(16 nodes) Complement Clr-like EGF domain network (Carlito syrichta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SCUBE2	Signal peptide, CUB and EGF-like domain-containing protein 2. (999 aa)
	LRP1B	Low-density lipoprotein receptor-related protein 1B. (4598 aa)
	THBS1	Thrombospondin-1. (1178 aa)
	NID2	Nidogen-2. (1354 aa)
	NID1	Nidogen-1. (1248 aa)
	EFEMP1	EGF-containing fibulin-like extracellular matrix protein 1. (492 aa)
	MATN3	Matrilin-3. (454 aa)
	LRP4	Low-density lipoprotein receptor-related protein 4. (1912 aa)
	HMCN1	Hemicentin-1. (5635 aa)
	FBN3	Fibrillin-3. (2244 aa)
	LRP1	Prolow-density lipoprotein receptor-related protein 1. (4519 aa)
	EFEMP2	EGF-containing fibulin-like extracellular matrix protein 2. (443 aa)
	FBLN1	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (706 aa)
	HMCN2	Hemicentin-2. (537 aa)
	FBN2	Fibrillin-2. (2912 aa)
	FBLN5	Fibulin-5. (490 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFEMP1	FBLN1	ENSTSYP00000007576	ENSTSYP00000022573	EGF-containing fibulin-like extracellular matrix protein 1.	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	0.522
EFEMP1	FBLN5	ENSTSYP00000007576	ENSTSYP00000034673	EGF-containing fibulin-like extracellular matrix protein 1.	Fibulin-5.	0.516
EFEMP2	FBLN1	ENSTSYP00000019933	ENSTSYP00000022573	EGF-containing fibulin-like extracellular matrix protein 2.	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	0.505
EFEMP2	FBLN5	ENSTSYP00000019933	ENSTSYP00000034673	EGF-containing fibulin-like extracellular matrix protein 2.	Fibulin-5.	0.541
EFEMP2	HMCN2	ENSTSYP00000019933	ENSTSYP00000030085	EGF-containing fibulin-like extracellular matrix protein 2.	Hemicentin-2.	0.514
FBLN1	EFEMP1	ENSTSYP00000022573	ENSTSYP00000007576	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	EGF-containing fibulin-like extracellular matrix protein 1.	0.522
FBLN1	EFEMP2	ENSTSYP00000022573	ENSTSYP00000019933	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	EGF-containing fibulin-like extracellular matrix protein 2.	0.505
FBLN1	FBLN5	ENSTSYP00000022573	ENSTSYP00000034673	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	Fibulin-5.	0.472
FBLN1	NID1	ENSTSYP00000022573	ENSTSYP00000004503	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	Nidogen-1.	0.673
FBLN1	NID2	ENSTSYP00000022573	ENSTSYP00000004149	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	Nidogen-2.	0.542
FBLN5	EFEMP1	ENSTSYP00000034673	ENSTSYP00000007576	Fibulin-5.	EGF-containing fibulin-like extracellular matrix protein 1.	0.516
FBLN5	EFEMP2	ENSTSYP00000034673	ENSTSYP00000019933	Fibulin-5.	EGF-containing fibulin-like extracellular matrix protein 2.	0.541
FBLN5	FBLN1	ENSTSYP00000034673	ENSTSYP00000022573	Fibulin-5.	Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.	0.472
HMCN2	EFEMP2	ENSTSYP00000030085	ENSTSYP00000019933	Hemicentin-2.	EGF-containing fibulin-like extracellular matrix protein 2.	0.514
LRP1	LRP4	ENSTSYP00000017567	ENSTSYP00000009906	Prolow-density lipoprotein receptor-related protein 1.	Low-density lipoprotein receptor-related protein 4.	0.816
LRP1	THBS1	ENSTSYP00000017567	ENSTSYP00000002362	Prolow-density lipoprotein receptor-related protein 1.	Thrombospondin-1.	0.797
LRP1B	LRP4	ENSTSYP00000000479	ENSTSYP00000009906	Low-density lipoprotein receptor-related protein 1B.	Low-density lipoprotein receptor-related protein 4.	0.816
LRP1B	THBS1	ENSTSYP00000000479	ENSTSYP00000002362	Low-density lipoprotein receptor-related protein 1B.	Thrombospondin-1.	0.580
LRP4	LRP1	ENSTSYP00000009906	ENSTSYP00000017567	Low-density lipoprotein receptor-related protein 4.	Prolow-density lipoprotein receptor-related protein 1.	0.816
LRP4	LRP1B	ENSTSYP00000009906	ENSTSYP00000000479	Low-density lipoprotein receptor-related protein 4.	Low-density lipoprotein receptor-related protein 1B.	0.816