STRINGSTRING
TNFSF11 TNFSF11 ENSTSYP00000025403 ENSTSYP00000025403 P2RX4 P2RX4 PSMD9 PSMD9 SLC4A8 SLC4A8 FRMD4A FRMD4A BLK BLK C1QTNF12 C1QTNF12 NTSR1 NTSR1 RBP4 RBP4 ABAT ABAT ATP13A2 ATP13A2 DRD2 DRD2 EDN3 EDN3 TCF7L2 TCF7L2 CHMP2A CHMP2A TACR1 TACR1 SDC4 SDC4 BAIAP3 BAIAP3 GHRL GHRL ENSTSYP00000028129 ENSTSYP00000028129 KCNN4 KCNN4 ADCYAP1 ADCYAP1 ABCG1 ABCG1 PLA2G4A PLA2G4A ENSTSYP00000028600 ENSTSYP00000028600 SDC1 SDC1 SRI SRI ACHE ACHE ILDR1 ILDR1 ENSTSYP00000028976 ENSTSYP00000028976 ENSTSYP00000029007 ENSTSYP00000029007 NNAT NNAT TMED10 TMED10 MYH10 MYH10 TRPM4 TRPM4 GIPR GIPR IGF1 IGF1 CLASP1 CLASP1 LOC103269764 LOC103269764 TGFB3 TGFB3 SDCBP SDCBP ADAM8 ADAM8 SCAMP5 SCAMP5 TGFB1 TGFB1 MYO18A MYO18A HGS HGS SYT4 SYT4 LOC103256667 LOC103256667 IL4R IL4R RAB3GAP1-2 RAB3GAP1-2 SYT1 SYT1 TGFB2 TGFB2 S100A10 S100A10 RAB3GAP1 RAB3GAP1 SELENOT SELENOT ADORA2A ADORA2A VSNL1 VSNL1 CACNB4 CACNB4 C1QTNF1 C1QTNF1 EZR EZR GABBR1 GABBR1 PPP3CB PPP3CB CACNA1G CACNA1G NLGN2 NLGN2 GPR68 GPR68 ENSTSYP00000024397 ENSTSYP00000024397 PLA2G1B PLA2G1B UNC13D UNC13D PCSK1 PCSK1 APBB1 APBB1 ENSTSYP00000033676 ENSTSYP00000033676 STX1A STX1A AVPR1A AVPR1A APBB3 APBB3 BMP2 BMP2 MAP2K6 MAP2K6 PPARD PPARD LOC103252420 LOC103252420 BSG BSG SYT7 SYT7 NR0B2 NR0B2 LRRC8A LRRC8A TSG101 TSG101 ENSTSYP00000021856 ENSTSYP00000021856 RASL10B RASL10B GRK2 GRK2 NR1H2 NR1H2 CHRNB2 CHRNB2 SPP1 SPP1 CACNA1I CACNA1I ARHGEF7 ARHGEF7 SNF8 SNF8 PINK1 PINK1 CAPN10 CAPN10 CLASP2 CLASP2 EXOC1 EXOC1 ANO1 ANO1 DNM1L DNM1L DOC2B DOC2B INHA INHA IER3IP1 IER3IP1 CACNB2 CACNB2 PARD6A PARD6A VPS4A VPS4A SYTL4 SYTL4 CD2AP CD2AP PDCD6IP PDCD6IP RPH3AL RPH3AL SLC12A2 SLC12A2 CADPS CADPS SLC30A8 SLC30A8 ADAM9 ADAM9 C2CD2L C2CD2L AIMP1 AIMP1 EXPH5 EXPH5 TM7SF3 TM7SF3 FGA FGA HFE HFE FGG FGG CPB2 CPB2 C1QTNF3 C1QTNF3 PTPN23 PTPN23 TFR2 TFR2 TNFRSF11A TNFRSF11A TREM2 TREM2 AVP AVP HIF1A HIF1A C1QTNF6 C1QTNF6 FGR FGR TRH TRH INHBA INHBA NR1H4 NR1H4 SMPD3 SMPD3 STX1B STX1B CDK5 CDK5 MIF MIF TTN TTN VDR VDR ENSTSYP00000017365 ENSTSYP00000017365 SPHK2 SPHK2 RAB2B RAB2B ENSTSYP00000017425 ENSTSYP00000017425 LOC103274738 LOC103274738 SYK SYK ITGB2 ITGB2 HYAL3 HYAL3 GHRH GHRH CACNA1H CACNA1H DTNBP1 DTNBP1 ARF6 ARF6 NLGN1 NLGN1 ENSTSYP00000018519 ENSTSYP00000018519 GRP GRP GCK GCK MCU MCU CREB1 CREB1 KIAA0100 KIAA0100 NMB NMB STX4 STX4 ADORA2B ADORA2B GCG GCG SPINK1 SPINK1 MYOM1 MYOM1 VPS35 VPS35 GIP GIP STXBP5 STXBP5 CD160 CD160 GALR1 GALR1 GOLPH3 GOLPH3 RAB15 RAB15 ENSTSYP00000003488 ENSTSYP00000003488 DAB2 DAB2 GATA1 GATA1 FGB FGB BMP6 BMP6 VIP VIP SYT10 SYT10 MYRIP MYRIP GHRHR GHRHR STAM STAM CASR CASR PTPN11 PTPN11 CADPS2 CADPS2 RAB3D RAB3D P2RY1 P2RY1 ISL1 ISL1 PLA2G6 PLA2G6 TRPM2 TRPM2 SEC24A SEC24A WLS WLS SNX4 SNX4 ANKRD1 ANKRD1 CFTR CFTR RAB27A RAB27A AVPR1B AVPR1B PLA2G3 PLA2G3 VEGFC VEGFC KMO KMO ECRG4 ECRG4 PPID PPID P2RX7 P2RX7 ENSTSYP00000001924 ENSTSYP00000001924 RAB7A RAB7A HMMR HMMR LOC103265753 LOC103265753 CYP19A1 CYP19A1 ENSTSYP00000007785 ENSTSYP00000007785 CD177 CD177 SYT9 SYT9 PCK2 PCK2 GOLPH3L GOLPH3L LAMP1 LAMP1 SMAD4 SMAD4 OSBP OSBP GPLD1 GPLD1 VAMP8 VAMP8 RAB27B RAB27B MPC2 MPC2 CARTPT CARTPT TMF1 TMF1 ACSL4 ACSL4 EDN1 EDN1 ITGAM ITGAM ADCY8 ADCY8 KCNB1 KCNB1 ENSTSYP00000011178 ENSTSYP00000011178 TACR2 TACR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (250 aa)
ENSTSYP00000025403annotation not available (567 aa)
P2RX4P2X purinoceptor 4 isoform X2. (388 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (220 aa)
SLC4A8Anion exchange protein. (1094 aa)
FRMD4AFERM domain-containing protein 4A. (534 aa)
BLKTyrosine-protein kinase. (388 aa)
C1QTNF12Adipolin. (300 aa)
NTSR1Neurotensin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (414 aa)
RBP4Retinol-binding protein 4. (155 aa)
ABAT4-aminobutyrate aminotransferase, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (512 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1149 aa)
