STRINGSTRING
TNK2 TNK2 WNK1 WNK1 DSTYK DSTYK EPHB3 EPHB3 SYK SYK EPHA6 EPHA6 EPHA4 EPHA4 AXL AXL TEC TEC BMPR1A BMPR1A TEK TEK FES FES TESK2 TESK2 DDR1 DDR1 LTK LTK LCK LCK FGFR1 FGFR1 ABL2 ABL2 CSK CSK INSR INSR INSRR INSRR HCK HCK ILK ILK MAP3K10 MAP3K10 TEX14 TEX14 LIMK1 LIMK1 PTK2 PTK2 FGFR3 FGFR3 EPHB4 EPHB4 MAP3K11 MAP3K11 ACVR1 ACVR1 BLK BLK EPHB6 EPHB6 NTRK1 NTRK1 MST1R MST1R ACVR1C ACVR1C LOC103267688 LOC103267688 TESK1 TESK1 NEK6 NEK6 PDGFRB PDGFRB RIPK4 RIPK4 ARAF ARAF MAP3K7 MAP3K7 NEK7 NEK7 SRC SRC MUSK MUSK LIMK2 LIMK2 MLKL MLKL EPHA7 EPHA7 SRMS SRMS PTK2B PTK2B TYK2 TYK2 CSF1R CSF1R BMX BMX FLT3 FLT3 ANKK1 ANKK1 TXK TXK GUCY2F GUCY2F ZAP70 ZAP70 EPHA5 EPHA5 LOC103250516 LOC103250516 TIE1 TIE1 MAP3K20 MAP3K20 PTK7 PTK7 KSR1 KSR1 MERTK MERTK FYN FYN KSR2 KSR2 LOC103249947 LOC103249947 ERBB2 ERBB2 POMK POMK LOC103264991 LOC103264991 LOC103258924 LOC103258924 FGR FGR EPHA8 EPHA8 MAP3K12 MAP3K12 NRBP1 NRBP1 PTK6 PTK6 AATK AATK KIT KIT PDGFRA PDGFRA EPHA1 EPHA1 MAP3K9 MAP3K9 EGFR EGFR RIPK2 RIPK2 FRK FRK LOC103271002 LOC103271002 JAK1 JAK1 GUCY2C GUCY2C RET RET RAF1 RAF1 TNK1 TNK1 ERBB4 ERBB4 LOC103261652 LOC103261652 GUCY2D GUCY2D BTK BTK BRAF BRAF EPHA2 EPHA2 FER FER ALK ALK ROR1 ROR1 STYK1 STYK1 FGFR2 FGFR2 JAK2 JAK2 RIPK1 RIPK1 EPHA10 EPHA10 MAP3K21 MAP3K21 LYN LYN EPHB1 EPHB1 MET MET ACVRL1 ACVRL1 ABL1 ABL1 TGFBR2 TGFBR2 IRAK4 IRAK4 ITK ITK IGF1R IGF1R LOC103259681 LOC103259681 BMPR1B BMPR1B NPR2 NPR2 YES1 YES1 RYK RYK EPHB2 EPHB2 KDR KDR LMTK2 LMTK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNK2Activated CDC42 kinase 1 isoform X5; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1063 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X1. (2624 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform X1. (929 aa)
EPHB3Ephrin type-B receptor 3. (1049 aa)
SYKTyrosine-protein kinase. (634 aa)
EPHA6Ephrin type-A receptor 6. (367 aa)
EPHA4Ephrin type-A receptor 4 isoform X2. (949 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (894 aa)
TECTyrosine-protein kinase. (631 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
TESK2LOW QUALITY PROTEIN: dual specificity testis-specific protein kinase 2. (359 aa)
DDR1Epithelial discoidin domain-containing receptor 1 isoform X1. (913 aa)
LTKTyrosine-protein kinase receptor. (780 aa)
LCKTyrosine-protein kinase. (524 aa)
FGFR1Fibroblast growth factor receptor. (832 aa)
ABL2Tyrosine-protein kinase. (1182 aa)
CSKTyrosine-protein kinase. (450 aa)
INSRTyrosine-protein kinase receptor. (1356 aa)
INSRRTyrosine-protein kinase receptor. (1284 aa)
HCKTyrosine-protein kinase. (546 aa)
ILKIntegrin-linked protein kinase isoform X2. (465 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase 10. (891 aa)
TEX14Inactive serine/threonine-protein kinase TEX14 isoform X2. (1497 aa)
LIMK1LIM domain kinase 1 isoform X1. (663 aa)
PTK2Focal adhesion kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
FGFR3Fibroblast growth factor receptor. (745 aa)
EPHB4Ephrin type-B receptor 4 isoform X1. (987 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (745 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BLKTyrosine-protein kinase. (388 aa)
EPHB6Ephrin type-B receptor 6. (1025 aa)
NTRK1High affinity nerve growth factor receptor. (721 aa)
MST1RMacrophage-stimulating protein receptor isoform X1. (1405 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
LOC103267688Inactive serine/threonine-protein kinase VRK3-like isoform X2. (419 aa)
TESK1Dual specificity testis-specific protein kinase 1. (626 aa)
NEK6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (318 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
RIPK4Receptor-interacting serine/threonine-protein kinase 4. (771 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (611 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
NEK7Serine/threonine-protein kinase Nek7; Belongs to the protein kinase superfamily. (302 aa)
SRCTyrosine-protein kinase. (542 aa)
MUSKReceptor protein-tyrosine kinase. (741 aa)
