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| | LYN | Tyrosine-protein kinase. (512 aa) |
| | ENSTSYP00000000614 | annotation not available (191 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | RPS27A | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | RB1 | Retinoblastoma-associated protein. (929 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (714 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | DBF4 | Protein DBF4 homolog A. (665 aa) |
| | LIN52 | Protein lin-52 homolog. (106 aa) |
| | MYBL2 | Myb-related protein B. (662 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (430 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa) |
| | PSMA1 | Proteasome subunit alpha type. (264 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | POLE2 | DNA polymerase epsilon subunit 2. (527 aa) |
| | MCM8 | DNA helicase MCM8; Belongs to the MCM family. (832 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (138 aa) |
| | PPP4R4 | Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X7. (809 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (326 aa) |
| | CCNE1 | G1/S-specific cyclin-E1. (410 aa) |
| | PSMA4 | Proteasome subunit alpha type. (179 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit isoform X2. (272 aa) |
| | FNDC3A | Fibronectin type-III domain-containing protein 3A isoform X1. (1196 aa) |
| | CDC7 | Cell division cycle 7-related protein kinase isoform X1. (574 aa) |
| | PSME1 | Proteasome activator complex subunit 1 isoform X1. (250 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | POLA1 | DNA polymerase alpha catalytic subunit. (988 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (455 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19 isoform X2. (209 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | RELCH | lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2. (721 aa) |
| | LIN9 | Protein lin-9 homolog isoform X1. (580 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (417 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform X2. (711 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (435 aa) |
| | FNDC3B | Fibronectin type III domain-containing protein 3B. (1203 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | E2F4 | Transcription factor E2F4. (407 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | PSMC1 | 26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | MCM10 | Protein MCM10 homolog isoform X1. (871 aa) |
| | LOC103272535 | 26S proteasome non-ATPase regulatory subunit 7. (324 aa) |
| | CDK7 | Cyclin-dependent kinase 7 isoform X1. (332 aa) |
| | ENSTSYP00000008181 | annotation not available (412 aa) |
| | TFDP2 | Transcription factor. (448 aa) |
| | TK1 | Thymidine kinase. (267 aa) |
| | PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X3. (453 aa) |
| | E2F2 | Transcription factor E2F2. (423 aa) |
| | PSMC6 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) |
| | RBL1 | Retinoblastoma-like protein 1. (1068 aa) |
| | ORC2 | Origin recognition complex subunit 2 isoform X1. (574 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa) |
| | JAK2 | Tyrosine-protein kinase. (1131 aa) |
| | PPP4R1 | Serine/threonine-protein phosphatase 4 regulatory subunit 1. (803 aa) |
| | ENSTSYP00000009770 | annotation not available (227 aa) |
| | RRM2 | Ribonucleoside-diphosphate reductase subunit M2. (411 aa) |
| | SKP1 | S-phase kinase-associated protein 1 isoform X2; Belongs to the SKP1 family. (163 aa) |
| | RPA2 | Replication protein A 32 kDa subunit. (231 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 isoform X1. (513 aa) |
| | PSMA7 | Proteasome endopeptidase complex. (248 aa) |
| | AKT3 | RAC-gamma serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (419 aa) |
| | GMNN | Geminin isoform X1. (203 aa) |
| | CCNH | cyclin-H; Belongs to the cyclin family. (232 aa) |
| | WEE1 | Wee1-like protein kinase. (432 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 isoform X1. (416 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (422 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | FBXO5 | F-box only protein 5 isoform X1. (447 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 isoform X2. (534 aa) |
| | ORC5 | Origin recognition complex subunit 5. (309 aa) |
| | PSMB3 | Proteasome subunit beta. (207 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (623 aa) |
| | CDK6 | Cyclin-dependent kinase 6. (264 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (420 aa) |
| | PPP2R3A | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1142 aa) |
| | FNBP4 | Formin-binding protein 4 isoform X2. (669 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | E2F5 | Transcription factor E2F5 isoform X1. (300 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | POLE4 | DNA polymerase epsilon subunit 4. (117 aa) |
| | MCM5 | DNA replication licensing factor MCM5; Belongs to the MCM family. (598 aa) |
| | MAX | Protein max isoform X1. (160 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | ENSTSYP00000014559 | annotation not available (115 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | LIN37 | Protein lin-37 homolog isoform X2. (246 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (523 aa) |
| | ENSTSYP00000015529 | annotation not available (366 aa) |
| | ENSTSYP00000015668 | annotation not available (251 aa) |
| | CDK3 | Cyclin-dependent kinase 3 isoform X1; Belongs to the protein kinase superfamily. (305 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (147 aa) |
| | PSMC3 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (450 aa) |
| | CUL1 | Cullin-1 isoform X1; Belongs to the cullin family. (776 aa) |
| | ENSTSYP00000016214 | annotation not available (88 aa) |
| | ENSTSYP00000016249 | annotation not available (98 aa) |
| | RPA4 | Replication protein A 30 kDa subunit. (261 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | PTK6 | Tyrosine-protein kinase. (450 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X3. (667 aa) |
| | CDC45 | Cell division control protein 45 homolog isoform X1. (600 aa) |
