38 items (Carlito syrichta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	STAT5A	Signal transducer and activator of transcription. (669 aa)
	NCSTN	Nicastrin isoform X1. (708 aa)
	PGR	Progesterone receptor. (338 aa)
	STMN1	Stathmin; Belongs to the stathmin family. (78 aa)
	ADAM17	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (824 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
	LOC103257773	Stathmin; Belongs to the stathmin family. (185 aa)
	YAP1	Transcriptional coactivator YAP1 isoform X1. (326 aa)
	MXD4	MAX dimerization protein 4. (211 aa)
	PSENEN	Gamma-secretase subunit PEN-2. (101 aa)
	WWOX	WW domain-containing oxidoreductase. (186 aa)
	ENSTSYP00000011538	annotation not available (138 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (209 aa)
	APH1B	Gamma-secretase subunit APH-1B. (245 aa)
	ADAP2	arf-GAP with dual PH domain-containing protein 2. (349 aa)
	TAB2	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1280 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1203 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
	NCOR1	Nuclear receptor corepressor 1 isoform X8. (2437 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1196 aa)
	EREG	Proepiregulin. (167 aa)
	NRG4	Pro-neuregulin-4, membrane-bound isoform. (116 aa)
	CSN2	Casein beta. (216 aa)
	LOC103249515	WW domain-containing oxidoreductase-like. (185 aa)
	BTC	Probetacellulin. (178 aa)
	NRG2	Pro-neuregulin-2, membrane-bound isoform. (243 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	ADAP1	arf-GAP with dual PH domain-containing protein 1. (232 aa)
	APH1A	Gamma-secretase subunit APH-1A isoform X1. (265 aa)
	LOC103269764	Stromal cell-derived factor 1-like; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	SPARC	SPARC isoform X3. (303 aa)
	GFAP	Glial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (474 aa)
	NRG1	Pro-neuregulin-1, membrane-bound isoform isoform X3. (645 aa)
	MXD1	Max dimerization protein 1 isoform X1. (221 aa)
	ENSTSYP00000025836	annotation not available (138 aa)
	S100B	Protein S100; Belongs to the S-100 family. (92 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	BTC	ENSTSYP00000008166	ENSTSYP00000001351	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Probetacellulin.	0.407
ADAM17	EREG	ENSTSYP00000008166	ENSTSYP00000004778	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Proepiregulin.	0.400
ADAM17	HBEGF	ENSTSYP00000008166	ENSTSYP00000010637	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Proheparin-binding EGF-like growth factor.	0.870
ADAM17	NCSTN	ENSTSYP00000008166	ENSTSYP00000023582	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Nicastrin isoform X1.	0.649
ADAM17	PSEN1	ENSTSYP00000008166	ENSTSYP00000032237	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.486
ADAM17	PSEN2	ENSTSYP00000008166	ENSTSYP00000018767	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.562
ADAM17	PSENEN	ENSTSYP00000008166	ENSTSYP00000014007	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Gamma-secretase subunit PEN-2.	0.561
APH1A	APH1B	ENSTSYP00000030221	ENSTSYP00000008833	Gamma-secretase subunit APH-1A isoform X1.	Gamma-secretase subunit APH-1B.	0.891
APH1A	ERBB4	ENSTSYP00000030221	ENSTSYP00000006840	Gamma-secretase subunit APH-1A isoform X1.	Receptor protein-tyrosine kinase.	0.502
APH1A	NCSTN	ENSTSYP00000030221	ENSTSYP00000023582	Gamma-secretase subunit APH-1A isoform X1.	Nicastrin isoform X1.	0.999
APH1A	PSEN1	ENSTSYP00000030221	ENSTSYP00000032237	Gamma-secretase subunit APH-1A isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.999
APH1A	PSEN2	ENSTSYP00000030221	ENSTSYP00000018767	Gamma-secretase subunit APH-1A isoform X1.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.999
APH1A	PSENEN	ENSTSYP00000030221	ENSTSYP00000014007	Gamma-secretase subunit APH-1A isoform X1.	Gamma-secretase subunit PEN-2.	0.999
APH1B	APH1A	ENSTSYP00000008833	ENSTSYP00000030221	Gamma-secretase subunit APH-1B.	Gamma-secretase subunit APH-1A isoform X1.	0.891
APH1B	ERBB4	ENSTSYP00000008833	ENSTSYP00000006840	Gamma-secretase subunit APH-1B.	Receptor protein-tyrosine kinase.	0.481
APH1B	NCSTN	ENSTSYP00000008833	ENSTSYP00000023582	Gamma-secretase subunit APH-1B.	Nicastrin isoform X1.	0.998
APH1B	PSEN1	ENSTSYP00000008833	ENSTSYP00000032237	Gamma-secretase subunit APH-1B.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.998
APH1B	PSEN2	ENSTSYP00000008833	ENSTSYP00000018767	Gamma-secretase subunit APH-1B.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.998
APH1B	PSENEN	ENSTSYP00000008833	ENSTSYP00000014007	Gamma-secretase subunit APH-1B.	Gamma-secretase subunit PEN-2.	0.998
BTC	ADAM17	ENSTSYP00000001351	ENSTSYP00000008166	Probetacellulin.	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	0.407