(95 nodes) Protein-tyrosine phosphatase-like network (Carlito syrichta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MTM1	Myotubularin isoform X1. (603 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (336 aa)
	DUSP23	Dual specificity protein phosphatase 23. (135 aa)
	SSH2	Protein phosphatase Slingshot homolog 2. (1448 aa)
	MTMR1	Myotubularin-related protein 1. (673 aa)
	CDKN3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)
	DNAJC6	Putative tyrosine-protein phosphatase auxilin isoform X1. (935 aa)
	DUSP27	Inactive dual specificity phosphatase 27; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (1148 aa)
	PTPN22	Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (811 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (169 aa)
	LOC103268987	Receptor-type tyrosine-protein phosphatase T isoform X3. (738 aa)
	MTMR3	Myotubularin-related protein 3 isoform X1. (1199 aa)
	PTPRO	Receptor-type tyrosine-protein phosphatase O isoform X1. (1223 aa)
	PALD1	Paladin. (856 aa)
	PTP4A3	Protein tyrosine phosphatase type IVA 3. (169 aa)
	PTPRF	Receptor-type tyrosine-protein phosphatase F. (1908 aa)
	PTPRZ1	Receptor-type tyrosine-protein phosphatase zeta isoform X1. (2301 aa)
	DUSP4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa)
	DUSP26	Dual specificity protein phosphatase 26; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
	TNS1	Tensin-1. (1728 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (908 aa)
	PTPN7	Tyrosine-protein phosphatase non-receptor type 7 isoform X1. (443 aa)
	PTPRB	Receptor-type tyrosine-protein phosphatase beta isoform X1. (2216 aa)
	MTMR14	Myotubularin-related protein 14 isoform X1. (649 aa)
	PTPRU	Receptor-type tyrosine-protein phosphatase U. (1446 aa)
	MTMR4	Myotubularin-related protein 4. (1195 aa)
	MTMR7	Myotubularin-related protein 7. (371 aa)
	LOC103263202	Myotubularin-related protein 7-like. (98 aa)
	PTP4A2	Protein tyrosine phosphatase type IVA 2 isoform X1. (167 aa)
	SBF1	Myotubularin-related protein 5. (1874 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (332 aa)
	CDC14B	Dual specificity protein phosphatase CDC14B. (498 aa)
	DUSP19	Dual specificity protein phosphatase 19 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (221 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type 6. (402 aa)
	SSH1	Protein phosphatase Slingshot homolog 1. (1044 aa)
	PTPRQ	Phosphatidylinositol phosphatase PTPRQ. (2333 aa)
	LOC103261409	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like. (168 aa)
	PTPN23	Tyrosine-protein phosphatase non-receptor type 23 isoform X1. (1636 aa)
	DUSP10	Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (486 aa)
	PTPRG	LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase gamma-like. (1351 aa)
	LOC103269571	Tyrosine-protein phosphatase non-receptor type 9. (524 aa)
	TNS2	LOW QUALITY PROTEIN: tensin-2. (1351 aa)
	DUSP13	Dual specificity protein phosphatase 13 isoform X3; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (333 aa)
	PTPDC1	Protein tyrosine phosphatase domain-containing protein 1 isoform X1. (804 aa)
	DUSP5	Dual specificity protein phosphatase 5. (318 aa)
	TNS3	Tensin-3. (1445 aa)
	DUSP22	Dual specificity protein phosphatase 22. (102 aa)
	MTMR12	Myotubularin-related protein 12. (748 aa)
	PTPN20	Tyrosine-protein phosphatase non-receptor type 20. (225 aa)
	PTPN4	Tyrosine-protein phosphatase non-receptor type 4. (898 aa)
	PTPRH	Receptor-type tyrosine-protein phosphatase H. (997 aa)
	DUSP15	Dual specificity protein phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (203 aa)
	PTPRN	Receptor-type tyrosine-protein phosphatase-like N isoform X1. (978 aa)
	PTPRR	Receptor-type tyrosine-protein phosphatase R. (355 aa)
	DUSP9	Dual specificity protein phosphatase 9; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (314 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	GAK	cyclin-G-associated kinase isoform X1. (1310 aa)
	DUSP2	Dual specificity protein phosphatase 2; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (314 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (415 aa)
	SSH3	Protein phosphatase Slingshot homolog 3. (653 aa)
	LOC103256486	Receptor-type tyrosine-protein phosphatase mu isoform X1. (345 aa)
	PTP4A1	Protein tyrosine phosphatase type IVA 1. (173 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (800 aa)
	LOC103253085	LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 9-like. (591 aa)
	MTMR11	Myotubularin-related protein 11. (695 aa)
	DUSP16	Dual specificity protein phosphatase 16. (663 aa)
