STRINGSTRING
THBS4 THBS4 COL4A2 COL4A2 MMRN1 MMRN1 LAMC3 LAMC3 COCH COCH SMOC1 SMOC1 LAMA2 LAMA2 TNN TNN COL11A1 COL11A1 LAMA1 LAMA1 MMP2 MMP2 IL13 IL13 IFNG IFNG MMP9 MMP9 MORC3 MORC3 COL2A1 COL2A1 LOC103255181 LOC103255181 COL6A3 COL6A3 COL4A4 COL4A4 THBS1 THBS1 EGFLAM EGFLAM COL8A1 COL8A1 LOC103271638 LOC103271638 TRIM33 TRIM33 VCAN VCAN LOC103259286 LOC103259286 ECM2 ECM2 EMILIN2 EMILIN2 IMPG1 IMPG1 FREM1 FREM1 CUNH11orf53 CUNH11orf53 COL14A1 COL14A1 NID2 NID2 SSC4D SSC4D COL7A1 COL7A1 COL15A1 COL15A1 NID1 NID1 LOXL2 LOXL2 AGT AGT SERPINE2 SERPINE2 LOC103251060 LOC103251060 FRAS1 FRAS1 MMP8 MMP8 WNT2 WNT2 ADAMTS6 ADAMTS6 IL1B IL1B CASK CASK RELL2 RELL2 COL1A2 COL1A2 FN1 FN1 MATN1 MATN1 MEGF9 MEGF9 COL28A1 COL28A1 MATN3 MATN3 LAMB2 LAMB2 P3H2 P3H2 TINAG TINAG COL12A1 COL12A1 PXDN PXDN LAMC2 LAMC2 COL4A6 COL4A6 COL4A5 COL4A5 LAMB1 LAMB1 NTN1 NTN1 OTOL1 OTOL1 ANGPT1 ANGPT1 TGFBI TGFBI IL17A IL17A MATN4 MATN4 ZPLD1 ZPLD1 PCSK6 PCSK6 HMCN1 HMCN1 ENSTSYP00000011461 ENSTSYP00000011461 COL6A5 COL6A5 COL3A1 COL3A1 LAMB4 LAMB4 USHBP1 USHBP1 TGM4 TGM4 COL4A1 COL4A1 IMPG2 IMPG2 LTBP1 LTBP1 ZP2 ZP2 VTN VTN LAMA4 LAMA4 NTNG1 NTNG1 EGFL8 EGFL8 COL5A2 COL5A2 LGALS3BP LGALS3BP COL18A1 COL18A1 SHH SHH LOXL1 LOXL1 LUM LUM PVALB PVALB NAV2 NAV2 COL5A3 COL5A3 CUNH6orf15 CUNH6orf15 COL8A2 COL8A2 ENSTSYP00000017967 ENSTSYP00000017967 COL6A2 COL6A2 NTNG2 NTNG2 MS4A12 MS4A12 IL7 IL7 PODNL1 PODNL1 PTPRZ1 PTPRZ1 LOC103262178 LOC103262178 NTN4 NTN4 COL1A1 COL1A1 LOC103270873 LOC103270873 NCAM1 NCAM1 LAMA5 LAMA5 CILP CILP ADAMTS10 ADAMTS10 DCN DCN LAMA3 LAMA3 AMELX AMELX ECM1 ECM1 TIMP3 TIMP3 LAMC1 LAMC1 VIT VIT LOC103261307 LOC103261307 COLQ COLQ HSPG2 HSPG2 BGN BGN ENSTSYP00000024163 ENSTSYP00000024163 LOC103255362 LOC103255362 COL5A1 COL5A1 LTBP4 LTBP4 BCAN BCAN DSPP DSPP MMRN2 MMRN2 ADAMTS4 ADAMTS4 PAQR4 PAQR4 TNF TNF LOC103260670 LOC103260670 ENSTSYP00000027785 ENSTSYP00000027785 RBP3 RBP3 ICAM1 ICAM1 LOC103277266 LOC103277266 LOC103262398 LOC103262398 TIMP2 TIMP2 AGRN AGRN EGFL7 EGFL7 ACHE ACHE COL10A1 COL10A1 SERPINE1 SERPINE1 COL11A2 COL11A2 LOC103269101 LOC103269101 TNC TNC LOC103250817 LOC103250817 MFAP4 MFAP4 SPARC SPARC LOC103269764 LOC103269764 TGFB3 TGFB3 PMP22 PMP22 LAMB3 LAMB3 TNR TNR CCDC80 CCDC80 TGFB2 TGFB2 FBN2 FBN2 MATN2 MATN2 ABI3BP ABI3BP APLP1 APLP1 LOX LOX PAPLN PAPLN POSTN POSTN NDP NDP COL16A1 COL16A1 FBLN5 FBLN5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THBS4Thrombospondin-4. (865 aa)
COL4A2Collagen alpha-2(IV) chain. (1702 aa)
MMRN1Multimerin-1. (1219 aa)
LAMC3Laminin subunit gamma-3. (1431 aa)
COCHCochlin isoform X1. (550 aa)
SMOC1SPARC-related modular calcium-binding protein 1. (401 aa)
LAMA2Laminin subunit alpha-2. (2586 aa)
TNNtenascin-N isoform X1. (1297 aa)
COL11A1Collagen alpha-1(XI) chain. (1446 aa)
LAMA1Laminin subunit alpha-1. (3075 aa)
MMP272 kDa type IV collagenase. (662 aa)
IL13Interleukin-13. (139 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
MMP9Matrix metalloproteinase-9. (710 aa)
MORC3MORC family CW-type zinc finger protein 3 isoform X1. (940 aa)
COL2A1Collagen alpha-1(II) chain. (1487 aa)
LOC103255181Usherin. (3659 aa)
COL6A3Collagen alpha-3(VI) chain. (3159 aa)
COL4A4Collagen alpha-4(IV) chain. (1691 aa)
THBS1Thrombospondin-1. (1178 aa)
EGFLAMPikachurin isoform X2. (1017 aa)
COL8A1Collagen alpha-1(VIII) chain. (745 aa)
LOC103271638Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (272 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33. (1127 aa)
VCANVersican core protein isoform X3. (1634 aa)
