STRINGSTRING
ATF2 ATF2 IKBKB IKBKB TLR4 TLR4 FGB FGB NLRP9 NLRP9 NFKBIA NFKBIA CHUK CHUK PPP4R4 PPP4R4 NFKB1 NFKB1 ECSIT ECSIT CREB5 CREB5 MAP2K3 MAP2K3 MAPK10 MAPK10 RIPK2 RIPK2 RELCH RELCH LOC103266633 LOC103266633 CREB1 CREB1 ENSTSYP00000006680 ENSTSYP00000006680 ELK1 ELK1 MYD88 MYD88 TAB2 TAB2 LOC103255197 LOC103255197 BTK BTK S100A8 S100A8 S100A12 S100A12 MAP3K1 MAP3K1 NKIRAS2 NKIRAS2 PPP4R1 PPP4R1 SKP1 SKP1 MAP3K8 MAP3K8 LOC103265120 LOC103265120 RPS6KA3 RPS6KA3 ENSTSYP00000011534 ENSTSYP00000011534 LY96 LY96 CD14 CD14 RPS27A RPS27A NOD1 NOD1 MAPK14 MAPK14 IRAK3 IRAK3 IRAK4 IRAK4 MAPKAPK3 MAPKAPK3 IRAK2 IRAK2 NFKBIB NFKBIB DZIP3 DZIP3 NLRC5 NLRC5 PELI2 PELI2 ENSTSYP00000023689 ENSTSYP00000023689 TP53 TP53 UBA52 UBA52 MAP2K6 MAP2K6 ENSTSYP00000024219 ENSTSYP00000024219 RELA RELA S100B S100B ENSTSYP00000024947 ENSTSYP00000024947 LOC103254497 LOC103254497 LRRC74A LRRC74A NKIRAS1 NKIRAS1 MAPK8 MAPK8 ENSTSYP00000026370 ENSTSYP00000026370 ATF1 ATF1 IKBKG IKBKG MAPK11 MAPK11 VRK3 VRK3 ENSTSYP00000027085 ENSTSYP00000027085 PELI3 PELI3 ENSTSYP00000027147 ENSTSYP00000027147 MAPK3 MAPK3 ENSTSYP00000027938 ENSTSYP00000027938 TAB3 TAB3 DUSP7 DUSP7 LOC103267688 LOC103267688 TONSL TONSL S100A1 S100A1 ENSTSYP00000029633 ENSTSYP00000029633 FOS FOS HMGB1 HMGB1 LRRC34 LRRC34 S100A9 S100A9 ENSTSYP00000030504 ENSTSYP00000030504 CASP8 CASP8 ENSTSYP00000030676 ENSTSYP00000030676 MAP3K7 MAP3K7 IRAK1 IRAK1 MAPK9 MAPK9 DUSP6 DUSP6 MAPKAPK2 MAPKAPK2 RPS6KA1 RPS6KA1 ATF7 ATF7 RPS6KA2 RPS6KA2 TAB1 TAB1 MEF2C MEF2C KHNYN KHNYN LOC103275450 LOC103275450 MAPK1 MAPK1 LRRC71 LRRC71 ENSTSYP00000032288 ENSTSYP00000032288 AGER AGER MAPK7 MAPK7 ENSTSYP00000033058 ENSTSYP00000033058 NLRP1 NLRP1 ENSTSYP00000033242 ENSTSYP00000033242 LOC110596262 LOC110596262 LRRC14 LRRC14 UBE2V1-2 UBE2V1-2 ENSTSYP00000034157 ENSTSYP00000034157 VWC2 VWC2 PELI1 PELI1 MAP3K20 MAP3K20 RPS6KA5 RPS6KA5 FNBP4 FNBP4 PPP2CB PPP2CB NLRP10 NLRP10 LOC103265125 LOC103265125 ALPK1 ALPK1 FGA FGA FGG FGG MAP2K7 MAP2K7 PPP2CA PPP2CA LOC103254100 LOC103254100 MAP2K4 MAP2K4 ENSTSYP00000014559 ENSTSYP00000014559 LOC103254894 LOC103254894 LRRC45 LRRC45 ENSTSYP00000015921 ENSTSYP00000015921 CUL1 CUL1 TRAF6 TRAF6 FBXW11 FBXW11 PPP2R1B PPP2R1B ENSTSYP00000016692 ENSTSYP00000016692 CD36 CD36 USP14 USP14 NOD2 NOD2 PPP2R1A PPP2R1A DUSP4 DUSP4 ENSTSYP00000017997 ENSTSYP00000017997 ENSTSYP00000018213 ENSTSYP00000018213 MAP2K1 MAP2K1 ENSTSYP00000019212 ENSTSYP00000019212 CREM CREM ENSTSYP00000019525 ENSTSYP00000019525 MEF2A MEF2A TNIP2 TNIP2 FOSL2 FOSL2 NLRX1 NLRX1 ENSTSYP00000021013 ENSTSYP00000021013 ENSTSYP00000021542 ENSTSYP00000021542 N4BP1 N4BP1 MAPK15 MAPK15 DUSP3 DUSP3 BTRC BTRC LRRC74B LRRC74B PPP2R5D PPP2R5D ENSTSYP00000022222 ENSTSYP00000022222 APP APP TIRAP TIRAP ENSTSYP00000023484 ENSTSYP00000023484
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (507 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
TLR4Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (840 aa)
FGBFibrinogen beta chain isoform X1. (492 aa)
NLRP9NACHT, LRR and PYD domains-containing protein 9. (992 aa)
NFKBIANF-kappa-B inhibitor alpha. (282 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (744 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X7. (809 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform X1. (431 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2 isoform X1. (539 aa)
RELCHlisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2. (721 aa)
LOC103266633Ubiquitin-conjugating enzyme E2 N-like. (152 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