DRD2D(2) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (443 aa)
EDN3Endothelin-3 isoform X1. (214 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (565 aa)
CHMP2ACharged multivesicular body protein 2a. (222 aa)
TACR1substance-P receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
BAIAP3BAI1-associated protein 3. (1034 aa)
GHRLAppetite-regulating hormone. (117 aa)
ENSTSYP00000028129annotation not available (195 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (260 aa)
ADCYAP1LOW QUALITY PROTEIN: pituitary adenylate cyclase-activating polypeptide. (176 aa)
ABCG1ATP-binding cassette sub-family G member 1 isoform X1. (678 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSTSYP00000028600annotation not available (251 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (394 aa)
SRISorcin. (198 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (525 aa)
ILDR1Immunoglobulin-like domain-containing receptor 1 isoform X1. (543 aa)
ENSTSYP00000028976annotation not available (213 aa)
ENSTSYP00000029007annotation not available (89 aa)
NNATNeuronatin isoform X2. (81 aa)
TMED10Transmembrane emp24 domain-containing protein 10 isoform X1. (219 aa)
MYH10Myosin-10 isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (978 aa)
GIPRGastric inhibitory polypeptide receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (443 aa)
IGF1Insulin-like growth factor I isoform X1. (209 aa)
CLASP1CLIP-associating protein 1. (1539 aa)
LOC103269764Stromal cell-derived factor 1-like; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SDCBPSyntenin-1 isoform X2. (302 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8. (801 aa)
SCAMP5Secretory carrier-associated membrane protein. (237 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
MYO18AUnconventional myosin-XVIIIa isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2058 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
SYT4Synaptotagmin-4 isoform X1. (425 aa)
LOC103256667Hepatocyte nuclear factor 1-alpha isoform X2. (227 aa)
IL4RInterleukin-4 receptor subunit alpha. (812 aa)
RAB3GAP1-2Rab3 GTPase-activating protein catalytic subunit. (58 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
S100A10Protein S100-A10; Belongs to the S-100 family. (97 aa)
RAB3GAP1Rab3 GTPase-activating protein catalytic subunit isoform X1. (577 aa)
SELENOTSelenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (199 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
VSNL1Visinin-like protein 1. (191 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (514 aa)
C1QTNF1Complement C1q tumor necrosis factor-related protein 1. (280 aa)
EZREzrin isoform X3. (598 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1 isoform X1. (960 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2311 aa)
NLGN2Neuroligin-2. (760 aa)
GPR68Ovarian cancer G-protein coupled receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
ENSTSYP00000024397annotation not available (102 aa)
PLA2G1BPhospholipase A(2). (147 aa)
UNC13DProtein unc-13 homolog D. (1115 aa)
PCSK1Neuroendocrine convertase 1 isoform X1; Belongs to the peptidase S8 family. (753 aa)
APBB1Amyloid beta A4 precursor protein-binding family B member 1 isoform X4. (490 aa)
ENSTSYP00000033676annotation not available (300 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (252 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (418 aa)
APBB3Amyloid beta A4 precursor protein-binding family B member 3 isoform X1. (493 aa)
BMP2Bone morphogenetic protein 2. (398 aa)
MAP2K6LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (352 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
LOC103252420Endothelial transcription factor GATA-2. (93 aa)
BSGLOW QUALITY PROTEIN: basigin. (234 aa)