| | ENSTSYP00000017776 | annotation not available (292 aa) |
| | MEIOB | LOW QUALITY PROTEIN: meiosis-specific with OB domain-containing protein. (470 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1. (589 aa) |
| | ENSTSYP00000017997 | annotation not available (123 aa) |
| | CDKN2A | Cyclin-dependent kinase inhibitor 2A. (171 aa) |
| | KIAA2012 | LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog; Belongs to the eukaryotic ribosomal protein P1/P2 family. (1143 aa) |
| | CDT1 | DNA replication factor Cdt1. (468 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (484 aa) |
| | CABLES1 | CDK5 and ABL1 enzyme substrate 1. (367 aa) |
| | ENSTSYP00000019039 | annotation not available (232 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | ENSTSYP00000019212 | annotation not available (259 aa) |
| | ENSTSYP00000019245 | annotation not available (285 aa) |
| | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa) |
| | CDK1 | Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa) |
| | TFDP1 | Transcription factor. (399 aa) |
| | PSMB6 | Proteasome subunit beta. (242 aa) |
| | SKP2 | S-phase kinase-associated protein 2. (436 aa) |
| | ENSTSYP00000020949 | annotation not available (151 aa) |
| | ENSTSYP00000021013 | annotation not available (135 aa) |
| | PSME3 | Proteasome activator complex subunit 3 isoform X1. (265 aa) |
| | ENSTSYP00000021540 | annotation not available (291 aa) |
| | E2F3 | Transcription factor E2F3. (334 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | ENSTSYP00000022222 | annotation not available (155 aa) |
| | CCND1 | G1/S-specific cyclin-D1. (156 aa) |
| | LIN54 | Protein lin-54 homolog isoform X1. (749 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa) |
| | ENSTSYP00000023430 | annotation not available (374 aa) |
| | ENSTSYP00000023689 | annotation not available (139 aa) |
| | UBA52 | ubiquitin-60S ribosomal protein L40 isoform X1. (231 aa) |
| | E2F1 | Transcription factor E2F1. (350 aa) |
| | ENSTSYP00000024219 | annotation not available (592 aa) |
| | ENSTSYP00000024485 | annotation not available (234 aa) |
| | ENSTSYP00000024947 | annotation not available (143 aa) |
| | ENSTSYP00000024958 | annotation not available (55 aa) |
| | ENSTSYP00000025346 | annotation not available (194 aa) |
| | LOC103254497 | lisH domain and HEAT repeat-containing protein KIAA1468-like. (391 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X2. (377 aa) |
| | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 isoform X1. (220 aa) |
| | ENSTSYP00000025727 | annotation not available (215 aa) |
| | ENSTSYP00000025787 | annotation not available (389 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 isoform X1. (396 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1. (169 aa) |
| | PRIM2 | DNA primase large subunit. (159 aa) |
| | TYMS | Thymidylate synthase isoform X1. (313 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | ENSTSYP00000026533 | annotation not available (256 aa) |
| | LOC103272490 | DNA primase large subunit. (206 aa) |
| | ENSTSYP00000027087 | annotation not available (52 aa) |
| | CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) |
| | ENSTSYP00000027147 | annotation not available (149 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | ENSTSYP00000027311 | annotation not available (388 aa) |
| | PSMC5 | 26S protease regulatory subunit 8 isoform X2; Belongs to the AAA ATPase family. (398 aa) |
| | ENSTSYP00000028373 | annotation not available (134 aa) |
| | ENSTSYP00000028450 | annotation not available (227 aa) |
| | CDKN1B | LOW QUALITY PROTEIN: cyclin-dependent kinase inhibitor 1B. (197 aa) |
| | ENSTSYP00000028770 | annotation not available (118 aa) |
| | TESMIN | Tesmin. (505 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (231 aa) |
| | LOC103250392 | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (400 aa) |
| | ENSTSYP00000029471 | annotation not available (82 aa) |
| | MCM9 | DNA helicase MCM9; Belongs to the MCM family. (391 aa) |
| | LOC103265662 | DNA polymerase alpha subunit B. (391 aa) |
| | ENSTSYP00000030504 | annotation not available (156 aa) |
| | ENSTSYP00000030676 | annotation not available (108 aa) |
| | MYC | Myc proto-oncogene protein. (376 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | LOC103252110 | G2/mitotic-specific cyclin-B1 isoform X1; Belongs to the cyclin family. (433 aa) |
| | ENSTSYP00000030901 | annotation not available (403 aa) |
| | LOC103262238 | Proteasome subunit alpha type. (261 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (393 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (121 aa) |
| | ENSTSYP00000031721 | annotation not available (275 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | ENSTSYP00000032262 | annotation not available (99 aa) |
| | ENSTSYP00000032333 | annotation not available (309 aa) |
| | CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (166 aa) |
| | ENSTSYP00000032419 | annotation not available (240 aa) |
| | PSME2 | Proteasome activator complex subunit 2 isoform X1. (254 aa) |
| | ENSTSYP00000032718 | annotation not available (175 aa) |
| | E2F6 | Transcription factor E2F6 isoform X2. (281 aa) |
| | PSMC4 | 26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa) |
| | ENSTSYP00000033058 | annotation not available (142 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | LOC110596262 | ubiquitin-40S ribosomal protein S27a-like. (156 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | DYRK1B | Dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X1. (629 aa) |
| | DYRK1A | Dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1. (763 aa) |
| | ENSTSYP00000034042 | annotation not available (110 aa) |
| | ENSTSYP00000034117 | annotation not available (246 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (860 aa) |
| | RBL2 | Retinoblastoma-like protein 2 isoform X1. (1141 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (264 aa) |
| | ENSTSYP00000034921 | annotation not available (296 aa) |
| | ENSTSYP00000035030 | annotation not available (263 aa) |
