform X2. (402 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (894 aa)
LIN28AProtein lin-28 homolog A. (209 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (510 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
ENSTSYP00000020437annotation not available (273 aa)
OSMoncostatin-M. (251 aa)
NRXN1Neurexin-1 isoform X5. (1229 aa)
RASD2GTP-binding protein Rhes isoform X1. (266 aa)
BAG4BAG family molecular chaperone regulator 4 isoform X1. (456 aa)
MYDGFMyeloid-derived growth factor. (115 aa)
FGFR1Fibroblast growth factor receptor. (832 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1102 aa)
INSRTyrosine-protein kinase receptor. (1356 aa)
ENGEndoglin. (578 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1699 aa)
CCR7C-C chemokine receptor type 7 isoform X1; Belongs to the G-protein coupled receptor 1 family. (378 aa)
IGF2Insulin like growth factor 2. (147 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (250 aa)
P2RX4P2X purinoceptor 4 isoform X2. (388 aa)
CSF3Granulocyte colony-stimulating factor isoform X2. (204 aa)
C1QTNF12Adipolin. (300 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (436 aa)
PHBProhibitin. (272 aa)
SEMA5Asemaphorin-5A. (335 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (565 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1405 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (879 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (200 aa)
STOX1Storkhead-box protein 1. (923 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1063 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8. (801 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
LOC103256667Hepatocyte nuclear factor 1-alpha isoform X2. (227 aa)
C1QTNF1Complement C1q tumor necrosis factor-related protein 1. (280 aa)
SRCTyrosine-protein kinase. (542 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (202 aa)
HIP1Huntingtin-interacting protein 1. (1008 aa)
MAZMyc-associated zinc finger protein. (94 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X2; Belongs to the PI3/PI4-kinase family. (1070 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (272 aa)
SPRY2Protein sprouty homolog 2. (338 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (487 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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