STRINGSTRING
PIK3R1 PIK3R1 BTC BTC PTPN11 PTPN11 PIK3CA PIK3CA PXN PXN EREG EREG FNDC3A FNDC3A EGFR EGFR GAB1 GAB1 FNDC3B FNDC3B EGF EGF AREG AREG LPXN LPXN PAG1 PAG1 HBEGF HBEGF TGFA TGFA CSK CSK TGFB1I1 TGFB1I1 EPGN EPGN GRAP GRAP GRB2 GRB2 SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (612 aa)
BTCProbetacellulin. (178 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type 11. (532 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PXNLOW QUALITY PROTEIN: paxillin. (1079 aa)
EREGProepiregulin. (167 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1196 aa)
EGFRReceptor protein-tyrosine kinase. (1180 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (700 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1203 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1167 aa)
AREGAmphiregulin isoform X1. (270 aa)
LPXNLeupaxin; Belongs to the paxillin family. (391 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (435 aa)
HBEGFProheparin-binding EGF-like growth factor. (209 aa)
TGFATransforming growth factor alpha. (164 aa)
CSKTyrosine-protein kinase. (450 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (456 aa)
EPGNEpigen isoform X1. (153 aa)
GRAPGRB2-related adapter protein. (188 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
SRCTyrosine-protein kinase. (542 aa)
Your Current Organism:
Carlito syrichta
NCBI taxonomy Id: 1868482
Other names: C. syrichta, Philippine tarsier, Tarsius syrichta
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.