69 items (Carlito syrichta) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	ENSTSYP00000000627	annotation not available (167 aa)
	LRIG1	Leucine-rich repeats and immunoglobulin-like domains protein 1. (1091 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (209 aa)
	PAG1	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (435 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (474 aa)
	EPS15	Epidermal growth factor receptor substrate 15 isoform X2. (899 aa)
	LPXN	Leupaxin; Belongs to the paxillin family. (391 aa)
	AREG	Amphiregulin isoform X1. (270 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
	ADAM17	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (824 aa)
	LOC103259745	Receptor-type tyrosine-protein phosphatase mu-like. (741 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1203 aa)
	LRIG3	Leucine-rich repeats and immunoglobulin-like domains protein 3. (1096 aa)
	GAB1	GRB2-associated-binding protein 1 isoform X1. (700 aa)
	EGFR	Receptor protein-tyrosine kinase. (1180 aa)
	SH3KBP1	SH3 domain-containing kinase-binding protein 1 isoform X1. (569 aa)
	LRIG2	Leucine-rich repeats and immunoglobulin-like domains protein 2. (1065 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1196 aa)
	EREG	Proepiregulin. (167 aa)
	PXN	LOW QUALITY PROTEIN: paxillin. (1079 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (663 aa)
	KRAS	GTPase KRas isoform X1. (189 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1302 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (842 aa)
	HRAS	GTPase HRas isoform X6. (189 aa)
	SOS1	Son of sevenless homolog 1 isoform X2. (441 aa)
	STAM	Signal transducing adapter molecule 1 isoform X1. (538 aa)
	ADAM10	Disintegrin and metalloproteinase domain-containing protein 10. (679 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
	AAMP	Angio-associated migratory cell protein isoform X2. (451 aa)
	BTC	Probetacellulin. (178 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	ADAM12	Disintegrin and metalloproteinase domain-containing protein 12. (879 aa)
	SH3GL2	endophilin-A1 isoform X2. (350 aa)
	SPRY2	Protein sprouty homolog 2. (338 aa)
	LOC103249307	Receptor-type tyrosine-protein phosphatase kappa-like. (412 aa)
	EPS15L1	Epidermal growth factor receptor substrate 15-like 1 isoform X1. (900 aa)
	LOC110596262	ubiquitin-40S ribosomal protein S27a-like. (156 aa)
	SRC	Tyrosine-protein kinase. (542 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	LOC103256486	Receptor-type tyrosine-protein phosphatase mu isoform X1. (345 aa)
	GRAP	GRB2-related adapter protein. (188 aa)
	CDC42	Cell division control protein 42 homolog. (191 aa)
	ENSTSYP00000031441	annotation not available (131 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
	EPGN	Epigen isoform X1. (153 aa)
	ENSTSYP00000030676	annotation not available (108 aa)
	ENSTSYP00000030193	annotation not available (164 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (898 aa)
	ENSTSYP00000027147	annotation not available (149 aa)
	LOC103251503	LOW QUALITY PROTEIN: epsin-1-like. (321 aa)
	PTPRK	Receptor-type tyrosine-protein phosphatase kappa isoform X3. (1084 aa)
	NRAS	GTPase NRas. (189 aa)
	SH3GL3	endophilin-A3. (289 aa)
	ENSTSYP00000024401	annotation not available (186 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (456 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	ENSTSYP00000022222	annotation not available (155 aa)
	TGFA	Transforming growth factor alpha. (164 aa)
	LOC103268987	Receptor-type tyrosine-protein phosphatase T isoform X3. (738 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
	LOC103267996	Receptor-type tyrosine-protein phosphatase T-like. (338 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7 isoform X1. (705 aa)
	ENSTSYP00000017997	annotation not available (123 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (908 aa)
	ENSTSYP00000014559	annotation not available (115 aa)
	STAM2	Signal transducing adapter molecule 2. (525 aa)

Your Current Organism:

Carlito syrichta

NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	ADAM17	ENSTSYP00000002825	ENSTSYP00000008166	Disintegrin and metalloproteinase domain-containing protein 10.	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	0.888
ADAM10	EGF	ENSTSYP00000002825	ENSTSYP00000008584	Disintegrin and metalloproteinase domain-containing protein 10.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.558
ADAM10	HBEGF	ENSTSYP00000002825	ENSTSYP00000010637	Disintegrin and metalloproteinase domain-containing protein 10.	Proheparin-binding EGF-like growth factor.	0.844
ADAM10	SRC	ENSTSYP00000002825	ENSTSYP00000033233	Disintegrin and metalloproteinase domain-containing protein 10.	Tyrosine-protein kinase.	0.442
ADAM10	TGFA	ENSTSYP00000002825	ENSTSYP00000021904	Disintegrin and metalloproteinase domain-containing protein 10.	Transforming growth factor alpha.	0.524
ADAM12	GRB2	ENSTSYP00000000764	ENSTSYP00000033033	Disintegrin and metalloproteinase domain-containing protein 12.	Growth factor receptor-bound protein 2 isoform X1.	0.558
ADAM12	PIK3R1	ENSTSYP00000000764	ENSTSYP00000020998	Disintegrin and metalloproteinase domain-containing protein 12.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.512
ADAM12	SRC	ENSTSYP00000000764	ENSTSYP00000033233	Disintegrin and metalloproteinase domain-containing protein 12.	Tyrosine-protein kinase.	0.437
ADAM17	ADAM10	ENSTSYP00000008166	ENSTSYP00000002825	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Disintegrin and metalloproteinase domain-containing protein 10.	0.888
ADAM17	AREG	ENSTSYP00000008166	ENSTSYP00000009215	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Amphiregulin isoform X1.	0.478
ADAM17	BTC	ENSTSYP00000008166	ENSTSYP00000001351	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Probetacellulin.	0.407
ADAM17	EGF	ENSTSYP00000008166	ENSTSYP00000008584	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.519
ADAM17	EGFR	ENSTSYP00000008166	ENSTSYP00000005737	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Receptor protein-tyrosine kinase.	0.406
ADAM17	EREG	ENSTSYP00000008166	ENSTSYP00000004778	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Proepiregulin.	0.400
ADAM17	HBEGF	ENSTSYP00000008166	ENSTSYP00000010637	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Proheparin-binding EGF-like growth factor.	0.870
ADAM17	TGFA	ENSTSYP00000008166	ENSTSYP00000021904	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	Transforming growth factor alpha.	0.758
AREG	ADAM17	ENSTSYP00000009215	ENSTSYP00000008166	Amphiregulin isoform X1.	Disintegrin and metalloproteinase domain-containing protein 17 isoform X1.	0.478
AREG	BTC	ENSTSYP00000009215	ENSTSYP00000001351	Amphiregulin isoform X1.	Probetacellulin.	0.816
AREG	CBL	ENSTSYP00000009215	ENSTSYP00000030023	Amphiregulin isoform X1.	E3 ubiquitin-protein ligase CBL.	0.618
AREG	CSDE1	ENSTSYP00000009215	ENSTSYP00000003436	Amphiregulin isoform X1.	Cold shock domain-containing protein E1 isoform X1.	0.481