LOC103259286Collagen alpha-3(IV) chain-like. (884 aa)
ECM2Extracellular matrix protein 2 isoform X1. (694 aa)
EMILIN2EMILIN-2. (1060 aa)
IMPG1LOW QUALITY PROTEIN: interphotoreceptor matrix proteoglycan 1. (753 aa)
FREM1FRAS1-related extracellular matrix protein 1. (2177 aa)
CUNH11orf53Uncharacterized protein C11orf53 homolog. (285 aa)
COL14A1Collagen alpha-1(XIV) chain. (1692 aa)
NID2Nidogen-2. (1354 aa)
SSC4DScavenger receptor cysteine-rich domain-containing group B protein. (541 aa)
COL7A1Collagen alpha-1(VII) chain. (2943 aa)
COL15A1Collagen alpha-1(XV) chain. (1328 aa)
NID1Nidogen-1. (1248 aa)
LOXL2Lysyl oxidase homolog 2 isoform X1. (774 aa)
AGTAngiotensinogen; Belongs to the serpin family. (487 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (408 aa)
LOC103251060Protein eyes shut homolog. (297 aa)
FRAS1Extracellular matrix protein FRAS1. (3336 aa)
MMP8Neutrophil collagenase. (466 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
ADAMTS6A disintegrin and metalloproteinase with thrombospondin motifs 6. (644 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (267 aa)
CASKPeripheral plasma membrane protein CASK; Belongs to the MAGUK family. (833 aa)
RELL2RELT-like protein 2 isoform X1. (303 aa)
COL1A2Collagen alpha-2(I) chain isoform X2. (1366 aa)
FN1Fibronectin isoform X2. (2450 aa)
MATN1Cartilage matrix protein. (447 aa)
MEGF9Multiple epidermal growth factor-like domains protein 9. (538 aa)
COL28A1Collagen alpha-1(XXVIII) chain. (1126 aa)
MATN3Matrilin-3. (454 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
P3H2Prolyl 3-hydroxylase 2. (595 aa)
TINAGTubulointerstitial nephritis antigen; Belongs to the peptidase C1 family. (476 aa)
COL12A1Collagen alpha-1(XII) chain. (3007 aa)
PXDNPeroxidasin homolog. (1479 aa)
LAMC2Laminin subunit gamma-2. (1191 aa)
COL4A6Collagen alpha-6(IV) chain isoform X1. (1706 aa)
COL4A5Collagen alpha-5(IV) chain. (622 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
NTN1Netrin-1. (597 aa)
OTOL1Otolin-1. (474 aa)
ANGPT1Angiopoietin-1 isoform X1. (498 aa)
TGFBITransforming growth factor-beta-induced protein ig-h3 isoform X1. (670 aa)
IL17Ainterleukin-17A. (152 aa)
MATN4Matrilin-4 isoform X1. (624 aa)
ZPLD1Zona pellucida-like domain-containing protein 1 isoform X2. (425 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (969 aa)
HMCN1Hemicentin-1. (5635 aa)
ENSTSYP00000011461annotation not available (367 aa)
COL6A5Collagen alpha-5(VI) chain. (2556 aa)
COL3A1Collagen alpha-1(III) chain. (1466 aa)
LAMB4Laminin subunit beta-4. (1759 aa)
USHBP1Usher syndrome type-1C protein-binding protein 1. (694 aa)
TGM4Protein-glutamine gamma-glutamyltransferase 4. (684 aa)
COL4A1Collagen alpha-1(IV) chain. (1621 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1202 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1. (1011 aa)
ZP2Zona pellucida sperm-binding protein 2. (745 aa)
VTNVitronectin. (474 aa)
LAMA4Laminin subunit alpha-4. (1777 aa)
NTNG1netrin-G1. (403 aa)
EGFL8LOW QUALITY PROTEIN: uncharacterized protein LOC103271308. (279 aa)
COL5A2Collagen alpha-2(V) chain isoform X1. (1499 aa)
LGALS3BPGalectin-3-binding protein. (587 aa)
COL18A1Collagen alpha-1(XVIII) chain isoform X2. (1512 aa)
SHHSonic hedgehog signaling molecule. (368 aa)
LOXL1Lysyl oxidase homolog 1. (409 aa)
LUMLumican. (338 aa)
PVALBParvalbumin alpha; Belongs to the parvalbumin family. (78 aa)
NAV2Neuron navigator 2. (2392 aa)
COL5A3LOW QUALITY PROTEIN: collagen alpha-3(V) chain. (1676 aa)
CUNH6orf15Uncharacterized protein C6orf15 homolog. (312 aa)
