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UPB1 UPB1 SETBP1 SETBP1 PNP PNP NT5C1A NT5C1A CEP44 CEP44 ENSTSYP00000001290 ENSTSYP00000001290 TXNDC2 TXNDC2 AK5 AK5 ENTPD1 ENTPD1 ENTPD7 ENTPD7 TXNDC8 TXNDC8 ENSTSYP00000002367 ENSTSYP00000002367 LOC103268588 LOC103268588 UPP1 UPP1 DPYS DPYS ADPRM ADPRM NT5C3A NT5C3A NME9 NME9 ENTPD3 ENTPD3 AK8 AK8 ADSS ADSS NME8 NME8 CDADC1 CDADC1 ENTPD5 ENTPD5 RRM2B RRM2B NME1 NME1 CTPS1 CTPS1 AK9 AK9 NUDT15 NUDT15 ADK ADK LOC103255941 LOC103255941 CMPK2 CMPK2 UCK2 UCK2 PFAS PFAS LOC103271570 LOC103271570 GART GART PPAT PPAT ATIC ATIC AGXT2 AGXT2 IQCJ IQCJ TK1 TK1 SCHIP1 SCHIP1 GMPS GMPS PRTFDC1 PRTFDC1 GMPR GMPR AK4 AK4 ENKUR ENKUR PAICS PAICS RRM2 RRM2 DCK DCK TXNRD1 TXNRD1 NUDT13 NUDT13 NUDT5 NUDT5 XDH XDH RRM1 RRM1 DGUOK DGUOK UMPS UMPS ENTPD4 ENTPD4 DUT DUT NT5DC1 NT5DC1 ADA ADA TK2 TK2 IMPDH2 IMPDH2 QRICH1 QRICH1 CTPS2 CTPS2 AMPD1 AMPD1 ENSTSYP00000014426 ENSTSYP00000014426 ENSTSYP00000015529 ENSTSYP00000015529 NT5M NT5M ADSL ADSL NT5C2 NT5C2 DNPH1 DNPH1 IMPDH1 IMPDH1 NUDT6 NUDT6 ENSTSYP00000017358 ENSTSYP00000017358 ENSTSYP00000017818 ENSTSYP00000017818 DTYMK DTYMK DPYD DPYD GSR GSR GUK1 GUK1 ITPA ITPA GLRX2 GLRX2 LOC103269705 LOC103269705 APRT APRT SAMHD1 SAMHD1 ENSTSYP00000021094 ENSTSYP00000021094 UCK1 UCK1 LOC103266009 LOC103266009 AMPD3 AMPD3 AK1 AK1 PUDP PUDP CAD CAD IPO13 IPO13 AMPD2 AMPD2 LOC103255677 LOC103255677 DCTD DCTD DHODH DHODH NUDT18 NUDT18 ADSSL1 ADSSL1 AK6 AK6 TYMS TYMS ENSTSYP00000027041 ENSTSYP00000027041 ENSTSYP00000027580 ENSTSYP00000027580 ENSTSYP00000027795 ENSTSYP00000027795 NT5E NT5E ENSTSYP00000028205 ENSTSYP00000028205 ENSTSYP00000028378 ENSTSYP00000028378 DALRD3 DALRD3 LOC103257595 LOC103257595 NME4 NME4 NRSN1 NRSN1 GDA GDA TXNRD3 TXNRD3 GMPR2 GMPR2 ENTPD8 ENTPD8 CMPK1 CMPK1 LOC103250167 LOC103250167 ENSTSYP00000030901 ENSTSYP00000030901 NUDT16L1 NUDT16L1 NT5C NT5C PAPOLG PAPOLG NUDT1 NUDT1 AK2 AK2 HPRT1 HPRT1 UCKL1 UCKL1 ENSTSYP00000032485 ENSTSYP00000032485 GLRX GLRX ENTPD2 ENTPD2 CDA CDA ADAL ADAL ENTPD6 ENTPD6 LOC103262532 LOC103262532
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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UPB1Beta-ureidopropionase. (384 aa)
SETBP1SET-binding protein. (1568 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
NT5C1ACytosolic 5'-nucleotidase 1A. (368 aa)
CEP44Centrosomal protein of 44 kDa isoform X2. (389 aa)
ENSTSYP00000001290annotation not available (293 aa)
TXNDC2Thioredoxin domain-containing protein 2. (506 aa)
AK5Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (297 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (524 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (605 aa)
TXNDC8Thioredoxin; Belongs to the thioredoxin family. (129 aa)
ENSTSYP00000002367annotation not available (95 aa)
LOC103268588Thioredoxin. (105 aa)
UPP1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
DPYSDihydropyrimidinase. (426 aa)
ADPRMManganese-dependent ADP-ribose/CDP-alcohol diphosphatase. (342 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
NME9LOW QUALITY PROTEIN: thioredoxin domain-containing protein 6; Belongs to the NDK family. (313 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa)
AK8Adenylate kinase 8-like; Belongs to the adenylate kinase family. (345 aa)
ADSSAdenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