ENSTSYP00000006680annotation not available (255 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (430 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (321 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
LOC103255197Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
BTKTyrosine-protein kinase. (659 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1346 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X1. (213 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1. (803 aa)
SKP1S-phase kinase-associated protein 1 isoform X2; Belongs to the SKP1 family. (163 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
LOC103265120Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (729 aa)
ENSTSYP00000011534annotation not available (190 aa)
LY96Lymphocyte antigen 96 isoform X1. (160 aa)
CD14Monocyte differentiation antigen CD14. (376 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IRAK3Interleukin-1 receptor-associated kinase 3. (549 aa)
IRAK4Interleukin-1 receptor-associated kinase 4. (460 aa)
MAPKAPK3MAP kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (383 aa)
IRAK2Interleukin-1 receptor-associated kinase-like 2. (626 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (343 aa)
DZIP3E3 ubiquitin-protein ligase DZIP3. (1207 aa)
NLRC5Protein NLRC5. (1843 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog 2. (420 aa)
ENSTSYP00000023689annotation not available (139 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (388 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
MAP2K6LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (352 aa)
ENSTSYP00000024219annotation not available (592 aa)
RELATranscription factor p65. (519 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
ENSTSYP00000024947annotation not available (143 aa)
LOC103254497lisH domain and HEAT repeat-containing protein KIAA1468-like. (391 aa)
LRRC74ALeucine-rich repeat-containing protein 74A. (504 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1. (192 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
ENSTSYP00000026370annotation not available (136 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X1. (269 aa)
IKBKGNF-kappa-B essential modulator. (460 aa)
MAPK11Mitogen-activated protein kinase. (255 aa)
VRK3Inactive serine/threonine-protein kinase VRK3 isoform X1. (473 aa)
ENSTSYP00000027085annotation not available (426 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa)
ENSTSYP00000027147annotation not available (149 aa)
MAPK3Mitogen-activated protein kinase. (363 aa)
ENSTSYP00000027938annotation not available (114 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (711 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
LOC103267688Inactive serine/threonine-protein kinase VRK3-like isoform X2. (419 aa)
TONSLTonsoku-like protein. (1382 aa)
S100A1Protein S100; Belongs to the S-100 family. (140 aa)
ENSTSYP00000029633annotation not available (134 aa)
FOSProto-oncogene c-Fos. (379 aa)
HMGB1High mobility group protein B1. (215 aa)
LRRC34Leucine-rich repeat-containing protein 34. (419 aa)
S100A9Protein S100; Belongs to the S-100 family. (133 aa)
ENSTSYP00000030504annotation not available (156 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (521 aa)
ENSTSYP00000030676annotation not available (108 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
IRAK1Interleukin-1 receptor-associated kinase 1. (618 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (400 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X2. (483 aa)
RPS6KA2Non-specific serine/threonine protein kinase. (729 aa)
