STRINGSTRING
TMEFF2 TMEFF2 LRP6 LRP6 VWCE VWCE MUC13 MUC13 SNED1 SNED1 PLAU PLAU LAMB2 LAMB2 MATN3 MATN3 FAT4 FAT4 ASTN1 ASTN1 MEGF9 MEGF9 ADGRL4 ADGRL4 MATN1 MATN1 EFEMP1 EFEMP1 MEP1B MEP1B PGAP6 PGAP6 ATRN ATRN LOC103274258 LOC103274258 CD93 CD93 FRAS1 FRAS1 ADAM19 ADAM19 TENM3 TENM3 SELL SELL LOC103260743 LOC103260743 TMEM8B TMEM8B HHIP HHIP DLL1 DLL1 LOC103251060 LOC103251060 ITGB8 ITGB8 MASP2 MASP2 CELSR1 CELSR1 EREG EREG NRG4 NRG4 MEGF10 MEGF10 NID1 NID1 CCBE1 CCBE1 NID2 NID2 ITGBL1 ITGBL1 IMPG1 IMPG1 TENM4 TENM4 LOC103256219 LOC103256219 PEAR1 PEAR1 VCAN VCAN SCUBE1 SCUBE1 JAG1 JAG1 VWA2 VWA2 LOC103271083 LOC103271083 EGFLAM EGFLAM PLAT PLAT VWDE VWDE THBS1 THBS1 EGFL6 EGFL6 CNTNAP1 CNTNAP1 CUBN CUBN SCUBE3 SCUBE3 SCARF2 SCARF2 BTC BTC LAMA1 LAMA1 HABP2 HABP2 TNN TNN LAMA2 LAMA2 ADAM12 ADAM12 FAT1 FAT1 LRP1B LRP1B LAMC3 LAMC3 SELP SELP SVEP1 SVEP1 MMRN1 MMRN1 THBS4 THBS4 LAMC2 LAMC2 TLL1 TLL1 MEP1A MEP1A EGF EGF LOC103268533 LOC103268533 FBLN5 FBLN5 NOTCH4 NOTCH4 UMOD UMOD NRG2 NRG2 LOC103250642 LOC103250642 CNTNAP4 CNTNAP4 NOTCH1 NOTCH1 ACAN ACAN CD248 CD248 JAG2 JAG2 LOC103251212 LOC103251212 MATN2 MATN2 FBN2 FBN2 PROZ PROZ EPGN EPGN TNR TNR ADAM8 ADAM8 LAMB3 LAMB3 SCARF1 SCARF1 HMCN2 HMCN2 LOC103275819 LOC103275819 OIT3 OIT3 TNC TNC EGFL7 EGFL7 AGRN AGRN THBS3 THBS3 LDLR LDLR LOC103277266 LOC103277266 MSANTD3-TMEFF1 MSANTD3-TMEFF1 NRG1 NRG1 MASP1 MASP1 WIF1 WIF1 MEGF8 MEGF8 MALRD1 MALRD1 LRP5 LRP5 NAGPA NAGPA ADAM15 ADAM15 LOC103273016 LOC103273016 ATRNL1 ATRNL1 FBLN7 FBLN7 SUSD1 SUSD1 BCAN BCAN LTBP4 LTBP4 ADGRE1 ADGRE1 HGFAC HGFAC ITGB4 ITGB4 ADAM33 ADAM33 DLK2 DLK2 HSPG2 HSPG2 FBLN1 FBLN1 LOC103261307 LOC103261307 LAMC1 LAMC1 PTGS1 PTGS1 LOC103265651 LOC103265651 FAT2 FAT2 CRELD1 CRELD1 NRXN1 NRXN1 ZAN ZAN MEGF6 MEGF6 PROS1 PROS1 EFEMP2 EFEMP2 TEK TEK DLK1 DLK1 LAMA5 LAMA5 HEG1 HEG1 NELL2 NELL2 BMP1 BMP1 SLIT1 SLIT1 TLL2 TLL2 LOC103250197 LOC103250197 LTBP2 LTBP2 MEGF11 MEGF11 LRP1 LRP1 CELSR2 CELSR2 ADAM2 ADAM2 NPNT NPNT FBN3 FBN3 SLIT2 SLIT2 PAMR1 PAMR1 VLDLR VLDLR CRB2 CRB2 F9 F9 SSPO SSPO F10 F10 UMODL1 UMODL1 EGFL8 EGFL8 SLIT3 SLIT3 C8A C8A ADAM22 ADAM22 RELN RELN SELE SELE NTNG1 NTNG1 LAMA4 LAMA4 CNTNAP5 CNTNAP5 LTBP1 LTBP1 ADAM9 ADAM9 TDGF1 TDGF1 IMPG2 IMPG2 PCSK5 PCSK5 TNXB TNXB LAMB4 LAMB4 SCUBE2 SCUBE2 TIE1 TIE1 NOTCH2 NOTCH2 NOTCH3 NOTCH3 ADAM28 ADAM28 PTGS2 PTGS2 HMCN1 HMCN1 CRB1 CRB1 CRELD2 CRELD2 DLL4 DLL4 STAB2 STAB2 PCSK6 PCSK6 STAB1 STAB1 OTOG OTOG HBEGF HBEGF ADGRE3 ADGRE3 TENM2 TENM2 MATN4 MATN4 THBS2 THBS2 LRP4 LRP4 LAMB1 LAMB1 AREG AREG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEFF2Tomoregulin-2. (340 aa)
LRP6Low-density lipoprotein receptor-related protein 6. (1603 aa)
VWCEVon Willebrand factor C and EGF domain-containing protein. (923 aa)
MUC13Mucin-13. (483 aa)
SNED1Sushi, nidogen and EGF-like domain-containing protein 1. (596 aa)
PLAUUrokinase-type plasminogen activator isoform X1. (433 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
MATN3Matrilin-3. (454 aa)
FAT4Protocadherin Fat 4. (2274 aa)
ASTN1Astrotactin-1 isoform X1. (1217 aa)
MEGF9Multiple epidermal growth factor-like domains protein 9. (538 aa)
