39 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSTSYP00000031340	annotation not available (279 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2082 aa)
	STAG2	Cohesin subunit SA-2 isoform X1. (1268 aa)
	ENSTSYP00000016277	annotation not available (582 aa)
	ENSTSYP00000016690	annotation not available (218 aa)
	ENSTSYP00000017788	annotation not available (263 aa)
	ENSTSYP00000018099	annotation not available (120 aa)
	HSF1	Heat shock factor protein 1 isoform X2. (523 aa)
	FAM161A	Protein FAM161A isoform X1. (715 aa)
	KIF20B	Kinesin-like protein KIF20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
	EML1	Echinoderm microtubule-associated protein-like 1. (848 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1235 aa)
	CDK5RAP2	CDK5 regulatory subunit-associated protein 2. (1852 aa)
	ENSTSYP00000009405	Abnormal spindle microtubule assembly. (3463 aa)
	SPAG5	Sperm-associated antigen 5. (1168 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
	SMC6	Structural maintenance of chromosomes protein 6. (1097 aa)
	RSKR	Uncharacterized serine/threonine-protein kinase SgK494. (410 aa)
	CNTRL	Centriolin. (2330 aa)
	SMC3	Structural maintenance of chromosomes protein. (1208 aa)
	TNKS	Poly [ADP-ribose] polymerase. (1102 aa)
	GPSM2	G-protein-signaling modulator 2. (684 aa)
	PLK1	Serine/threonine-protein kinase PLK. (604 aa)
	MAPRE1	Microtubule-associated protein RP/EB family member 1 isoform X1. (268 aa)
	NIN	Ninein. (2132 aa)
	AURKB	Aurora kinase B isoform X2; Belongs to the protein kinase superfamily. (345 aa)
	RMDN1	Regulator of microtubule dynamics protein 1 isoform X1. (309 aa)
	BCCIP	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (315 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7 isoform X1. (705 aa)
	YPEL5	Protein yippee-like; Belongs to the yippee family. (121 aa)
	KATNBL1	KATNB1-like protein 1 isoform X1. (304 aa)
	FAM83D	Protein FAM83D. (556 aa)
	STAG1	Cohesin subunit SA-1 isoform X1. (1258 aa)
	ENSTSYP00000024208	annotation not available (262 aa)
	RAE1	mRNA export factor. (521 aa)
	GIT1	ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
	MAPKBP1	Mitogen-activated protein kinase-binding protein 1. (1515 aa)
	ENSTSYP00000030984	annotation not available (277 aa)
	AURKA	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily. (401 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF7	GIT1	ENSTSYP00000020248	ENSTSYP00000025387	Rho guanine nucleotide exchange factor 7 isoform X1.	ARF GTPase-activating protein GIT1 isoform X1.	0.993
AURKA	AURKB	ENSTSYP00000031337	ENSTSYP00000011517	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Aurora kinase B isoform X2; Belongs to the protein kinase superfamily.	0.861
AURKA	CDK5RAP2	ENSTSYP00000031337	ENSTSYP00000009594	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	CDK5 regulatory subunit-associated protein 2.	0.542
AURKA	CNTRL	ENSTSYP00000031337	ENSTSYP00000006092	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Centriolin.	0.542
AURKA	EML1	ENSTSYP00000031337	ENSTSYP00000010792	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Echinoderm microtubule-associated protein-like 1.	0.589
AURKA	ENSTSYP00000009405	ENSTSYP00000031337	ENSTSYP00000009405	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Abnormal spindle microtubule assembly.	0.811
AURKA	ENSTSYP00000016277	ENSTSYP00000031337	ENSTSYP00000016277	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	annotation not available	0.982
AURKA	ENSTSYP00000016690	ENSTSYP00000031337	ENSTSYP00000016690	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	annotation not available	0.768
AURKA	ENSTSYP00000024208	ENSTSYP00000031337	ENSTSYP00000024208	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	annotation not available	0.768
AURKA	ENSTSYP00000031340	ENSTSYP00000031337	ENSTSYP00000031340	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	annotation not available	0.768
AURKA	FAM83D	ENSTSYP00000031337	ENSTSYP00000023603	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Protein FAM83D.	0.499
AURKA	KATNA1	ENSTSYP00000031337	ENSTSYP00000007434	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	0.549
AURKA	KIF20B	ENSTSYP00000031337	ENSTSYP00000010917	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Kinesin-like protein KIF20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.732
AURKA	MAPRE1	ENSTSYP00000031337	ENSTSYP00000000768	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Microtubule-associated protein RP/EB family member 1 isoform X1.	0.768
AURKA	NIN	ENSTSYP00000031337	ENSTSYP00000000683	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Ninein.	0.551
AURKA	PLK1	ENSTSYP00000031337	ENSTSYP00000001235	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase PLK.	0.982
AURKA	RAE1	ENSTSYP00000031337	ENSTSYP00000024928	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	mRNA export factor.	0.454
AURKA	SMC1A	ENSTSYP00000031337	ENSTSYP00000010507	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein.	0.402
AURKA	SMC3	ENSTSYP00000031337	ENSTSYP00000004815	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein.	0.553
AURKA	SMC6	ENSTSYP00000031337	ENSTSYP00000006851	Aurora kinase A isoform X2; Belongs to the protein kinase superfamily.	Structural maintenance of chromosomes protein 6.	0.402