STRINGSTRING
SCN5A SCN5A ATP2A2 ATP2A2 DLG1 DLG1 AKAP9 AKAP9 JUP JUP BIN1 BIN1 RYR2 RYR2 ENSTSYP00000026316 ENSTSYP00000026316 ENSTSYP00000028129 ENSTSYP00000028129 SRI SRI TRPM4 TRPM4 CACNA1C CACNA1C PKP2 PKP2 CAV1 CAV1 CAV3 CAV3 ANK2 ANK2 ENSTSYP00000034959 ENSTSYP00000034959 DSP DSP CAMK2D CAMK2D STC1 STC1 RANGRF RANGRF DSG2 DSG2 PDE4D PDE4D PDE4B PDE4B GATA4 GATA4 ATP2A1 ATP2A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2018 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1049 aa)
DLG1Disks large homolog 1 isoform X5; Belongs to the MAGUK family. (460 aa)
AKAP9A-kinase anchor protein 9 isoform X1. (3904 aa)
JUPJunction plakoglobin isoform X1. (745 aa)
BIN1Myc box-dependent-interacting protein 1. (257 aa)
RYR2Ryanodine receptor 2. (1006 aa)
ENSTSYP00000026316annotation not available (161 aa)
ENSTSYP00000028129annotation not available (195 aa)
SRISorcin. (198 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (978 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2045 aa)
PKP2Plakophilin-2. (826 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ANK2Ankyrin-2 isoform X3. (1012 aa)
ENSTSYP00000034959annotation not available (168 aa)
DSPDesmoplakin isoform X1. (2849 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4. (533 aa)
STC1Stanniocalcin-1. (247 aa)
RANGRFRan guanine nucleotide release factor isoform X1. (186 aa)
DSG2Desmoglein-2. (1118 aa)
PDE4DPhosphodiesterase. (657 aa)
PDE4BPhosphodiesterase. (736 aa)
GATA4Transcription factor GATA-4. (234 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1007 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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