STRINGSTRING
SOX8 SOX8 GREB1 GREB1 GPC3 GPC3 CITED1 CITED1 JAG1 JAG1 PTCH1 PTCH1 ADAMTS16 ADAMTS16 ENSTSYP00000003795 ENSTSYP00000003795 LGR4 LGR4 EPCAM EPCAM DLL1 DLL1 HOXA11 HOXA11 HS2ST1 HS2ST1 AHI1 AHI1 HS3ST3A1 HS3ST3A1 GLI3 GLI3 SMAD4 SMAD4 CTNNB1 CTNNB1 NOTCH2 NOTCH2 GDNF GDNF CALB1 CALB1 DLG1 DLG1 PKD2 PKD2 SHH SHH WNT7B WNT7B CTNNBIP1 CTNNBIP1 TACSTD2 TACSTD2 FGF1 FGF1 LHX1 LHX1 LAMA5 LAMA5 OSR1 OSR1 WT1 WT1 WNK4 WNK4 LOC103252255 LOC103252255 GZF1 GZF1 WNT9B WNT9B HOXD11 HOXD11 SALL1 SALL1 WNT6 WNT6 WNT11 WNT11 WNT1 WNT1 DSPP DSPP BMP4 BMP4 GATA3 GATA3 TFAP2B TFAP2B HNF1B HNF1B KIF26B KIF26B PKD1 PKD1 LZTS2 LZTS2 WNT4 WNT4 MEF2C MEF2C HS3ST3B1 HS3ST3B1 IRX3 IRX3 EYA1 EYA1 HEYL HEYL MTSS1 MTSS1 NOTCH1 NOTCH1 ENSTSYP00000033115 ENSTSYP00000033115 TCF21 TCF21 UMOD UMOD GREB1L GREB1L TMEM59L TMEM59L BMP2 BMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOX8Transcription factor SOX-8. (316 aa)
GREB1Protein GREB1. (1952 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (490 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (221 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
PTCH1Protein patched homolog 1. (1318 aa)
ADAMTS16A disintegrin and metalloproteinase with thrombospondin motifs 16. (1164 aa)
ENSTSYP00000003795annotation not available (65 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (946 aa)
EPCAMEpithelial cell adhesion molecule. (316 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
HOXA11Homeobox protein Hox-A11. (313 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1. (334 aa)
AHI1Jouberin isoform X1. (1175 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
GLI3LOW QUALITY PROTEIN: transcriptional activator GLI3. (1533 aa)
SMAD4Mothers against decapentaplegic homolog. (551 aa)
CTNNB1Catenin beta-1 isoform X1. (783 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (2211 aa)
GDNFGlial cell line-derived neurotrophic factor isoform X3. (211 aa)
CALB1Calbindin. (261 aa)
DLG1Disks large homolog 1 isoform X5; Belongs to the MAGUK family. (460 aa)
PKD2Polycystin-2. (386 aa)
SHHSonic hedgehog signaling molecule. (368 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (325 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
LAMA5Laminin subunit alpha-5. (3488 aa)
OSR1LOW QUALITY PROTEIN: protein odd-skipped-related 1. (266 aa)
WT1Wilms tumor protein. (285 aa)
WNK4Serine/threonine-protein kinase WNK4. (1226 aa)
LOC103252255Paired box protein Pax-2-like. (232 aa)
GZF1GDNF-inducible zinc finger protein 1 isoform X1. (713 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
HOXD11Homeobox protein Hox-D11. (155 aa)
SALL1Sal-like protein 1. (1314 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (366 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DSPPDentin sialophosphoprotein. (990 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (409 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (436 aa)
TFAP2BTranscription factor AP-2-beta isoform X2. (460 aa)
HNF1BHepatocyte nuclear factor 1-beta isoform X1. (557 aa)
KIF26BKinesin-like protein KIF26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1565 aa)
PKD1LOW QUALITY PROTEIN: polycystin-1. (3908 aa)
LZTS2LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 2. (447 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (389 aa)
IRX3Iroquois-class homeodomain protein IRX-5. (433 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (328 aa)
MTSS1Metastasis suppressor protein 1. (709 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
ENSTSYP00000033115annotation not available (96 aa)
TCF21LOW QUALITY PROTEIN: transcription factor 21. (178 aa)
UMODUromodulin. (687 aa)
GREB1LGREB1-like protein. (1644 aa)
TMEM59LLOW QUALITY PROTEIN: transmembrane protein 59-like. (313 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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