STRINGSTRING
TLE3 TLE3 WDHD1 WDHD1 STRN3 STRN3 AAAS AAAS WDFY2 WDFY2 PAFAH1B1 PAFAH1B1 PEX7 PEX7 EIPR1 EIPR1 DDB2 DDB2 WDSUB1 WDSUB1 AAMP AAMP RBBP7 RBBP7 DAW1 DAW1 UTP18 UTP18 CSTF1 CSTF1 WDR36 WDR36 DCAF13 DCAF13 TLE4 TLE4 WDR1 WDR1 COP1 COP1 PWP1 PWP1 KIF21A KIF21A WDR17 WDR17 WDR49 WDR49 CFAP52 CFAP52 WDR86 WDR86 EED EED WDR7 WDR7 RBBP4 RBBP4 WDFY1 WDFY1 GTF3C2 GTF3C2 WDR72 WDR72 DTL DTL TAF5L TAF5L TAF5 TAF5 TBL1XR1 TBL1XR1 SMU1 SMU1 UTP15 UTP15 POC1A POC1A DCAF7 DCAF7 WDR12 WDR12 WDR53 WDR53 CORO1C CORO1C PWP2 PWP2 NUP37 NUP37 WDR41 WDR41 TBL1X TBL1X WDR31 WDR31 SNRNP40 SNRNP40 PRPF4 PRPF4 CIAO1 CIAO1 GEMIN5 GEMIN5 BRWD1 BRWD1 STRN STRN WDR11 WDR11 NEDD1 NEDD1 GNB5 GNB5 COPA COPA CDC20B CDC20B PHIP PHIP LYST LYST ERCC8 ERCC8 DCAF12 DCAF12 WDR61 WDR61 WDR38 WDR38 CORO6 CORO6 CDC40 CDC40 CORO2A CORO2A TRAF7 TRAF7 GNB1 GNB1 SCAP SCAP FBXW11 FBXW11 BRWD3 BRWD3 WDR83 WDR83 HERC1 HERC1 WDR59 WDR59 DPH7 DPH7 LOC103273837 LOC103273837 NLE1 NLE1 ATG16L1 ATG16L1 CORO1A CORO1A CORO1B CORO1B WDR37 WDR37 KATNB1 KATNB1 LOC103273693 LOC103273693 WDR55 WDR55 STRN4 STRN4 WDR24 WDR24 WDR5 WDR5 WDR97 WDR97 GRWD1 GRWD1 BTRC BTRC PLRG1 PLRG1 FBXW7 FBXW7 GNB4 GNB4 LOC103250844 LOC103250844 POC1B POC1B TLE2 TLE2 EIF3I EIF3I APAF1 APAF1 TLE1 TLE1 RAE1 RAE1 CFAP44 CFAP44 LOC103256196 LOC103256196 ATG16L2 ATG16L2 WDR77 WDR77 FBXW9 FBXW9 NUP43 NUP43 KIF21B KIF21B PAK1IP1 PAK1IP1 WDR88 WDR88 BOP1 BOP1 THOC6 THOC6 FBXW2 FBXW2 FZR1 FZR1 RRP9 RRP9 LRWD1 LRWD1 PRPF19 PRPF19 WDR90 WDR90 MLST8 MLST8 AMBRA1 AMBRA1 WDR47 WDR47 CORO2B CORO2B LOC103267945 LOC103267945 DENND3 DENND3 WDR3 WDR3 GNB2 GNB2 TBL3 TBL3 GNB3 GNB3 WSB1 WSB1 LOC103254854 LOC103254854 WSB2 WSB2 WDFY3 WDFY3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TLE3Transducin-like enhancer protein 3 isoform X3. (778 aa)
WDHD1WD repeat and HMG-box DNA-binding protein 1. (1118 aa)
STRN3Striatin-3 isoform X1. (797 aa)
AAASAladin isoform X1. (545 aa)
WDFY2WD repeat and FYVE domain-containing protein 2. (400 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
EIPR1Protein TSSC1. (387 aa)
DDB2DNA damage-binding protein 2 isoform X1. (415 aa)
WDSUB1WD repeat, SAM and U-box domain-containing protein 1 isoform X1. (476 aa)
AAMPAngio-associated migratory cell protein isoform X2. (451 aa)
RBBP7Histone-binding protein RBBP7. (469 aa)
DAW1Dynein assembly factor with WDR repeat domains 1. (415 aa)
UTP18U3 small nucleolar RNA-associated protein 18 homolog isoform X1. (556 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
WDR36LOW QUALITY PROTEIN: WD repeat-containing protein 36. (895 aa)
DCAF13DDB1- and CUL4-associated factor 13 isoform X1. (445 aa)
TLE4Transducin-like enhancer protein 4 isoform X1. (749 aa)
WDR1WD repeat-containing protein 1. (598 aa)
COP1E3 ubiquitin-protein ligase RFWD2 isoform X1. (731 aa)
PWP1Periodic tryptophan protein 1 homolog isoform X1. (499 aa)
KIF21AKinesin-like protein KIF21A isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1652 aa)
WDR17WD repeat-containing protein 17 isoform X1. (1316 aa)
WDR49LOW QUALITY PROTEIN: WD repeat-containing protein 49. (655 aa)