NME8Thioredoxin domain-containing protein 3. (585 aa)
CDADC1Cytidine and dCMP deaminase domain-containing protein 1 isoform X3. (514 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 isoform X1; Belongs to the GDA1/CD39 NTPase family. (428 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B. (335 aa)
NME1Nucleoside diphosphate kinase. (146 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (591 aa)
AK9LOW QUALITY PROTEIN: adenylate kinase 9. (421 aa)
NUDT15Nucleotide triphosphate diphosphatase NUDT15. (169 aa)
ADKAdenosine kinase. (271 aa)
LOC103255941Cytosolic 5'-nucleotidase 1B-like isoform X3. (608 aa)
CMPK2UMP-CMP kinase 2, mitochondrial. (208 aa)
UCK2Uridine-cytidine kinase 2. (224 aa)
PFASPhosphoribosylformylglycinamidine synthase. (1343 aa)
LOC103271570Adenylate kinase 9-like. (732 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3. (433 aa)
PPATAmidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (517 aa)
ATICBifunctional purine biosynthesis protein PURH. (591 aa)
AGXT2Alanine--glyoxylate aminotransferase 2, mitochondrial isoform X1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (514 aa)
IQCJIQ domain-containing protein J. (111 aa)
TK1Thymidine kinase. (267 aa)
SCHIP1Schwannomin-interacting protein 1 isoform X1. (468 aa)
GMPSGMP synthase [glutamine-hydrolyzing]. (705 aa)
PRTFDC1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (208 aa)
GMPRGMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa)
AK4Adenylate kinase 4, mitochondrial; Belongs to the adenylate kinase family. (171 aa)
ENKUREnkurin. (256 aa)
PAICSMultifunctional protein ADE2. (528 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2. (411 aa)
DCKDeoxycytidine kinase. (169 aa)
TXNRD1Thioredoxin reductase 1, cytoplasmic. (567 aa)
NUDT13Nucleoside diphosphate-linked moiety X motif 13 isoform X1. (351 aa)
NUDT5ADP-sugar pyrophosphatase isoform X1; Belongs to the Nudix hydrolase family. (219 aa)
XDHXanthine dehydrogenase/oxidase. (1333 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
DGUOKDeoxyguanosine kinase, mitochondrial isoform X1. (277 aa)
UMPSUridine 5'-monophosphate synthase. (480 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family. (624 aa)
DUTDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1. (242 aa)
NT5DC15'-nucleotidase domain-containing protein 1. (455 aa)
ADAAdenosine deaminase. (363 aa)
TK2Thymidine kinase 2, mitochondrial isoform X5. (278 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
QRICH1Glutamine-rich protein 1. (772 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (483 aa)
AMPD1LOW QUALITY PROTEIN: AMP deaminase 1. (428 aa)
ENSTSYP00000014426annotation not available (130 aa)
ENSTSYP00000015529annotation not available (366 aa)
NT5M5'(3')-deoxyribonucleotidase, mitochondrial. (234 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (502 aa)
NT5C2Cytosolic purine 5'-nucleotidase isoform X1. (566 aa)
DNPH12'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (207 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (585 aa)
NUDT6Nucleoside diphosphate-linked moiety X motif 6 isoform X4; Belongs to the Nudix hydrolase family. (147 aa)
ENSTSYP00000017358annotation not available (54 aa)
ENSTSYP00000017818annotation not available (157 aa)
DTYMKThymidylate kinase isoform X2. (80 aa)
