STRINGSTRING
GFAP GFAP LYN LYN VEGFC VEGFC UFL1 UFL1 IL1B IL1B PRKCI PRKCI TSPO TSPO IL6 IL6 PLAG1 PLAG1 LOC103252205 LOC103252205 TNF TNF E2F1 E2F1 SLC7A5 SLC7A5 MECP2 MECP2 ENSTSYP00000019175 ENSTSYP00000019175 ENSTSYP00000019483 ENSTSYP00000019483 NTN1 NTN1 ENSTSYP00000022866 ENSTSYP00000022866
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GFAPGlial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (474 aa)
LYNTyrosine-protein kinase. (512 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (407 aa)
UFL1E3 UFM1-protein ligase 1 isoform X1. (793 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (598 aa)
TSPOTranslocator protein. (169 aa)
IL6Interleukin-6. (209 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (500 aa)
LOC103252205Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
E2F1Transcription factor E2F1. (350 aa)
SLC7A5Large neutral amino acids transporter small subunit 1. (491 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (510 aa)
ENSTSYP00000019175annotation not available (491 aa)
ENSTSYP00000019483annotation not available (478 aa)
NTN1Netrin-1. (597 aa)
ENSTSYP00000022866annotation not available (318 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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