CFAP52Cilia- and flagella-associated protein 52 isoform X1. (620 aa)
WDR86WD repeat-containing protein 86. (325 aa)
EEDPolycomb protein EED isoform X1. (466 aa)
WDR7WD repeat-containing protein 7. (990 aa)
RBBP4Histone-binding protein RBBP4 isoform X1. (425 aa)
WDFY1WD repeat and FYVE domain-containing protein 1 isoform X1. (410 aa)
GTF3C2General transcription factor 3C polypeptide 2. (911 aa)
WDR72WD repeat-containing protein 72. (666 aa)
DTLDenticleless protein homolog isoform X1. (729 aa)
TAF5LTAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L. (589 aa)
TAF5Transcription initiation factor TFIID subunit 5. (500 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1 isoform X1. (514 aa)
SMU1WD40 repeat-containing protein SMU1. (513 aa)
UTP15U3 small nucleolar RNA-associated protein 15 homolog isoform X1. (518 aa)
POC1APOC1 centriolar protein homolog A isoform X1. (407 aa)
DCAF7LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 7. (296 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
WDR53WD repeat-containing protein 53. (360 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (496 aa)
PWP2Periodic tryptophan protein 2 homolog. (915 aa)
NUP37Nucleoporin Nup37. (326 aa)
WDR41WD repeat-containing protein 41. (436 aa)
TBL1XF-box-like/WD repeat-containing protein TBL1X. (572 aa)
WDR31WD repeat-containing protein 31. (367 aa)
SNRNP40U5 small nuclear ribonucleoprotein 40 kDa protein isoform X1. (358 aa)
PRPF4U4/U6 small nuclear ribonucleoprotein Prp4 isoform X2. (536 aa)
CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)
GEMIN5Gem-associated protein 5 isoform X1. (1515 aa)
BRWD1Bromodomain and WD repeat-containing protein 1 isoform X1. (2325 aa)
STRNStriatin isoform X1. (780 aa)
WDR11WD repeat-containing protein 11. (1224 aa)
NEDD1Protein NEDD1. (662 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (396 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa)
CDC20BCell division cycle protein 20 homolog B isoform X1. (516 aa)
PHIPPH-interacting protein. (1674 aa)
LYSTLysosomal-trafficking regulator. (3802 aa)
ERCC8DNA excision repair protein ERCC-8 isoform X1. (396 aa)
DCAF12DDB1- and CUL4-associated factor 12. (453 aa)
WDR61WD repeat-containing protein 61 isoform X1. (305 aa)
WDR38WD repeat-containing protein 38 isoform X1. (312 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (423 aa)
CDC40pre-mRNA-processing factor 17. (579 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (458 aa)
TRAF7E3 ubiquitin-protein ligase TRAF7. (685 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1. (340 aa)
SCAPSterol regulatory element-binding protein cleavage-activating protein isoform X1. (535 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (533 aa)
BRWD3Bromodomain and WD repeat-containing protein 3 isoform X1. (1801 aa)
WDR83WD repeat domain-containing protein 83. (315 aa)
HERC1Probable E3 ubiquitin-protein ligase HERC1 isoform X1. (4865 aa)
WDR59GATOR complex protein WDR59. (974 aa)
DPH7Diphthine methyltransferase isoform X1. (400 aa)
LOC103273837LOW QUALITY PROTEIN: histone-binding protein RBBP4-like. (404 aa)
NLE1Notchless protein homolog 1 isoform X1. (486 aa)
