(26 nodes) Transforming growth factor-beta, C-terminal network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSPN	Persephin. (107 aa)
	LOC103269949	Left-right determination factor. (366 aa)
	BMP2	Bone morphogenetic protein 2. (398 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	BMP5	Bone morphogenetic protein 5 isoform X1. (454 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	INHBE	Inhibin beta E chain. (354 aa)
	BMP6	Bone morphogenetic protein 6. (513 aa)
	BMP3	Bone morphogenetic protein 3. (409 aa)
	NODAL	Nodal homolog. (332 aa)
	MSTN	Growth/differentiation factor 8. (376 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (344 aa)
	GDF9	Growth/differentiation factor 9 isoform X1. (454 aa)
	GDF6	Growth/differentiation factor 6. (457 aa)
	GDF2	Growth/differentiation factor 2. (428 aa)
	GDNF	Glial cell line-derived neurotrophic factor isoform X3. (211 aa)
	INHBC	Inhibin beta C chain. (348 aa)
	GDF5	Growth/differentiation factor 5. (499 aa)
	INHBA	Inhibin beta A chain. (426 aa)
	GDF10	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (476 aa)
	INHA	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (367 aa)
	ARTN	Artemin. (154 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	GDF11	Growth/differentiation factor 11. (258 aa)
	BMP4	Bone morphogenetic protein 4 isoform X1. (409 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARTN	GDNF	ENSTSYP00000030529	ENSTSYP00000012753	Artemin.	Glial cell line-derived neurotrophic factor isoform X3.	0.579
ARTN	PSPN	ENSTSYP00000030529	ENSTSYP00000029830	Artemin.	Persephin.	0.533
BMP10	BMP2	ENSTSYP00000001318	ENSTSYP00000034511	Bone morphogenetic protein 10.	Bone morphogenetic protein 2.	0.444
BMP10	BMP4	ENSTSYP00000001318	ENSTSYP00000026121	Bone morphogenetic protein 10.	Bone morphogenetic protein 4 isoform X1.	0.492
BMP10	BMP5	ENSTSYP00000001318	ENSTSYP00000000031	Bone morphogenetic protein 10.	Bone morphogenetic protein 5 isoform X1.	0.504
BMP10	BMP6	ENSTSYP00000001318	ENSTSYP00000003332	Bone morphogenetic protein 10.	Bone morphogenetic protein 6.	0.413
BMP10	BMP7	ENSTSYP00000001318	ENSTSYP00000034824	Bone morphogenetic protein 10.	Bone morphogenetic protein 7.	0.453
BMP10	GDF2	ENSTSYP00000001318	ENSTSYP00000011746	Bone morphogenetic protein 10.	Growth/differentiation factor 2.	0.758
BMP10	GDF5	ENSTSYP00000001318	ENSTSYP00000016066	Bone morphogenetic protein 10.	Growth/differentiation factor 5.	0.468
BMP10	GDF6	ENSTSYP00000001318	ENSTSYP00000011187	Bone morphogenetic protein 10.	Growth/differentiation factor 6.	0.467
BMP2	BMP10	ENSTSYP00000034511	ENSTSYP00000001318	Bone morphogenetic protein 2.	Bone morphogenetic protein 10.	0.444
BMP2	BMP3	ENSTSYP00000034511	ENSTSYP00000003612	Bone morphogenetic protein 2.	Bone morphogenetic protein 3.	0.820
BMP2	BMP4	ENSTSYP00000034511	ENSTSYP00000026121	Bone morphogenetic protein 2.	Bone morphogenetic protein 4 isoform X1.	0.887
BMP2	BMP5	ENSTSYP00000034511	ENSTSYP00000000031	Bone morphogenetic protein 2.	Bone morphogenetic protein 5 isoform X1.	0.867
BMP2	BMP6	ENSTSYP00000034511	ENSTSYP00000003332	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.939
BMP2	BMP7	ENSTSYP00000034511	ENSTSYP00000034824	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.925
BMP2	GDF2	ENSTSYP00000034511	ENSTSYP00000011746	Bone morphogenetic protein 2.	Growth/differentiation factor 2.	0.492
BMP2	GDF5	ENSTSYP00000034511	ENSTSYP00000016066	Bone morphogenetic protein 2.	Growth/differentiation factor 5.	0.814
BMP2	GDF6	ENSTSYP00000034511	ENSTSYP00000011187	Bone morphogenetic protein 2.	Growth/differentiation factor 6.	0.705
BMP2	NODAL	ENSTSYP00000034511	ENSTSYP00000004774	Bone morphogenetic protein 2.	Nodal homolog.	0.682