	MTMR2	Myotubularin-related protein 2. (629 aa)
	PTPRE	Receptor-type tyrosine-protein phosphatase. (703 aa)
	MTMR8	Myotubularin-related protein 8. (450 aa)
	MTMR10	Myotubularin-related protein 10 isoform X1. (773 aa)
	PTPN18	Tyrosine-protein phosphatase non-receptor type 18. (454 aa)
	RNGTT	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
	EPM2A	Laforin. (285 aa)
	DUSP28	Dual specificity phosphatase 28. (179 aa)
	PTPN5	Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (565 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (663 aa)
	MTMR6	Myotubularin-related protein 6. (621 aa)
	DUSP12	Dual specificity protein phosphatase 12 isoform X2. (340 aa)
	STYX	Serine/threonine/tyrosine-interacting protein. (223 aa)
	PTPN13	Tyrosine-protein phosphatase non-receptor type 13 isoform X1. (2492 aa)
	DUPD1	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (220 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta. (1260 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1186 aa)
	DUSP11	RNA/RNP complex-1-interacting phosphatase. (379 aa)
	DUSP14	Dual specificity protein phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (175 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C. (601 aa)
	MTMR9	Myotubularin-related protein 9. (444 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (434 aa)
	PTPRD	Receptor-type tyrosine-protein phosphatase delta isoform X2. (1912 aa)
	SBF2	Myotubularin-related protein 13 isoform X2. (1804 aa)
	CDC14A	Dual specificity protein phosphatase CDC14A isoform X1. (575 aa)
	PTPRK	Receptor-type tyrosine-protein phosphatase kappa isoform X3. (1084 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC14A	CDC14B	ENSTSYP00000001512	ENSTSYP00000028102	Dual specificity protein phosphatase CDC14A isoform X1.	Dual specificity protein phosphatase CDC14B.	0.831
CDC14A	EPM2A	ENSTSYP00000001512	ENSTSYP00000006286	Dual specificity protein phosphatase CDC14A isoform X1.	Laforin.	0.403
CDC14A	GAK	ENSTSYP00000001512	ENSTSYP00000031614	Dual specificity protein phosphatase CDC14A isoform X1.	cyclin-G-associated kinase isoform X1.	0.552
CDC14B	CDC14A	ENSTSYP00000028102	ENSTSYP00000001512	Dual specificity protein phosphatase CDC14B.	Dual specificity protein phosphatase CDC14A isoform X1.	0.831
CDC14B	GAK	ENSTSYP00000028102	ENSTSYP00000031614	Dual specificity protein phosphatase CDC14B.	cyclin-G-associated kinase isoform X1.	0.552
CDKN3	DUPD1	ENSTSYP00000023500	ENSTSYP00000003500	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.482
CDKN3	DUSP13	ENSTSYP00000023500	ENSTSYP00000011872	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	Dual specificity protein phosphatase 13 isoform X3; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.443
CDKN3	DUSP26	ENSTSYP00000023500	ENSTSYP00000017807	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	Dual specificity protein phosphatase 26; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.426
CDKN3	DUSP3	ENSTSYP00000023500	ENSTSYP00000021803	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.458
CDKN3	GAK	ENSTSYP00000023500	ENSTSYP00000031614	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	cyclin-G-associated kinase isoform X1.	0.552
DNAJC6	GAK	ENSTSYP00000022887	ENSTSYP00000031614	Putative tyrosine-protein phosphatase auxilin isoform X1.	cyclin-G-associated kinase isoform X1.	0.994
DNAJC6	TNS1	ENSTSYP00000022887	ENSTSYP00000017736	Putative tyrosine-protein phosphatase auxilin isoform X1.	Tensin-1.	0.436
DNAJC6	TNS2	ENSTSYP00000022887	ENSTSYP00000024801	Putative tyrosine-protein phosphatase auxilin isoform X1.	LOW QUALITY PROTEIN: tensin-2.	0.436
DNAJC6	TNS3	ENSTSYP00000022887	ENSTSYP00000011100	Putative tyrosine-protein phosphatase auxilin isoform X1.	Tensin-3.	0.436
DUPD1	CDKN3	ENSTSYP00000003500	ENSTSYP00000023500	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	0.482
DUPD1	GAK	ENSTSYP00000003500	ENSTSYP00000031614	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	cyclin-G-associated kinase isoform X1.	0.567
DUPD1	PTPN20	ENSTSYP00000003500	ENSTSYP00000008667	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 20.	0.465
DUPD1	PTPN5	ENSTSYP00000003500	ENSTSYP00000004396	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 5 isoform X1.	0.727
DUPD1	PTPN7	ENSTSYP00000003500	ENSTSYP00000017435	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type 7 isoform X1.	0.630
DUPD1	PTPRQ	ENSTSYP00000003500	ENSTSYP00000014352	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Phosphatidylinositol phosphatase PTPRQ.	0.511