COL8A2Collagen alpha-2(VIII) chain isoform X1. (700 aa)
ENSTSYP00000017967annotation not available (148 aa)
COL6A2Collagen alpha-2(VI) chain isoform X1. (1019 aa)
NTNG2Netrin G2. (384 aa)
MS4A12Membrane-spanning 4-domains subfamily A member 12. (262 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
PODNL1Podocan-like protein 1. (499 aa)
PTPRZ1Receptor-type tyrosine-protein phosphatase zeta isoform X1. (2301 aa)
LOC103262178Collagen alpha-5(IV) chain-like. (461 aa)
NTN4Netrin-4. (608 aa)
COL1A1Collagen alpha-1(I) chain. (1462 aa)
LOC103270873Usherin-like. (1546 aa)
NCAM1Neural cell adhesion molecule 1 isoform X10. (869 aa)
LAMA5Laminin subunit alpha-5. (3488 aa)
CILPCartilage intermediate layer protein 1. (1184 aa)
ADAMTS10A disintegrin and metalloproteinase with thrombospondin motifs 10. (534 aa)
DCNDecorin; May affect the rate of fibrils formation. (361 aa)
LAMA3Laminin subunit alpha-3. (892 aa)
AMELXAmelogenin, X isoform. (205 aa)
ECM1Extracellular matrix protein 1 isoform X2. (544 aa)
TIMP3Metalloproteinase inhibitor 3. (170 aa)
LAMC1Laminin subunit gamma-1. (1593 aa)
VITVitrin isoform X1. (678 aa)
LOC103261307Laminin subunit alpha-3. (482 aa)
COLQAcetylcholinesterase collagenic tail peptide. (434 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein. (4355 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (370 aa)
ENSTSYP00000024163annotation not available (1023 aa)
LOC103255362Sialin. (124 aa)
COL5A1Collagen alpha-1(V) chain. (1844 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4. (1507 aa)
BCANBrevican core protein. (903 aa)
DSPPDentin sialophosphoprotein. (990 aa)
MMRN2Multimerin-2. (941 aa)
ADAMTS4A disintegrin and metalloproteinase with thrombospondin motifs 4 isoform X2. (837 aa)
PAQR4Progestin and adipoQ receptor family member 4. (206 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
LOC103260670A disintegrin and metalloproteinase with thrombospondin motifs 6-like. (310 aa)
ENSTSYP00000027785annotation not available (171 aa)
RBP3Retinol-binding protein 3. (1168 aa)
ICAM1Intercellular adhesion molecule 1. (281 aa)
LOC103277266LOW QUALITY PROTEIN: neurocan core protein-like. (1021 aa)
LOC103262398Complement C1q and tumor necrosis factor-related protein 9A. (333 aa)
TIMP2Metalloproteinase inhibitor 2. (201 aa)
AGRNLOW QUALITY PROTEIN: agrin. (1908 aa)
EGFL7Epidermal growth factor-like protein 7. (268 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (525 aa)
COL10A1Collagen alpha-1(X) chain. (673 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
COL11A2Collagen alpha-2(XI) chain isoform X1. (1736 aa)
LOC103269101Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (301 aa)
TNCTenascin isoform X1. (2201 aa)
LOC103250817Cartilage oligomeric matrix protein. (202 aa)
MFAP4Microfibril-associated glycoprotein 4. (272 aa)
SPARCSPARC isoform X3. (303 aa)
LOC103269764Stromal cell-derived factor 1-like; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
LAMB3Laminin subunit beta-3. (1170 aa)
TNRLOW QUALITY PROTEIN: tenascin-R. (1359 aa)
CCDC80Coiled-coil domain-containing protein 80 isoform X1. (950 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
FBN2Fibrillin-2. (2912 aa)
MATN2Matrilin-2 isoform X1. (956 aa)
ABI3BPTarget of Nesh-SH3. (1747 aa)
APLP1Amyloid-like protein 1. (636 aa)
LOXProtein-lysine 6-oxidase. (203 aa)
PAPLNPapilin. (1174 aa)
POSTNPeriostin isoform X1. (836 aa)
NDPNorrin. (133 aa)
COL16A1Collagen alpha-1(XVI) chain. (1610 aa)
FBLN5Fibulin-5. (490 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.