9 items (Carlito syrichta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	BAK1	Bcl-2 homologous antagonist/killer. (211 aa)
	CHEK2	Serine/threonine-protein kinase Chk2 isoform X1. (582 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
	ADA	Adenosine deaminase. (363 aa)
	BAX	Apoptosis regulator BAX isoform X1. (192 aa)
	BCL2L11	Bcl-2-like protein 11 isoform X1. (200 aa)
	GLI3	LOW QUALITY PROTEIN: transcriptional activator GLI3. (1533 aa)
	KIFAP3	Kinesin-associated protein 3 isoform X1. (793 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAK1	BAX	ENSTSYP00000027108	ENSTSYP00000032626	Bcl-2 homologous antagonist/killer.	Apoptosis regulator BAX isoform X1.	0.947
BAK1	BCL2L11	ENSTSYP00000027108	ENSTSYP00000010594	Bcl-2 homologous antagonist/killer.	Bcl-2-like protein 11 isoform X1.	0.994
BAK1	TP53	ENSTSYP00000027108	ENSTSYP00000023752	Bcl-2 homologous antagonist/killer.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.982
BAX	BAK1	ENSTSYP00000032626	ENSTSYP00000027108	Apoptosis regulator BAX isoform X1.	Bcl-2 homologous antagonist/killer.	0.947
BAX	BCL2L11	ENSTSYP00000032626	ENSTSYP00000010594	Apoptosis regulator BAX isoform X1.	Bcl-2-like protein 11 isoform X1.	0.998
BAX	TP53	ENSTSYP00000032626	ENSTSYP00000023752	Apoptosis regulator BAX isoform X1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.925
BCL2L11	BAK1	ENSTSYP00000010594	ENSTSYP00000027108	Bcl-2-like protein 11 isoform X1.	Bcl-2 homologous antagonist/killer.	0.994
BCL2L11	BAX	ENSTSYP00000010594	ENSTSYP00000032626	Bcl-2-like protein 11 isoform X1.	Apoptosis regulator BAX isoform X1.	0.998
BCL2L11	TP53	ENSTSYP00000010594	ENSTSYP00000023752	Bcl-2-like protein 11 isoform X1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.586
CHEK2	TP53	ENSTSYP00000025718	ENSTSYP00000023752	Serine/threonine-protein kinase Chk2 isoform X1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.994
TP53	BAK1	ENSTSYP00000023752	ENSTSYP00000027108	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Bcl-2 homologous antagonist/killer.	0.982
TP53	BAX	ENSTSYP00000023752	ENSTSYP00000032626	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Apoptosis regulator BAX isoform X1.	0.925
TP53	BCL2L11	ENSTSYP00000023752	ENSTSYP00000010594	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Bcl-2-like protein 11 isoform X1.	0.586
TP53	CHEK2	ENSTSYP00000023752	ENSTSYP00000025718	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Serine/threonine-protein kinase Chk2 isoform X1.	0.994