LIMK2LIM domain kinase 2 isoform X1. (645 aa)
MLKLMixed lineage kinase domain-like protein. (478 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (1090 aa)
SRMSTyrosine-protein kinase. (424 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
TYK2Tyrosine-protein kinase. (869 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (965 aa)
BMXTyrosine-protein kinase. (653 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (980 aa)
ANKK1Ankyrin repeat and protein kinase domain-containing protein 1. (765 aa)
TXKTyrosine-protein kinase. (524 aa)
GUCY2FGuanylate cyclase. (1108 aa)
ZAP70Tyrosine-protein kinase ZAP-70. (556 aa)
EPHA5Ephrin type-A receptor 5 isoform X1. (1038 aa)
LOC103250516Discoidin domain-containing receptor 2-like. (168 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (801 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
KSR1LOW QUALITY PROTEIN: kinase suppressor of Ras 1. (864 aa)
MERTKTyrosine-protein kinase Mer. (823 aa)
FYNTyrosine-protein kinase. (537 aa)
KSR2Kinase suppressor of Ras 2. (952 aa)
LOC103249947Tyrosine-protein kinase receptor. (662 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
POMKProtein O-mannose kinase. (297 aa)
LOC103264991Vascular endothelial growth factor receptor 1 isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (431 aa)
LOC103258924Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (142 aa)
FGRTyrosine-protein kinase. (526 aa)
EPHA8Ephrin type-A receptor 8. (998 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
NRBP1Nuclear receptor-binding protein isoform X1. (540 aa)
PTK6Tyrosine-protein kinase. (450 aa)
AATKSerine/threonine-protein kinase LMTK1. (1072 aa)
KITMast/stem cell growth factor receptor Kit; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (953 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa)
EPHA1Ephrin type-A receptor 1. (961 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase. (1095 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2 isoform X1. (539 aa)
FRKTyrosine-protein kinase. (496 aa)
LOC103271002Receptor tyrosine-protein kinase erbB-3. (580 aa)
JAK1Tyrosine-protein kinase. (1140 aa)
GUCY2CGuanylate cyclase. (1073 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1092 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (668 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1 isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (667 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
LOC103261652LOW QUALITY PROTEIN: serine/threonine-protein kinase TNNI3K-like. (822 aa)
GUCY2DGuanylate cyclase. (1089 aa)
BTKTyrosine-protein kinase. (659 aa)
BRAFSerine/threonine-protein kinase B-raf. (760 aa)
EPHA2LOW QUALITY PROTEIN: ephrin type-A receptor 2. (917 aa)
FERTyrosine-protein kinase. (647 aa)
ALKTyrosine-protein kinase receptor. (1397 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
STYK1Tyrosine-protein kinase STYK1. (427 aa)
FGFR2Fibroblast growth factor receptor 2 isoform X1. (615 aa)
JAK2Tyrosine-protein kinase. (1131 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (671 aa)
EPHA10LOW QUALITY PROTEIN: ephrin type-A receptor 10. (945 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase 21. (760 aa)
LYNTyrosine-protein kinase. (512 aa)
EPHB1Ephrin type-B receptor 1. (964 aa)
METHepatocyte growth factor receptor isoform X1. (1415 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (558 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
ITKTyrosine-protein kinase. (620 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
LOC103259681Ephrin type-A receptor 3. (310 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (480 aa)
NPR2Guanylate cyclase. (1047 aa)
YES1Tyrosine-protein kinase. (546 aa)
RYKTyrosine-protein kinase RYK isoform X2. (529 aa)
EPHB2LOW QUALITY PROTEIN: ephrin type-B receptor 2. (808 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
LMTK2Serine/threonine-protein kinase LMTK2 isoform X2. (1501 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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