TAB1TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X2. (504 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
KHNYNProtein KHNYN. (672 aa)
LOC103275450High mobility group protein B1-like isoform X1. (215 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (363 aa)
LRRC71Leucine-rich repeat-containing protein 71. (419 aa)
ENSTSYP00000032288annotation not available (403 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X2. (403 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (813 aa)
ENSTSYP00000033058annotation not available (142 aa)
NLRP1LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 1. (1435 aa)
ENSTSYP00000033242annotation not available (75 aa)
LOC110596262ubiquitin-40S ribosomal protein S27a-like. (156 aa)
LRRC14Leucine-rich repeat-containing protein 14. (493 aa)
UBE2V1-2Ubiquitin-conjugating enzyme E2 variant 1 isoform X1. (206 aa)
ENSTSYP00000034157annotation not available (419 aa)
VWC2Brorin. (325 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (801 aa)
RPS6KA5Non-specific serine/threonine protein kinase. (594 aa)
FNBP4Formin-binding protein 4 isoform X2. (669 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
NLRP10NACHT, LRR and PYD domains-containing protein 10. (665 aa)
LOC103265125Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa)
ALPK1Alpha-protein kinase 1. (1048 aa)
FGAFibrinogen alpha chain. (872 aa)
FGGFibrinogen gamma chain isoform X1. (461 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7. (414 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC103254100Ubiquitin-conjugating enzyme E2 variant 1-like. (135 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (387 aa)
ENSTSYP00000014559annotation not available (115 aa)
LOC103254894Ubiquitin-conjugating enzyme E2 variant 1-like. (163 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
ENSTSYP00000015921annotation not available (137 aa)
CUL1Cullin-1 isoform X1; Belongs to the cullin family. (776 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (512 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (533 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X3. (667 aa)
ENSTSYP00000016692annotation not available (64 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1040 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (393 aa)
ENSTSYP00000017997annotation not available (123 aa)
ENSTSYP00000018213annotation not available (184 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (381 aa)
ENSTSYP00000019212annotation not available (259 aa)
CREMcAMP-responsive element modulator isoform X7. (111 aa)
ENSTSYP00000019525annotation not available (204 aa)
MEF2AMyocyte-specific enhancer factor 2A isoform X1. (498 aa)
TNIP2TNFAIP3-interacting protein 2. (366 aa)
FOSL2Fos-related antigen 2. (292 aa)
NLRX1NLR family member X1. (974 aa)
ENSTSYP00000021013annotation not available (135 aa)
ENSTSYP00000021542annotation not available (142 aa)
N4BP1NEDD4-binding protein 1. (892 aa)
MAPK15Mitogen-activated protein kinase. (277 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (169 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (589 aa)
LRRC74BLOW QUALITY PROTEIN: leucine-rich repeat-containing protein 74B. (340 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
ENSTSYP00000022222annotation not available (155 aa)
APPAmyloid beta A4 protein isoform X1. (765 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein isoform X1. (228 aa)
ENSTSYP00000023484annotation not available (413 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
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