DPYDLOW QUALITY PROTEIN: dihydropyrimidine dehydrogenase [NADP(+)]. (833 aa)
GSRGlutathione reductase, mitochondrial. (490 aa)
GUK1Guanylate kinase. (242 aa)
ITPAInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (209 aa)
GLRX2Glutaredoxin 2. (123 aa)
LOC103269705LOW QUALITY PROTEIN: 5'-nucleotidase domain-containing protein 1-like. (447 aa)
APRTAdenine phosphoribosyltransferase. (164 aa)
SAMHD1Deoxynucleoside triphosphate triphosphohydrolase SAMHD1. (583 aa)
ENSTSYP00000021094annotation not available (462 aa)
UCK1Uridine-cytidine kinase 1 isoform X1. (282 aa)
LOC103266009Thioredoxin; Belongs to the thioredoxin family. (106 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (777 aa)
AK1Adenylate kinase isoenzyme 1; Belongs to the adenylate kinase family. (179 aa)
PUDPPseudouridine-5'-phosphatase. (233 aa)
CADCAD protein. (2211 aa)
IPO13Importin-13. (963 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (858 aa)
LOC103255677Adenylate kinase isoenzyme 5-like; Belongs to the adenylate kinase family. (77 aa)
DCTDDeoxycytidylate deaminase. (96 aa)
DHODHDihydroorotate dehydrogenase (Quinone), mitochondrial. (227 aa)
NUDT18LOW QUALITY PROTEIN: 8-oxo-dGDP phosphatase NUDT18; Belongs to the Nudix hydrolase family. (295 aa)
ADSSL1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
TYMSThymidylate synthase isoform X1. (313 aa)
ENSTSYP00000027041annotation not available (485 aa)
ENSTSYP00000027580annotation not available (90 aa)
ENSTSYP00000027795annotation not available (290 aa)
NT5ELOW QUALITY PROTEIN: 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (462 aa)
ENSTSYP00000028205annotation not available (105 aa)
ENSTSYP00000028378annotation not available (117 aa)
DALRD3DALR anticodon-binding domain-containing protein 3 isoform X1. (543 aa)
LOC103257595Thioredoxin; Belongs to the thioredoxin family. (98 aa)
NME4Nucleoside diphosphate kinase. (171 aa)
NRSN1Neurensin-1. (195 aa)
GDAGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (464 aa)
TXNRD3Thioredoxin reductase 3 isoform X1. (644 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (396 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (439 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (228 aa)
LOC103250167Adenylate kinase 7. (366 aa)
ENSTSYP00000030901annotation not available (403 aa)
NUDT16L1Tudor-interacting repair regulator protein isoform X1. (231 aa)
NT5C5'(3')-deoxyribonucleotidase, cytosolic type. (113 aa)
PAPOLGpoly(A) polymerase gamma. (745 aa)
NUDT17,8-dihydro-8-oxoguanine triphosphatase; Belongs to the Nudix hydrolase family. (171 aa)
AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (232 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (219 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (520 aa)
ENSTSYP00000032485annotation not available (93 aa)
GLRXGlutaredoxin-1 isoform X1. (106 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (383 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (145 aa)
ADALAdenosine deaminase-like protein. (357 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6 isoform X1; Belongs to the GDA1/CD39 NTPase family. (477 aa)
LOC103262532Dihydroorotate dehydrogenase (Quinone), mitochondrial. (196 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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