(65 nodes) Postsynaptic neurotransmitter receptor activity network (Carlito syrichta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	ENSTSYP00000032347	annotation not available (154 aa)
	LOC103267911	Metabotropic glutamate receptor 1. (260 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (960 aa)
	LOC103272884	Uncharacterized protein C4orf22-like. (75 aa)
	ZACN	Zinc-activated ligand-gated ion channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (411 aa)
	CUNH4orf22	Uncharacterized protein C4orf22 homolog. (81 aa)
	HTR3B	5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa)
	GRIK4	Glutamate receptor ionotropic, kainate 4. (502 aa)
	GABRQ	Gamma-aminobutyric acid receptor subunit theta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (614 aa)
	GABRA6	Gamma-aminobutyric acid receptor subunit alpha-6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
	GABRB3	Gamma-aminobutyric acid receptor subunit beta-3 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (404 aa)
	GRIN3A	Glutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
	CHRM1	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
	CHRM2	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
	GABRB1	Gamma-aminobutyric acid receptor subunit beta-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
	ANXA9	Annexin. (284 aa)
	GABRR2	Gamma-aminobutyric acid receptor subunit rho-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (466 aa)
	GABRG3	Gamma-aminobutyric acid receptor subunit gamma-3. (275 aa)
	GABRE	Gamma-aminobutyric acid receptor subunit epsilon; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (507 aa)
	CHRNA5	Neuronal acetylcholine receptor subunit alpha-5. (448 aa)
	CHRNA9	Neuronal acetylcholine receptor subunit alpha-9. (476 aa)
	GABRR1	Gamma-aminobutyric acid receptor subunit rho-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (438 aa)
	CHRNA2	Neuronal acetylcholine receptor subunit alpha-2. (428 aa)
	CHRNB4	Neuronal acetylcholine receptor subunit beta-4. (493 aa)
	GLRA2	Glycine receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (410 aa)
	GABRG1	Gamma-aminobutyric acid receptor subunit gamma-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (313 aa)
	CHRNA3	Neuronal acetylcholine receptor subunit alpha-3. (505 aa)
	CHRNB3	Neuronal acetylcholine receptor subunit beta-3. (457 aa)
	GABRA2	Gamma-aminobutyric acid receptor subunit alpha-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
	GABRB2	Gamma-aminobutyric acid receptor subunit beta-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
	DRD3	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (399 aa)
	GABRA3	Gamma-aminobutyric acid receptor subunit alpha-3 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (404 aa)
	GABRR3	Gamma-aminobutyric acid receptor subunit rho-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
	GABRA4	Gamma-aminobutyric acid receptor subunit alpha-4 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
	HTR3D	LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3D; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (415 aa)
	GRIN2D	Glutamate receptor ionotropic, NMDA 2D; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (766 aa)
	HTR3C	5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
	HTR3E	LOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 3E-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
	CHRNE	Acetylcholine receptor subunit epsilon. (455 aa)
	GLRA4	Glycine receptor subunit alpha-4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
	GRM1	LOW QUALITY PROTEIN: metabotropic glutamate receptor 1-like. (715 aa)
	CHRND	Acetylcholine receptor subunit delta isoform X1. (517 aa)
	GRIK5	Glutamate receptor ionotropic, kainate 5. (981 aa)
	GABRP	Gamma-aminobutyric acid receptor subunit pi isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
	GABRD	Gamma-aminobutyric acid receptor subunit delta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
	GRIK2	Glutamate receptor ionotropic, kainate 2. (870 aa)
	CHRNB1	Acetylcholine receptor subunit beta isoform X1. (500 aa)
	CHRNA6	Neuronal acetylcholine receptor subunit alpha-6 isoform X1. (494 aa)