SYT7Synaptotagmin 7. (659 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (253 aa)
LRRC8AVolume-regulated anion channel subunit LRRC8A. (810 aa)
TSG101Tumor susceptibility gene 101 protein isoform X2. (393 aa)
ENSTSYP00000021856annotation not available (88 aa)
RASL10BRas-like protein family member 10B. (203 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (621 aa)
NR1H2Oxysterols receptor LXR-beta. (449 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (481 aa)
SPP1Osteopontin isoform X1. (314 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1952 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7 isoform X1. (705 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (510 aa)
CAPN10Calpain-10 isoform X1; Belongs to the peptidase C2 family. (674 aa)
CLASP2CLIP-associating protein 2 isoform X2. (1495 aa)
EXOC1Exocyst complex component 1 isoform X1. (901 aa)
ANO1Anoctamin. (937 aa)
DNM1LDynamin-1-like protein. (749 aa)
DOC2BDouble C2-like domain-containing protein beta. (346 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (367 aa)
IER3IP1Immediate early response 3-interacting protein 1. (82 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (612 aa)
PARD6APartitioning defective 6 homolog alpha. (346 aa)
VPS4AVacuolar protein sorting-associated protein 4A isoform X2; Belongs to the AAA ATPase family. (437 aa)
SYTL4Synaptotagmin-like protein 4. (671 aa)
CD2APCD2-associated protein. (638 aa)
PDCD6IPProgrammed cell death 6-interacting protein isoform X3. (869 aa)
RPH3ALRab effector Noc2. (306 aa)
SLC12A2Solute carrier family 12 member 2. (500 aa)
CADPSCalcium-dependent secretion activator 1 isoform X1. (770 aa)
SLC30A8Zinc transporter 8. (362 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9. (795 aa)
C2CD2LPhospholipid transfer protein C2CD2L isoform X1. (707 aa)
AIMP1Aminoacyl tRNA synthase complex-interacting multifunctional protein 1. (312 aa)
EXPH5Exophilin-5. (1971 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
FGAFibrinogen alpha chain. (872 aa)
HFELOW QUALITY PROTEIN: hereditary hemochromatosis protein; Belongs to the MHC class I family. (345 aa)
FGGFibrinogen gamma chain isoform X1. (461 aa)
CPB2Carboxypeptidase B2. (261 aa)
C1QTNF3Complement C1q tumor necrosis factor-related protein 3 isoform X1. (319 aa)
PTPN23Tyrosine-protein phosphatase non-receptor type 23 isoform X1. (1636 aa)
TFR2Transferrin receptor protein 2. (669 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (238 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
AVPVasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (107 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (842 aa)
C1QTNF6Complement C1q tumor necrosis factor-related protein 6. (266 aa)
FGRTyrosine-protein kinase. (526 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (215 aa)
INHBAInhibin beta A chain. (426 aa)
NR1H4Bile acid receptor isoform X1. (486 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
STX1Bsyntaxin-1B; Belongs to the syntaxin family. (243 aa)
CDK5Cyclin-dependent-like kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
TTNTitin isoform X2. (5602 aa)
VDRVitamin D3 receptor. (408 aa)
ENSTSYP00000017365annotation not available (56 aa)
SPHK2Sphingosine kinase 2 isoform X1. (654 aa)
RAB2BRas-related protein Rab-2B isoform X1. (216 aa)
ENSTSYP00000017425annotation not available (69 aa)
LOC103274738Myeloid cell surface antigen CD33-like isoform X1. (302 aa)
SYKTyrosine-protein kinase. (634 aa)
ITGB2Integrin beta. (769 aa)
HYAL3Hyaluronidase. (424 aa)
GHRHSomatoliberin. (107 aa)
CACNA1HVoltage-dependent T-type calcium channel subunit alpha-1H. (2290 aa)
DTNBP1Dysbindin. (343 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
NLGN1Neuroligin-1. (616 aa)
ENSTSYP00000018519annotation not available (145 aa)
GRPGastrin-releasing peptide. (148 aa)
GCKPhosphotransferase. (467 aa)
