STRINGSTRING
PYCR2 PYCR2 OTC OTC ASNS ASNS GLUD1 GLUD1 GLUL GLUL AASS AASS APIP APIP PCBD1 PCBD1 BHMT BHMT MTR MTR NOXRED1 NOXRED1 BHMT2 BHMT2 CPS1 CPS1 SRR SRR MTRR MTRR GOT1 GOT1 OAT OAT GLS GLS GLS2 GLS2 PCBD2 PCBD2 AGXT2 AGXT2 CTH CTH BCAT1 BCAT1 HAO1 HAO1 LOC103259940 LOC103259940 LGSN LGSN MTHFD1 MTHFD1 TMED8 TMED8 ENOPH1 ENOPH1 MRI1 MRI1 ENSTSYP00000013984 ENSTSYP00000013984 PHGDH PHGDH PSPH PSPH ADI1 ADI1 SDS SDS ENSTSYP00000017010 ENSTSYP00000017010 GOT2 GOT2 PYCR1 PYCR1 ILVBL ILVBL GOT1L1 GOT1L1 SHMT1 SHMT1 PLOD2 PLOD2 LOC103265367 LOC103265367 ASL ASL ENSTSYP00000021752 ENSTSYP00000021752 ENSTSYP00000022349 ENSTSYP00000022349 ALDH18A1 ALDH18A1 ENSTSYP00000022584 ENSTSYP00000022584 LOC103268502 LOC103268502 ASS1 ASS1 LOC103263043 LOC103263043 SHMT2 SHMT2 PAH PAH PYCR3 PYCR3 SDSL SDSL DHFR DHFR ENSTSYP00000027502 ENSTSYP00000027502 ENSTSYP00000028651 ENSTSYP00000028651 PSAT1 PSAT1 ASNSD1 ASNSD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PYCR2Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa)
OTCOrnithine carbamoyltransferase, mitochondrial; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (285 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing] isoform X1. (561 aa)
GLUD1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa)
GLULGlutamine synthetase. (380 aa)
AASSAlpha-aminoadipic semialdehyde synthase, mitochondrial. (926 aa)
APIPMethylthioribulose-1-phosphate dehydratase. (223 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase 1. (103 aa)
BHMTBetaine--homocysteine S-methyltransferase 1; Involved in the regulation of homocysteine metabolism. (355 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa)
NOXRED1NADP-dependent oxidoreductase domain-containing protein 1. (359 aa)
BHMT2S-methylmethionine--homocysteine S-methyltransferase BHMT2 isoform X1; Involved in the regulation of homocysteine metabolism. (363 aa)
CPS1Carbamoyl-phosphate synthase [ammonia], mitochondrial. (1506 aa)
SRRSerine racemase isoform X1. (339 aa)
MTRRMethionine synthase reductase. (703 aa)
GOT1Aspartate aminotransferase. (413 aa)
OATOrnithine aminotransferase, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
GLSGlutaminase kidney isoform, mitochondrial. (669 aa)
GLS2Glutaminase liver isoform, mitochondrial isoform X1. (591 aa)
PCBD2Pterin-4-alpha-carbinolamine dehydratase 2 isoform X1. (106 aa)
AGXT2Alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
CTHCystathionine gamma-lyase. (404 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (386 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
LOC103259940S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (282 aa)
LGSNLOW QUALITY PROTEIN: lengsin; Belongs to the glutamine synthetase family. (503 aa)
MTHFD1C-1-tetrahydrofolate synthase, cytoplasmic. (924 aa)
TMED8Protein TMED8. (456 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (233 aa)
MRI1Methylthioribose-1-phosphate isomerase; Belongs to the eIF-2B alpha/beta/delta subunits family. (222 aa)
ENSTSYP00000013984annotation not available (330 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (479 aa)
PSPHPhosphoserine phosphatase. (225 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
SDSL-serine dehydratase/L-threonine deaminase. (204 aa)
ENSTSYP00000017010annotation not available (352 aa)
GOT2Aspartate aminotransferase. (430 aa)
PYCR1Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (329 aa)
ILVBLAcetolactate synthase-like protein; Belongs to the TPP enzyme family. (632 aa)
GOT1L1Putative aspartate aminotransferase, cytoplasmic 2. (414 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (721 aa)
LOC103265367Cystathionine beta-synthase. (383 aa)
ASLArgininosuccinate lyase isoform X1. (460 aa)
ENSTSYP00000021752annotation not available (361 aa)
ENSTSYP00000022349annotation not available (941 aa)
ALDH18A1Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (795 aa)
ENSTSYP00000022584annotation not available (264 aa)
LOC103268502Cystathionine beta-synthase-like. (488 aa)
ASS1Argininosuccinate synthase. (97 aa)
LOC103263043Argininosuccinate synthase-like. (152 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
PAHPhenylalanine-4-hydroxylase. (452 aa)
PYCR3Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (284 aa)
SDSLSerine dehydratase-like. (269 aa)
DHFRDihydrofolate reductase isoform X1; Belongs to the dihydrofolate reductase family. (187 aa)
ENSTSYP00000027502annotation not available (149 aa)
ENSTSYP00000028651annotation not available (353 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
ASNSD1Asparagine synthetase domain-containing protein 1. (636 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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