STRINGSTRING
ATP7A ATP7A TP53 TP53 SLC9A1 SLC9A1 MEF2C MEF2C GFER GFER EZH2 EZH2 PLA2G4F PLA2G4F LOC103250373 LOC103250373 CDKN1B CDKN1B ENSTSYP00000023235 ENSTSYP00000023235 PLA2G4A PLA2G4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP7ACopper-transporting ATPase 1 isoform X1. (1501 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (811 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
GFERSulfhydryl oxidase. (131 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X2. (763 aa)
PLA2G4FPhospholipase A2. (849 aa)
LOC103250373E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (426 aa)
CDKN1BLOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa)
ENSTSYP00000023235annotation not available (64 aa)
PLA2G4APhospholipase A2. (749 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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