STRINGSTRING
SHC1 SHC1 HBEGF HBEGF HSP90AA1 HSP90AA1 FYN FYN ERBB2 ERBB2 RPS27A RPS27A LOC103258503 LOC103258503 ENSTSYP00000031842 ENSTSYP00000031842 BTC BTC YES1 YES1 SOS1 SOS1 HRAS HRAS CSDE1 CSDE1 PRKCA PRKCA PLCG1 PLCG1 PIK3CA PIK3CA KRAS KRAS PTPN12 PTPN12 NRG4 NRG4 EREG EREG FNDC3A FNDC3A EGFR EGFR NRG3 NRG3 GAB1 GAB1 FNDC3B FNDC3B ERBB4 ERBB4 PRKCD PRKCD PTPN18 PTPN18 NRG2 NRG2 ENSTSYP00000014559 ENSTSYP00000014559 AKT2 AKT2 EGF EGF PTK6 PTK6 GRB7 GRB7 LOC103272376 LOC103272376 ENSTSYP00000017997 ENSTSYP00000017997 PIK3R1 PIK3R1 CDC37 CDC37 ENSTSYP00000022222 ENSTSYP00000022222 ENSTSYP00000022518 ENSTSYP00000022518 RNF41 RNF41 UBA52 UBA52 LOC103275563 LOC103275563 NRAS NRAS ERBIN ERBIN CUL5 CUL5 DIAPH1 DIAPH1 USP8 USP8 AKT3 AKT3 SRC SRC GRB2 GRB2 GRAP GRAP ENSTSYP00000027147 ENSTSYP00000027147 ENSTSYP00000027808 ENSTSYP00000027808 NRG1 NRG1 ENSTSYP00000030676 ENSTSYP00000030676 AKT1 AKT1 STUB1 STUB1 LOC110596262 LOC110596262
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHC1SHC-transforming protein 1 isoform X1. (474 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (813 aa)
FYNTyrosine-protein kinase. (537 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC103258503Protein MEMO1. (293 aa)
ENSTSYP00000031842annotation not available (607 aa)
BTCProbetacellulin. (178 aa)
YES1Tyrosine-protein kinase. (546 aa)
SOS1Son of sevenless homolog 1 isoform X2. (441 aa)
HRASGTPase HRas isoform X6. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (842 aa)
PRKCAProtein kinase C. (614 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KRASGTPase KRas isoform X1. (189 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (663 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
EREGProepiregulin. (167 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1196 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform isoform X2. (344 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (700 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1203 aa)
ERBB4Receptor protein-tyrosine kinase. (1280 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
PTPN18Tyrosine-protein phosphatase non-receptor type 18. (454 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform. (243 aa)
ENSTSYP00000014559annotation not available (115 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
PTK6Tyrosine-protein kinase. (450 aa)
GRB7Growth factor receptor-bound protein 7 isoform X1. (531 aa)
LOC103272376LOW QUALITY PROTEIN: protein MEMO1-like. (280 aa)
ENSTSYP00000017997annotation not available (123 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
CDC37Hsp90 co-chaperone Cdc37 isoform X2. (378 aa)
ENSTSYP00000022222annotation not available (155 aa)
ENSTSYP00000022518annotation not available (698 aa)
RNF41E3 ubiquitin-protein ligase NRDP1 isoform X1. (317 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
LOC103275563Receptor tyrosine-protein kinase erbB-3. (169 aa)
NRASGTPase NRas. (189 aa)
ERBINErbin. (1420 aa)
CUL5Cullin-5; Belongs to the cullin family. (810 aa)
DIAPH1Protein diaphanous homolog 1. (1236 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1117 aa)
AKT3RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa)
SRCTyrosine-protein kinase. (542 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
GRAPGRB2-related adapter protein. (188 aa)
ENSTSYP00000027147annotation not available (149 aa)
ENSTSYP00000027808annotation not available (611 aa)
NRG1Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
ENSTSYP00000030676annotation not available (108 aa)
AKT1Non-specific serine/threonine protein kinase. (393 aa)
STUB1E3 ubiquitin-protein ligase CHIP isoform X1. (299 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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