MCUCalcium uniporter protein, mitochondrial. (350 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
KIAA0100Protein KIAA0100 homolog isoform X1. (2235 aa)
NMBneuromedin-B isoform X2. (121 aa)
STX4Syntaxin-4 isoform X4; Belongs to the syntaxin family. (298 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
GCGGlucagon. (180 aa)
SPINK1Serine protease inhibitor Kazal-type 1. (79 aa)
MYOM1Myomesin-1. (1655 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
GIPGastric inhibitory polypeptide. (150 aa)
STXBP5Syntaxin-binding protein 5 isoform X1. (1150 aa)
CD160CD160 antigen isoform X2. (181 aa)
GALR1Galanin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
GOLPH3Golgi phosphoprotein 3. (231 aa)
RAB15Ras-related protein Rab-15 isoform X3. (170 aa)
ENSTSYP00000003488annotation not available (97 aa)
DAB2Disabled homolog 2. (769 aa)
GATA1Erythroid transcription factor. (413 aa)
FGBFibrinogen beta chain isoform X1. (492 aa)
BMP6Bone morphogenetic protein 6. (513 aa)
VIPVIP peptides isoform X1. (170 aa)
SYT10Synaptotagmin-10. (523 aa)
MYRIPRab effector MyRIP. (588 aa)
GHRHRGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
STAMSignal transducing adapter molecule 1 isoform X1. (538 aa)
CASRLOW QUALITY PROTEIN: extracellular calcium-sensing receptor. (1015 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
CADPS2Calcium-dependent secretion activator 2 isoform X5. (1296 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
P2RY1P2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
ISL1Insulin gene enhancer protein ISL-1 isoform X1. (353 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2 isoform X1. (807 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2 isoform X1. (1573 aa)
SEC24AProtein transport protein Sec24A isoform X1. (1093 aa)
WLSProtein wntless homolog isoform X2. (543 aa)
SNX4Sorting nexin-4 isoform X2. (450 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (319 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
RAB27ARas-related protein Rab-27A. (221 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (425 aa)
PLA2G3Group 3 secretory phospholipase A2. (506 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (407 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (487 aa)
ECRG4Augurin. (140 aa)
PPIDPeptidyl-prolyl cis-trans isomerase D. (370 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
ENSTSYP00000001924annotation not available (127 aa)
RAB7ARas-related protein Rab-7a isoform X1. (214 aa)
HMMRHyaluronan mediated motility receptor. (685 aa)
LOC103265753DNA-binding protein RFX6-like. (479 aa)
CYP19A1Aromatase; Belongs to the cytochrome P450 family. (503 aa)
ENSTSYP00000007785annotation not available (217 aa)
CD177CD177 antigen. (428 aa)
SYT9Synaptotagmin-9. (491 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X1. (640 aa)
GOLPH3LGolgi phosphoprotein 3-like isoform X1. (286 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (411 aa)
SMAD4Mothers against decapentaplegic homolog. (551 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (807 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D. (840 aa)
VAMP8Vesicle-associated membrane protein 8. (100 aa)
RAB27BRas-related protein Rab-27B. (218 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
CARTPTCART prepropeptide. (116 aa)
TMF1TATA element modulatory factor isoform X1. (1093 aa)
ACSL4long-chain-fatty-acid--CoA ligase 4 isoform X1. (711 aa)
EDN1Endothelin-1. (202 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
ADCY8Adenylate cyclase type 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (931 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
ENSTSYP00000011178annotation not available (227 aa)
TACR2Tachykinin receptor 2. (337 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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