ADGRL4Adhesion G protein-coupled receptor L4 isoform X2; Belongs to the G-protein coupled receptor 2 family. (690 aa)
MATN1Cartilage matrix protein. (447 aa)
EFEMP1EGF-containing fibulin-like extracellular matrix protein 1. (492 aa)
MEP1BMeprin A subunit. (701 aa)
PGAP6Transmembrane protein 8A. (765 aa)
ATRNAttractin. (1150 aa)
LOC103274258Delta and Notch-like epidermal growth factor-related receptor. (372 aa)
CD93Complement component C1q receptor. (648 aa)
FRAS1Extracellular matrix protein FRAS1. (3336 aa)
ADAM19Disintegrin and metalloproteinase domain-containing protein 19. (918 aa)
TENM3Teneurin-3. (2478 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (344 aa)
LOC103260743Contactin-associated protein-like 2. (536 aa)
TMEM8BTransmembrane protein 8B. (472 aa)
HHIPHedgehog-interacting protein. (700 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
LOC103251060Protein eyes shut homolog. (297 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
MASP2Mannan-binding lectin serine protease 2; Belongs to the peptidase S1 family. (662 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2796 aa)
EREGProepiregulin. (167 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1138 aa)
NID1Nidogen-1. (1248 aa)
CCBE1Collagen and calcium-binding EGF domain-containing protein 1. (337 aa)
NID2Nidogen-2. (1354 aa)
ITGBL1Integrin beta-like protein 1 isoform X1. (494 aa)
IMPG1LOW QUALITY PROTEIN: interphotoreceptor matrix proteoglycan 1. (753 aa)
TENM4Teneurin-4. (2602 aa)
LOC103256219LOW QUALITY PROTEIN: protein kinase C-binding protein NELL1-like. (404 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1039 aa)
VCANVersican core protein isoform X3. (1634 aa)
SCUBE1LOW QUALITY PROTEIN: signal peptide, CUB and EGF-like domain-containing protein 1. (826 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
VWA2Von Willebrand factor A domain-containing protein 2. (756 aa)
LOC103271083Contactin-associated protein-like 3. (672 aa)
EGFLAMPikachurin isoform X2. (1017 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (563 aa)
VWDEVon Willebrand factor D and EGF domain-containing protein. (1570 aa)
THBS1Thrombospondin-1. (1178 aa)
EGFL6Epidermal growth factor-like protein 6. (555 aa)
CNTNAP1Contactin-associated protein 1. (1310 aa)
CUBNCubilin. (3621 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3. (953 aa)
SCARF2Scavenger receptor class F member 2. (501 aa)
BTCProbetacellulin. (178 aa)
LAMA1Laminin subunit alpha-1. (3075 aa)
HABP2Hyaluronan-binding protein 2. (558 aa)
TNNtenascin-N isoform X1. (1297 aa)
LAMA2Laminin subunit alpha-2. (2586 aa)
ADAM12Disintegrin and metalloproteinase domain-containing protein 12. (879 aa)
FAT1Protocadherin Fat 1. (4439 aa)
LRP1BLow-density lipoprotein receptor-related protein 1B. (4598 aa)
LAMC3Laminin subunit gamma-3. (1431 aa)
SELPP-selectin. (830 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1. (2970 aa)
MMRN1Multimerin-1. (1219 aa)
THBS4Thrombospondin-4. (865 aa)
LAMC2Laminin subunit gamma-2. (1191 aa)
TLL1Metalloendopeptidase. (998 aa)
MEP1AMeprin A subunit. (749 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
