STRINGSTRING
TRPA1 TRPA1 AQP1 AQP1 SRC SRC RNF112 RNF112 ENSTSYP00000032719 ENSTSYP00000032719 MAPK7 MAPK7 SIGMAR1 SIGMAR1 ENSTSYP00000032200 ENSTSYP00000032200 IL6 IL6 FABP1 FABP1 PCGF2 PCGF2 IL18BP IL18BP ENSTSYP00000029446 ENSTSYP00000029446 PDCD10 PDCD10 TNFAIP3 TNFAIP3 MAPK13 MAPK13 ENSTSYP00000025886 ENSTSYP00000025886 RHOB RHOB ENSTSYP00000024777 ENSTSYP00000024777 RELA RELA ERN1 ERN1 STK25 STK25 LOC103252255 LOC103252255 LOC103254788 LOC103254788 HSF1 HSF1 AXL AXL ENSTSYP00000018650 ENSTSYP00000018650 ENSTSYP00000018615 ENSTSYP00000018615 ENSTSYP00000018430 ENSTSYP00000018430 FXN FXN SMPD3 SMPD3 SETX SETX PARK7 PARK7 ECT2 ECT2 ENSTSYP00000015305 ENSTSYP00000015305 LOC103254373 LOC103254373 LOC103258177 LOC103258177 FYN FYN RIPK3 RIPK3 IMPACT IMPACT SIRT1 SIRT1 ANKZF1 ANKZF1 EDN1 EDN1 RIPK1 RIPK1 ARG1 ARG1 HDAC2 HDAC2 RPS3 RPS3 PRKCD PRKCD OSER1 OSER1 NET1 NET1 HDAC6 HDAC6 ABL1 ABL1 ZNF277 ZNF277 EZH2 EZH2 SPHK1 SPHK1 MAP3K5 MAP3K5 STAT6 STAT6 TRPM2 TRPM2 NFE2L2 NFE2L2 AIFM1 AIFM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1121 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (179 aa)
SRCTyrosine-protein kinase. (542 aa)
RNF112RING finger protein 112. (631 aa)
ENSTSYP00000032719annotation not available (172 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (813 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (134 aa)
ENSTSYP00000032200annotation not available (371 aa)
IL6Interleukin-6. (209 aa)
FABP1Fatty acid-binding protein, liver. (127 aa)
PCGF2Polycomb group RING finger protein 2. (343 aa)
IL18BPInterleukin-18-binding protein. (186 aa)
ENSTSYP00000029446annotation not available (424 aa)
PDCD10Programmed cell death protein 10. (212 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (783 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ENSTSYP00000025886annotation not available (391 aa)
RHOBRho-related GTP-binding protein RhoB isoform X1. (196 aa)
ENSTSYP00000024777annotation not available (185 aa)
RELATranscription factor p65. (519 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (949 aa)
STK25Serine/threonine-protein kinase 25 isoform X1. (426 aa)
LOC103252255Paired box protein Pax-2-like. (232 aa)
LOC103254788Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
HSF1Heat shock factor protein 1 isoform X2. (523 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (894 aa)
ENSTSYP00000018650annotation not available (366 aa)
ENSTSYP00000018615annotation not available (270 aa)
ENSTSYP00000018430annotation not available (163 aa)
FXNFrataxin, mitochondrial. (135 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
SETXProbable helicase senataxin. (849 aa)
PARK7Protein DJ-1. (189 aa)
ECT2Protein ECT2 isoform X2. (919 aa)
ENSTSYP00000015305annotation not available (177 aa)
LOC103254373BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (235 aa)
LOC103258177Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (183 aa)
FYNTyrosine-protein kinase. (537 aa)
RIPK3Receptor-interacting serine/threonine-protein kinase 3; Belongs to the protein kinase superfamily. (510 aa)
IMPACTProtein IMPACT. (307 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (729 aa)
ANKZF1Ankyrin repeat and zinc finger domain-containing protein 1 isoform X1. (725 aa)
EDN1Endothelin-1. (202 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
ARG1Arginase. (332 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (458 aa)
RPS340S ribosomal protein S3 isoform X1; Belongs to the universal ribosomal protein uS3 family. (280 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
OSER1Oxidative stress-responsive serine-rich protein 1 isoform X1. (292 aa)
NET1Neuroepithelial cell-transforming gene 1 protein isoform X1. (553 aa)
HDAC6Histone deacetylase 6. (1213 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
ZNF277Zinc finger protein 277. (456 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X2. (763 aa)
SPHK1Sphingosine kinase 1. (438 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1329 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2 isoform X1. (1573 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (591 aa)
AIFM1Apoptosis-inducing factor 1, mitochondrial isoform X1. (613 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.