STRINGSTRING
BMP4 BMP4 TNF TNF DDX5 DDX5 TGFB1 TGFB1 LOC103256667 LOC103256667 IL6 IL6 EIF4G1 EIF4G1 ENSTSYP00000031894 ENSTSYP00000031894 TERT TERT LOC103277171 LOC103277171 TRIM71 TRIM71 ENSTSYP00000007785 ENSTSYP00000007785 RIPK1 RIPK1 ZMPSTE24 ZMPSTE24 STAT3 STAT3 FMR1 FMR1 DND1 DND1 DHX9 DHX9 LIMD1 LIMD1 MAP2K1 MAP2K1 ENSTSYP00000018548 ENSTSYP00000018548 MYCN MYCN LIN28B LIN28B LIN28A LIN28A PUM2 PUM2 PUM1 PUM1 FXR1 FXR1 ZC3H10 ZC3H10 TRUB1 TRUB1 BCDIN3D BCDIN3D MAEL MAEL TIAL1 TIAL1 AJUBA AJUBA NCOR1 NCOR1 EGFR EGFR ESR1 ESR1 ZC3H12A ZC3H12A TP53 TP53 PPP3CA PPP3CA ELAVL1 ELAVL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4 isoform X1. (409 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
DDX5Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (601 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
LOC103256667Hepatocyte nuclear factor 1-alpha isoform X2. (227 aa)
IL6Interleukin-6. (209 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X5. (1608 aa)
ENSTSYP00000031894annotation not available (263 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1078 aa)
LOC103277171LOW QUALITY PROTEIN: signal transducer and activator of transcription 3-like. (248 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (584 aa)
ENSTSYP00000007785annotation not available (217 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
STAT3Signal transducer and activator of transcription 3. (444 aa)
FMR1Synaptic functional regulator FMR1 isoform X1. (632 aa)
DND1Dead end protein homolog 1. (356 aa)
DHX9ATP-dependent RNA helicase A. (1272 aa)
LIMD1LIM domain-containing protein 1. (674 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
ENSTSYP00000018548annotation not available (280 aa)
MYCNN-myc proto-oncogene protein. (253 aa)
LIN28BProtein lin-28 homolog B isoform X1. (258 aa)
LIN28AProtein lin-28 homolog A. (209 aa)
PUM2Pumilio homolog 2 isoform X3. (1062 aa)
PUM1Pumilio homolog 1 isoform X2. (1189 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X1. (662 aa)
ZC3H10Zinc finger CCCH domain-containing protein 10. (435 aa)
TRUB1Probable tRNA pseudouridine synthase 1 isoform X1. (351 aa)
BCDIN3Dpre-miRNA 5'-monophosphate methyltransferase. (293 aa)
MAELProtein maelstrom homolog isoform X1. (435 aa)
TIAL1Nucleolysin TIAR isoform X1. (384 aa)
AJUBALIM domain-containing protein ajuba. (513 aa)
NCOR1Nuclear receptor corepressor 1 isoform X8. (2437 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
ZC3H12AEndoribonuclease ZC3H12A isoform X1. (593 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ELAVL1ELAV-like protein; Belongs to the RRM elav family. (326 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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