LOC103268533Low-density lipoprotein receptor-related protein 2-like. (1223 aa)
FBLN5Fibulin-5. (490 aa)
NOTCH4Neurogenic locus notch homolog protein 4. (1999 aa)
UMODUromodulin. (687 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform. (243 aa)
LOC103250642Complement C1r-A subcomponent-like. (326 aa)
CNTNAP4Contactin-associated protein-like 4 isoform X2. (1308 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
ACANAggrecan core protein. (2147 aa)
CD248Endosialin. (661 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa)
LOC103251212Neurexin-3-like. (302 aa)
MATN2Matrilin-2 isoform X1. (956 aa)
FBN2Fibrillin-2. (2912 aa)
PROZVitamin K-dependent protein Z; Belongs to the peptidase S1 family. (393 aa)
EPGNEpigen isoform X1. (153 aa)
TNRLOW QUALITY PROTEIN: tenascin-R. (1359 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8. (801 aa)
LAMB3Laminin subunit beta-3. (1170 aa)
SCARF1Scavenger receptor class F member 1. (712 aa)
HMCN2Hemicentin-2. (537 aa)
LOC103275819Neurexin-1-like. (293 aa)
OIT3Oncoprotein-induced transcript 3 protein. (545 aa)
TNCTenascin isoform X1. (2201 aa)
EGFL7Epidermal growth factor-like protein 7. (268 aa)
AGRNLOW QUALITY PROTEIN: agrin. (1908 aa)
THBS3Thrombospondin-3 isoform X1. (950 aa)
LDLRLow-density lipoprotein receptor. (668 aa)
LOC103277266LOW QUALITY PROTEIN: neurocan core protein-like. (1021 aa)
MSANTD3-TMEFF1Tomoregulin-1 isoform X1. (454 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (728 aa)
WIF1Wnt inhibitory factor 1. (452 aa)
MEGF8Multiple epidermal growth factor-like domains protein 8. (2836 aa)
MALRD1MAM and LDL-receptor class A domain-containing protein 1. (1453 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1615 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (514 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15. (837 aa)
LOC103273016Protein crumbs homolog 1-like. (398 aa)
ATRNL1Attractin-like protein 1. (403 aa)
FBLN7Fibulin-7. (415 aa)
SUSD1Sushi domain-containing protein 1. (729 aa)
BCANBrevican core protein. (903 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4. (1507 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (929 aa)
HGFACHepatocyte growth factor activator. (489 aa)
ITGB4Integrin beta. (1638 aa)
ADAM33Disintegrin and metalloproteinase domain-containing protein 33. (744 aa)
DLK2Protein delta homolog 2 isoform X1. (382 aa)
HSPG2Basement membrane-specific heparan sulfate proteoglycan core protein. (4355 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (706 aa)
LOC103261307Laminin subunit alpha-3. (482 aa)
LAMC1Laminin subunit gamma-1. (1593 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (629 aa)
LOC103265651C-type lectin domain family 18 member A. (442 aa)
FAT2Protocadherin Fat 2. (4308 aa)
CRELD1Cysteine-rich with EGF-like domain protein 1. (420 aa)
NRXN1Neurexin-1 isoform X5. (1229 aa)
ZANLOW QUALITY PROTEIN: zonadhesin. (2533 aa)
MEGF6Multiple epidermal growth factor-like domains protein 6. (1498 aa)
PROS1Vitamin K-dependent protein S. (675 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2. (443 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
