STRINGSTRING
SVEP1 SVEP1 EPHA10 EPHA10 LRP1B LRP1B EPHB1 EPHB1 LAMA2 LAMA2 SCUBE3 SCUBE3 CUBN CUBN EGFL6 EGFL6 IGF1R IGF1R KIAA1324L KIAA1324L CCN6 CCN6 JAG1 JAG1 SCUBE1 SCUBE1 LOC103256219 LOC103256219 EPHB2 EPHB2 IGFBP4 IGFBP4 CRIM1 CRIM1 NID2 NID2 EPHA1 EPHA1 NID1 NID1 DLL1 DLL1 EGFR EGFR FRAS1 FRAS1 CD93 CD93 LOC103271002 LOC103271002 LOC103274258 LOC103274258 WISP1 WISP1 ERBB4 ERBB4 EFEMP1 EFEMP1 MATN3 MATN3 SNED1 SNED1 MUC13 MUC13 VWCE VWCE TMEM67 TMEM67 LOC103268533 LOC103268533 EGF EGF BRINP3 BRINP3 TG TG C9 C9 EPHA2 EPHA2 RSPO3 RSPO3 LRP4 LRP4 IGFBP1 IGFBP1 PCSK6 PCSK6 DLL4 DLL4 CRELD2 CRELD2 HMCN1 HMCN1 NOTCH3 NOTCH3 NOTCH2 NOTCH2 EPHA5 EPHA5 IGFBP6 IGFBP6 SCUBE2 SCUBE2 PCSK5 PCSK5 LTBP1 LTBP1 SLIT3 SLIT3 UMODL1 UMODL1 ERBB2 ERBB2 RSPO1 RSPO1 CRB2 CRB2 FBN3 FBN3 NPNT NPNT BRINP2 BRINP2 LRP1 LRP1 LTBP2 LTBP2 SLIT1 SLIT1 KIAA1324 KIAA1324 TEK TEK EFEMP2 EFEMP2 PROS1 PROS1 TNFRSF9 TNFRSF9 MEGF6 MEGF6 FURIN FURIN CRELD1 CRELD1 FBLN1 FBLN1 INSR INSR INSRR INSRR RSPO2 RSPO2 LOC103275563 LOC103275563 ADGRE1 ADGRE1 LTBP4 LTBP4 EPHB4 EPHB4 LOC103273016 LOC103273016 RSPO4 RSPO4 LOC103256375 LOC103256375 LDLR LDLR EGFL7 EGFL7 HMCN2 HMCN2 LOC103254746 LOC103254746 LOC103267690 LOC103267690 FBN2 FBN2 MATN2 MATN2 JAG2 JAG2 WISP2 WISP2 CD248 CD248 NOTCH1 NOTCH1 ESM1 ESM1 UMOD UMOD NOTCH4 NOTCH4 EPHA7 EPHA7 FBLN5 FBLN5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1. (2970 aa)
EPHA10LOW QUALITY PROTEIN: ephrin type-A receptor 10. (945 aa)
LRP1BLow-density lipoprotein receptor-related protein 1B. (4598 aa)
EPHB1Ephrin type-B receptor 1. (964 aa)
LAMA2Laminin subunit alpha-2. (2586 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 3. (953 aa)
CUBNCubilin. (3621 aa)
EGFL6Epidermal growth factor-like protein 6. (555 aa)
IGF1RTyrosine-protein kinase receptor. (1335 aa)
KIAA1324LUPF0577 protein KIAA1324-like homolog isoform X2. (843 aa)
CCN6WNT1-inducible-signaling pathway protein 3. (369 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1214 aa)
SCUBE1LOW QUALITY PROTEIN: signal peptide, CUB and EGF-like domain-containing protein 1. (826 aa)
LOC103256219LOW QUALITY PROTEIN: protein kinase C-binding protein NELL1-like. (404 aa)
EPHB2LOW QUALITY PROTEIN: ephrin type-B receptor 2. (808 aa)
IGFBP4Insulin-like growth factor-binding protein 4. (258 aa)
CRIM1Cysteine-rich motor neuron 1 protein isoform X1. (1037 aa)
NID2Nidogen-2. (1354 aa)
EPHA1Ephrin type-A receptor 1. (961 aa)
NID1Nidogen-1. (1248 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (741 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
FRAS1Extracellular matrix protein FRAS1. (3336 aa)
CD93Complement component C1q receptor. (648 aa)
LOC103271002Receptor tyrosine-protein kinase erbB-3. (580 aa)
LOC103274258Delta and Notch-like epidermal growth factor-related receptor. (372 aa)
WISP1WNT1-inducible-signaling pathway protein 1. (367 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
EFEMP1EGF-containing fibulin-like extracellular matrix protein 1. (492 aa)
MATN3Matrilin-3. (454 aa)
SNED1Sushi, nidogen and EGF-like domain-containing protein 1. (596 aa)
MUC13Mucin-13. (483 aa)
VWCEVon Willebrand factor C and EGF domain-containing protein. (923 aa)
TMEM67Meckelin. (995 aa)
LOC103268533Low-density lipoprotein receptor-related protein 2-like. (1223 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
BRINP3BMP/retinoic acid-inducible neural-specific protein 3 isoform X1. (766 aa)