	CHRNG	Acetylcholine receptor subunit gamma isoform X1. (516 aa)
	CHRNB2	Neuronal acetylcholine receptor subunit beta-2. (481 aa)
	GRM5	Metabotropic glutamate receptor 5. (867 aa)
	CHRM4	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
	HRH3	Histamine H3 receptor; Belongs to the G-protein coupled receptor 1 family. (449 aa)
	GLRA1	Glycine receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	GRID1	Glutamate receptor ionotropic, delta-1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (238 aa)
	GRIA1	Glutamate receptor 1. (773 aa)
	HTR3A	5-hydroxytryptamine receptor 3A isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (508 aa)
	CHRNA4	Neuronal acetylcholine receptor subunit alpha-4. (607 aa)
	DRD2	D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	CHRNA1	Acetylcholine receptor subunit alpha. (470 aa)
	CHRNA10	Neuronal acetylcholine receptor subunit alpha-10. (376 aa)
	GLRA3	Glycine receptor subunit alpha-3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (411 aa)
	CHRNA7	Neuronal acetylcholine receptor subunit alpha-7 isoform X1. (472 aa)
	GABRA5	Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
	GLRB	Glycine receptor subunit beta isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRM1	CHRM2	ENSTSYP00000010433	ENSTSYP00000010853	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.840
CHRM1	CHRM4	ENSTSYP00000010433	ENSTSYP00000022634	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.810
CHRM1	CHRNB2	ENSTSYP00000010433	ENSTSYP00000021367	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Neuronal acetylcholine receptor subunit beta-2.	0.455
CHRM1	DRD2	ENSTSYP00000010433	ENSTSYP00000026813	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.426
CHRM1	DRD3	ENSTSYP00000010433	ENSTSYP00000003137	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.405
CHRM1	GRM1	ENSTSYP00000010433	ENSTSYP00000007229	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	LOW QUALITY PROTEIN: metabotropic glutamate receptor 1-like.	0.834
CHRM1	GRM5	ENSTSYP00000010433	ENSTSYP00000022186	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Metabotropic glutamate receptor 5.	0.861
CHRM1	HRH3	ENSTSYP00000010433	ENSTSYP00000022952	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Histamine H3 receptor; Belongs to the G-protein coupled receptor 1 family.	0.695
CHRM1	LOC103267911	ENSTSYP00000010433	ENSTSYP00000032591	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Metabotropic glutamate receptor 1.	0.792
CHRM2	CHRM1	ENSTSYP00000010853	ENSTSYP00000010433	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.840
CHRM2	CHRM4	ENSTSYP00000010853	ENSTSYP00000022634	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.818
CHRM2	CHRNA2	ENSTSYP00000010853	ENSTSYP00000017453	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Neuronal acetylcholine receptor subunit alpha-2.	0.454
CHRM2	CHRNA5	ENSTSYP00000010853	ENSTSYP00000012811	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Neuronal acetylcholine receptor subunit alpha-5.	0.568
CHRM2	CHRNB2	ENSTSYP00000010853	ENSTSYP00000021367	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Neuronal acetylcholine receptor subunit beta-2.	0.431
CHRM2	CHRNB4	ENSTSYP00000010853	ENSTSYP00000017861	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Neuronal acetylcholine receptor subunit beta-4.	0.449
CHRM2	DRD2	ENSTSYP00000010853	ENSTSYP00000026813	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family.	0.467
CHRM2	DRD3	ENSTSYP00000010853	ENSTSYP00000003137	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	D(3) dopamine receptor; Belongs to the G-protein coupled receptor 1 family.	0.405
CHRM2	GABRA2	ENSTSYP00000010853	ENSTSYP00000002567	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Gamma-aminobutyric acid receptor subunit alpha-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.479
CHRM2	GRM1	ENSTSYP00000010853	ENSTSYP00000007229	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	LOW QUALITY PROTEIN: metabotropic glutamate receptor 1-like.	0.610
CHRM2	GRM5	ENSTSYP00000010853	ENSTSYP00000022186	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Metabotropic glutamate receptor 5.	0.610