DLK1Protein delta homolog 1. (390 aa)
LAMA5Laminin subunit alpha-5. (3488 aa)
HEG1Protein HEG homolog 1. (138 aa)
NELL2Protein kinase C-binding protein NELL2 isoform X1. (112 aa)
BMP1Metalloendopeptidase. (945 aa)
SLIT1LOW QUALITY PROTEIN: slit homolog 1 protein-like. (1014 aa)
TLL2Metalloendopeptidase. (997 aa)
LOC103250197LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 21-like. (719 aa)
LTBP2Latent-transforming growth factor beta-binding protein 2. (1622 aa)
MEGF11Multiple epidermal growth factor-like domains protein 11. (1122 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4519 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2649 aa)
ADAM2Disintegrin and metalloproteinase domain-containing protein 2. (736 aa)
NPNTNephronectin isoform X1. (610 aa)
FBN3Fibrillin-3. (2244 aa)
SLIT2Slit homolog 2 protein isoform X1. (1542 aa)
PAMR1Inactive serine protease PAMR1 isoform X1; Belongs to the peptidase S1 family. (736 aa)
VLDLRVery low-density lipoprotein receptor. (868 aa)
CRB2Protein crumbs homolog 2. (1092 aa)
F9Coagulation factor IX isoform X1. (461 aa)
SSPOSCO-spondin. (5128 aa)
F10Coagulation factor X isoform X1. (492 aa)
UMODL1Uromodulin-like 1 isoform X1. (1452 aa)
EGFL8LOW QUALITY PROTEIN: uncharacterized protein LOC103271308. (279 aa)
SLIT3Slit homolog 3 protein. (1491 aa)
C8AComplement component C8 alpha chain. (586 aa)
ADAM22Disintegrin and metalloproteinase domain-containing protein 22. (824 aa)
RELNReelin. (3443 aa)
SELEE-selectin. (611 aa)
NTNG1netrin-G1. (403 aa)
LAMA4Laminin subunit alpha-4. (1777 aa)
CNTNAP5Contactin-associated protein-like 5. (1306 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1. (1011 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9. (795 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1202 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1824 aa)
TNXBtenascin-X. (4064 aa)
LAMB4Laminin subunit beta-4. (1759 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2. (999 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (2211 aa)
NOTCH3Neurogenic locus notch homolog protein 3. (2169 aa)
ADAM28Disintegrin and metalloproteinase domain-containing protein 28-like. (666 aa)
PTGS2Prostaglandin G/H synthase 2. (604 aa)
HMCN1Hemicentin-1. (5635 aa)
CRB1Protein crumbs homolog 1. (674 aa)
CRELD2Cysteine-rich with EGF-like domain protein 2 isoform X1. (390 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
STAB2Stabilin-2. (2166 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (969 aa)
STAB1Stabilin-1. (2571 aa)
OTOGOtogelin. (2926 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
ADGRE3Adhesion G protein-coupled receptor E3; Belongs to the G-protein coupled receptor 2 family. (646 aa)
TENM2Teneurin-2 isoform X1. (2653 aa)
MATN4Matrilin-4 isoform X1. (624 aa)
THBS2Thrombospondin-2. (1171 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1912 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
AREGAmphiregulin isoform X1. (270 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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