TGThyroglobulin. (2767 aa)
C9Complement component C9. (559 aa)
EPHA2LOW QUALITY PROTEIN: ephrin type-A receptor 2. (917 aa)
RSPO3R-spondin-3. (244 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1912 aa)
IGFBP1Insulin-like growth factor-binding protein 1. (247 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (969 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
CRELD2Cysteine-rich with EGF-like domain protein 2 isoform X1. (390 aa)
HMCN1Hemicentin-1. (5635 aa)
NOTCH3Neurogenic locus notch homolog protein 3. (2169 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (2211 aa)
EPHA5Ephrin type-A receptor 5 isoform X1. (1038 aa)
IGFBP6LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 6. (237 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2. (999 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1824 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1. (1011 aa)
SLIT3Slit homolog 3 protein. (1491 aa)
UMODL1Uromodulin-like 1 isoform X1. (1452 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
RSPO1R-spondin-1. (263 aa)
CRB2Protein crumbs homolog 2. (1092 aa)
FBN3Fibrillin-3. (2244 aa)
NPNTNephronectin isoform X1. (610 aa)
BRINP2BMP/retinoic acid-inducible neural-specific protein 2. (560 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4519 aa)
LTBP2Latent-transforming growth factor beta-binding protein 2. (1622 aa)
SLIT1LOW QUALITY PROTEIN: slit homolog 1 protein-like. (1014 aa)
KIAA1324UPF0577 protein KIAA1324 homolog isoform X1. (962 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
EFEMP2EGF-containing fibulin-like extracellular matrix protein 2. (443 aa)
PROS1Vitamin K-dependent protein S. (675 aa)
TNFRSF9Tumor necrosis factor receptor superfamily member 9. (62 aa)
MEGF6Multiple epidermal growth factor-like domains protein 6. (1498 aa)
FURINFurin; Belongs to the peptidase S8 family. (794 aa)
CRELD1Cysteine-rich with EGF-like domain protein 1. (420 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (706 aa)
INSRTyrosine-protein kinase receptor. (1356 aa)
INSRRTyrosine-protein kinase receptor. (1284 aa)
RSPO2R-spondin-2. (211 aa)
LOC103275563Receptor tyrosine-protein kinase erbB-3. (169 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (929 aa)
LTBP4Latent-transforming growth factor beta-binding protein 4. (1507 aa)
EPHB4Ephrin type-B receptor 4 isoform X1. (987 aa)
LOC103273016Protein crumbs homolog 1-like. (398 aa)
RSPO4R-spondin-4 isoform X1. (234 aa)
LOC103256375Ephrin type-A receptor 3-like. (332 aa)
LDLRLow-density lipoprotein receptor. (668 aa)
EGFL7Epidermal growth factor-like protein 7. (268 aa)
HMCN2Hemicentin-2. (537 aa)
LOC103254746Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1-like. (599 aa)
LOC103267690LOW QUALITY PROTEIN: ephrin type-A receptor 6-like. (267 aa)
FBN2Fibrillin-2. (2912 aa)
MATN2Matrilin-2 isoform X1. (956 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa)
WISP2WNT1-inducible-signaling pathway protein 2. (250 aa)
CD248Endosialin. (661 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2339 aa)
ESM1Endothelial cell-specific molecule 1 isoform X1. (185 aa)
UMODUromodulin. (687 aa)
NOTCH4Neurogenic locus notch homolog protein 4. (1999 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (1090 aa)
FBLN5Fibulin-5. (490 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
Server load: low (36%) [HD]