34 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	ABCA12	ATP-binding cassette sub-family A member 12. (2595 aa)
	COMMD1	COMM domain-containing protein 1 isoform X1. (189 aa)
	LRIG2	Leucine-rich repeats and immunoglobulin-like domains protein 2. (1065 aa)
	GBF1	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1. (1860 aa)
	STX4	Syntaxin-4 isoform X4; Belongs to the syntaxin family. (298 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1280 aa)
	ENSTSYP00000023666	annotation not available (397 aa)
	CD247	CD247 molecule. (145 aa)
	COMMD1-2	COMM domain-containing protein 1 isoform X2. (180 aa)
	DMWD	Dystrophia myotonica WD repeat-containing protein. (624 aa)
	GPM6B	Neuronal membrane glycoprotein M6-b isoform X1. (328 aa)
	RANGRF	Ran guanine nucleotide release factor isoform X1. (186 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	CTNNB1	Catenin beta-1 isoform X1. (783 aa)
	WDR20	WD repeat-containing protein 20 isoform X2. (612 aa)
	HFE	LOW QUALITY PROTEIN: hereditary hemochromatosis protein; Belongs to the MHC class I family. (345 aa)
	MAP1A	Microtubule-associated protein 1A isoform X1. (3042 aa)
	TM9SF4	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (652 aa)
	RAB11FIP5	Rab11 family-interacting protein 5. (1289 aa)
	TAX1BP3	Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
	TOR1A	torsin-1A. (332 aa)
	ARF6	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	TMEM35A	Transmembrane protein 35A. (167 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	LOC103276602	Golgi-associated PDZ and coiled-coil motif-containing protein. (462 aa)
	AKT1	Non-specific serine/threonine protein kinase. (393 aa)
	LOC103261725	LOW QUALITY PROTEIN: Golgi-associated PDZ and coiled-coil motif-containing protein-like. (425 aa)
	KCNAB2	Voltage-gated potassium channel subunit beta-2 isoform X2. (415 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
	ACTN2	Alpha-actinin-2. (894 aa)
	PICALM	Phosphatidylinositol-binding clathrin assembly protein isoform X11. (652 aa)
	STX3	Syntaxin-3 isoform X3; Belongs to the syntaxin family. (294 aa)
	RIC3	Protein RIC-3. (127 aa)
	SNX33	Sorting nexin. (574 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	CAV3	ENSTSYP00000026567	ENSTSYP00000033760	Alpha-actinin-2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.513
AKT1	ARF6	ENSTSYP00000030955	ENSTSYP00000018330	Non-specific serine/threonine protein kinase.	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.618
AKT1	CAV3	ENSTSYP00000030955	ENSTSYP00000033760	Non-specific serine/threonine protein kinase.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.505
AKT1	CD247	ENSTSYP00000030955	ENSTSYP00000022234	Non-specific serine/threonine protein kinase.	CD247 molecule.	0.522
AKT1	CTNNB1	ENSTSYP00000030955	ENSTSYP00000010210	Non-specific serine/threonine protein kinase.	Catenin beta-1 isoform X1.	0.888
AKT1	EGF	ENSTSYP00000030955	ENSTSYP00000008584	Non-specific serine/threonine protein kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.628
AKT1	ERBB4	ENSTSYP00000030955	ENSTSYP00000006840	Non-specific serine/threonine protein kinase.	Receptor protein-tyrosine kinase.	0.569
AKT1	MAP1A	ENSTSYP00000030955	ENSTSYP00000014402	Non-specific serine/threonine protein kinase.	Microtubule-associated protein 1A isoform X1.	0.404
AKT1	TNF	ENSTSYP00000030955	ENSTSYP00000027201	Non-specific serine/threonine protein kinase.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.710
ARF6	AKT1	ENSTSYP00000018330	ENSTSYP00000030955	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Non-specific serine/threonine protein kinase.	0.618
ARF6	CAV3	ENSTSYP00000018330	ENSTSYP00000033760	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.488
ARF6	ERBB4	ENSTSYP00000018330	ENSTSYP00000006840	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Receptor protein-tyrosine kinase.	0.515
ARF6	GBF1	ENSTSYP00000018330	ENSTSYP00000005796	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1.	0.804
ARF6	PICALM	ENSTSYP00000018330	ENSTSYP00000026479	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Phosphatidylinositol-binding clathrin assembly protein isoform X11.	0.459
CAV3	ACTN2	ENSTSYP00000033760	ENSTSYP00000026567	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Alpha-actinin-2.	0.513
CAV3	AKT1	ENSTSYP00000033760	ENSTSYP00000030955	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Non-specific serine/threonine protein kinase.	0.505
CAV3	ARF6	ENSTSYP00000033760	ENSTSYP00000018330	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.488
CAV3	CTNNB1	ENSTSYP00000033760	ENSTSYP00000010210	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Catenin beta-1 isoform X1.	0.599
CAV3	EGF	ENSTSYP00000033760	ENSTSYP00000008584	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.531
CAV3	ERBB4	ENSTSYP00000033760	ENSTSYP00000006840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Receptor protein-tyrosine kinase.	0.808