ATG16L1Autophagy-related protein 16-1 isoform X1. (623 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (486 aa)
WDR37WD repeat-containing protein 37 isoform X1. (496 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (659 aa)
LOC103273693Coronin; Belongs to the WD repeat coronin family. (762 aa)
WDR55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (382 aa)
STRN4Striatin-4 isoform X1. (760 aa)
WDR24GATOR complex protein WDR24. (790 aa)
WDR5WD repeat-containing protein 5-like. (241 aa)
WDR97LOW QUALITY PROTEIN: WD repeat-containing protein 97. (832 aa)
GRWD1Glutamate-rich WD repeat-containing protein 1. (446 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (589 aa)
PLRG1Pleiotropic regulator 1 isoform X2. (514 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (708 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC103250844WD repeat-containing protein 48. (134 aa)
POC1BPOC1 centriolar protein homolog B-like. (404 aa)
TLE2Transducin-like enhancer protein 2. (474 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1246 aa)
TLE1Transducin-like enhancer protein 1 isoform X3. (792 aa)
RAE1mRNA export factor. (521 aa)
CFAP44Cilia- and flagella-associated protein 44-like. (1661 aa)
LOC103256196LOW QUALITY PROTEIN: receptor of activated protein C kinase 1-like. (305 aa)
ATG16L2Autophagy-related protein 16-2. (621 aa)
WDR77Methylosome protein 50 isoform X2. (342 aa)
FBXW9F-box/WD repeat-containing protein 9. (458 aa)
NUP43Nucleoporin Nup43. (380 aa)
KIF21BKinesin-like protein KIF21B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1723 aa)
PAK1IP1P21-activated protein kinase-interacting protein 1. (406 aa)
WDR88WD repeat-containing protein 88-like. (286 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (739 aa)
THOC6THO complex subunit 6 homolog isoform X1. (341 aa)
FBXW2F-box/WD repeat-containing protein 2 isoform X2. (454 aa)
FZR1Fizzy-related protein homolog. (449 aa)
RRP9U3 small nucleolar RNA-interacting protein 2. (475 aa)
LRWD1Leucine-rich repeat and WD repeat-containing protein 1. (646 aa)
PRPF19pre-mRNA-processing factor 19. (505 aa)
WDR90LOW QUALITY PROTEIN: WD repeat-containing protein 90. (305 aa)
MLST8Target of rapamycin complex subunit LST8 isoform X2. (326 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1. (1299 aa)
WDR47WD repeat-containing protein 47. (919 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (494 aa)
LOC103267945Receptor of activated protein C kinase 1-like. (223 aa)
DENND3DENN domain-containing protein 3. (1283 aa)
WDR3WD repeat-containing protein 3. (945 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X3. (321 aa)
TBL3Transducin beta-like protein 3 isoform X1. (806 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
WSB1WD repeat and SOCS box-containing protein 1 isoform X1. (421 aa)
LOC103254854WD repeat- and FYVE domain-containing protein 4. (318 aa)
WSB2WD repeat and SOCS box-containing protein 2 isoform X1. (406 aa)
WDFY3WD repeat and FYVE domain-containing protein 3. (3528 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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